OXPENTIFYLLINE IN ENDOTOXAEMIA

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Pentoxifylline

1987 • 1,768 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline

1988 • 564 citations

Pentoxifylline efficacy in the treatment of intermittent claudication: Multicenter controlled double-blind trial with objective assessment of chronic occlusive arterial disease patients

1982 • 425 citations

Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline

1988 • 384 citations

Tumor Necrosis Factor Causes Increased Pulmonary Permeability and Edema: Comparison to Septic Acute Lung Injury

1988 • 338 citations

Receptor Binding and Activation of Polymorphonuclear Neutrophils by Tumor Necrosis Factor-Alpha

1987 • 219 citations

Effect of Pentoxifylline on the Phagocytic Activity, cAMP Levels, and Superoxide Anion Production by Monocytes and Polymorphonuclear Cells

1986 • 214 citations

Lipopolysaccharide-induced gene expression in murine peritoneal macrophages is selectively suppressed by agents that elevate intracellular cAMP.

1989 • 196 citations

Cachectin: A Hormone that Triggers Acute Shock and Chronic Cachexia

1988 • 180 citations

MECHANISMS OF ENDOTOXIN TOLERANCE

1963 • 153 citations

The biology of interleukin 1 and comparison to tumor necrosis factor

1987 • 140 citations

ARDS, Neutrophils, and Pentoxifylline

1988 • 120 citations

Pentoxifylline Decreases Endotoxin-induced Pulmonary Neutrophil Sequestration and Extravascular Protein Accumulation in the Dog

1988 • 117 citations

Attenuation of Acute Lung Injury in Septic Guinea Pigs by Pentoxifylline

1988 • 97 citations

Pentoxifylline inhibits granulocyte and platelet function, including granulocyte priming by platelet activating factor.

1988 • 96 citations

The effect of pentoxifylline in septic shock--new pharmacologic aspects of an established drug.

1989 • 44 citations

Pathophysiology of endotoxin

1985 • 36 citations