Influence of pentoxifylline on cytokine levels and inflammatory parameters in septic shock

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Pathogenetic Mechanisms of Septic Shock

1993 • 1,577 citations

Serum Cytokine Levels in Human Septic Shock

1993 • 882 citations

Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists.

1993 • 837 citations

Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

1992 • 832 citations

Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo.

1985 • 788 citations

Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group.

1989 • 709 citations

Sepsis syndrome

1989 • 523 citations

Shedding of tumor necrosis factor receptors by activated human neutrophils.

1990 • 443 citations

Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog.

1987 • 425 citations

Pentoxifylline suppression of tumor necrosis factor gene transcription.

1991 • 316 citations

Pharmacology of the Endothelium in Ischemia-Reperfusion and Circulatory Shock

1993 • 293 citations

OXPENTIFYLLINE IN ENDOTOXAEMIA

1989 • 263 citations

Tumor necrosis factor in the pathogenesis of infectious diseases

1993 • 239 citations

Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia.

1992 • 238 citations

Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells.

1991 • 235 citations

Prostacyclin protects ischemic reperfused myocardium in the dog by inhibition of neutrophil activation

1987 • 159 citations

Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor.

1990 • 119 citations

Sepsis and its complications: the clinical problem.

1994 • 104 citations

Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality

1990 • 89 citations

Biology of proinflammatory cytokines and their antagonists.

1994 • 87 citations

The Cytokine Network in the Critically Ill

1992 • 86 citations

Prostacyclin and beraprost sodium as suppressors of activated rat polymorphonuclear leukocytes

1990 • 84 citations

The Effects of Aminophylline and Pentoxifylline on Multiple Organ Damage afterEscherichia coliSepsis

1989 • 69 citations

Pretreatment with pentoxifylline improves the hemodynamic and histologic changes and decreases neutrophil adhesiveness in a pig fecal peritonitis model

1990 • 57 citations

Current prospects for the treatment of clinical sepsis.

1994 • 51 citations

Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock

1990 • 49 citations

Interplay of complement and cytokines in the pathogenesis of septic shock

1992 • 46 citations

Fentoxifylline enhances formation of prostacyclin from rat vascular and renal tissue

1983 • 42 citations

Inhibition of ligand binding and antiproliferative effects of tumor necrosis factor and lymphotoxin by soluble forms of recombinant P60 and P80 receptors

1992 • 35 citations

EFFECTS OF RECOMBINANT HUMAN TUMOR NECROSIS FACTOR RECEPTOR (TNFR

1994 • 27 citations

Pentoxifylline at clinically achievable levels inhibits FMLP‐induced neutrophil responses, but not priming, upregulation of cell‐adhesion molecules, or migration induced by GM‐CSF

1993 • 26 citations

The role of prostacyclin in the protective effects of pentoxifylline and other xanthine derivatives in endotoxin action in mice.

1989 • 24 citations

Effects of pentoxifylline in endotoxinemia in human volunteers.

1991 • 21 citations

Cachectin/Tumor Necrosis Factor and Lymphotoxin

1990 • 18 citations

Pentoxifylline treatment of sepsis in conscious Yucatan minipigs.

1992 • 14 citations

Pentoxifylline reduces pulmonary leucostasis and improves capillary patency in a rabbit peritonitis model.

1989 • 10 citations

Effect of Pentoxifylline and HWA 138 on Production of Tumor Necrosis and Interleukin 6 From Monocytes

2015 • 8 citations

Pentoxifylline Pretreatment Decreases Neutrophil Activation During Endotoxic Shock and Improves Survival

2015 • 7 citations

[Therapeutic strategies against mediators of septic shock].

1993 • 4 citations

CARDIORESPIRATORY EFFECTS OF PENTOXIFYLLINE IN SEPTIC AND NON-SEPTIC STATES

1991 • 2 citations

Effect of Pentoxifylline and Analogs on Actin State and Cell Surface Receptor Expression in Human Leukocytes

2015 • 2 citations

Pentoxifylline Causes a Dose Dependent Reduction in Mortality in Patients with Septic Syndrome

1992 • 1 citations

Deleted Work

1955 • 0 citations