A chimeric tyrosine/tryptophan hydroxylase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Current protocols in molecular biology

1988 • 7,584 citations

ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART.

1965 • 1,002 citations

Intricate Regulation of Tyrosine Hydroxylase Activity and Gene Expression

1996 • 673 citations

Complete coding sequence of rat tyrosine hydroxylase mRNA.

1985 • 544 citations

Partial Purification and Characterization of Tryptophan Hydroxylase from Rabbit Hindbrain

1972 • 445 citations

Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation.

1978 • 286 citations

Further studies on tryptophan hydroxylase in rat brainstem and beef pineal

1969 • 225 citations

A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal

1986 • 203 citations

Structure and function of the aromatic amino acid hydroxylases

1995 • 192 citations

Tyrosine hydroxylase: a substrate of cyclic AMP-dependent protein kinase.

1980 • 189 citations

Full-length cDNA for rabbit tryptophan hydroxylase: functional domains and evolution of aromatic amino acid hydroxylases.

1987 • 180 citations

Homology between phenylalanine and tyrosine hydroxylases reveals common structural and functional domains

1985 • 121 citations

Tryptophan hydroxylase. The role of oxygen, iron, and sulfhydryl groups as determinants of stability and catalytic activity.

1980 • 117 citations

Brain tryptophan hydroxylase: purification of, production of antibodies to, and cellular and ultrastructural localization in serotonergic neurons of rat midbrain.

1975 • 109 citations

Demonstration of the Phosphorylation-Dependent Interaction of Tryptophan Hydroxylase with the 14-3-3 Protein

1993 • 103 citations

Regulation of bovine adrenal tyrosine 3-monooxygenase by phosphorylation-dephosphorylation reaction, catalyzed by adenosine 3‘:5‘-monophosphate-dependent protein kinase and phosphoprotein phosphatase.

1979 • 83 citations

Formal Demonstration of the Phosphorylation of Rat Brain Tryptophan Hydroxylase by Ca²⁺/Calmodulin‐Dependent Protein Kinase

1989 • 78 citations

Tryptophan 5‐hydroxylase

1985 • 77 citations

Purification and Properties of Tryptophan 5‐Monooxygenase from Rat Brain‐Stem

1982 • 71 citations

Tryptophan 5‐Monooxygenase from Mouse Mastocytoma P815

1982 • 66 citations

Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylase

1993 • 64 citations

Tyrosine hydroxylase: studies on the phosphorylation of a purified preparation of the brain enzyme by the cyclic AMP-dependent protein kinase.

1981 • 61 citations

Phosphorylation and Activation of Tryptophan Hydroxylase by Exogenous Protein Kinase A

1996 • 56 citations

Tryptophan Hydroxylase Is Phosphorylated by Protein Kinase A

1995 • 54 citations

Use of image analysis to quantitate changes in form of mitochondrial DNA after x-irradiation.

1989 • 52 citations

A Carboxyl Terminal Leucine Zipper Is Required for Tyrosine Hydroxylase Tetramer Formation

1994 • 50 citations

Phosphorylation and Activation of Brain Tryptophan Hydroxylase: Identification of Serine‐58 as a Substrate Site for Protein Kinase A

1997 • 49 citations

A monoclonal antibody to aromatic amino acid hydroxylases. Identification of the epitope

1988 • 48 citations

High-level expression and deletion mutagenesis of human tryptophan hydroxylase.

1994 • 42 citations

Expression and Deletion Mutagenesis of Tryptophan Hydroxylase Fusion Proteins: Delineation of the Enzyme Catalytic Core

1996 • 42 citations

Characterization of the catalytic domain of bovine adrenal tyrosine hydroxylase

1988 • 39 citations

Amino‐Terminal Analysis of Tryptophan Hydroxylase: Protein Kinase Phosphorylation Occurs at Serine‐58

1997 • 39 citations

Radioenzymatic assay for tryptophan hydroxylase: [3H]H2O release assessed by charcoal adsorption

1993 • 39 citations

Identification of the Intersubunit Binding Region in Rat Tyrosine Hydroxylase

1993 • 38 citations

Limited proteolysis of rat brain tyrosine hydroxylase defines an N-terminal region required for regulation of cofactor binding and directing substrate specificity.

1991 • 36 citations

Leucine zippers and coiled-coils in the aromatic amino acid hydroxylases

1991 • 32 citations

Involvement of activator protein in the activation of tryptophan hydroxylase by cAMP‐dependent protein kinase

1990 • 31 citations

Purification and some properties of bovine pineal tryptophan 5-monooxygenase

1974 • 29 citations

Recombinant rabbit tryptophan hydroxylase is a substrate for cAMP-dependent protein kinase

1994 • 29 citations

High-level expression of rat PC12 tyrosine hydroxylase cDNA in Escherichia coli: purification and characterization of the cloned enzyme.

1991 • 27 citations

Catalytic core of rat tyrosine hydroxylase: terminal deletion analysis of bacterially expressed enzyme

1994 • 26 citations

A Sensitive Radiometric Assay for Tryptophan Hydroxylase Applicable to Crude Extracts

1983 • 26 citations

Carboxyl terminal deletion analysis of tryptophan hydroxylase

1997 • 24 citations

Deletion mutagenesis of rat PC12 tyrosine hydroxylase regulatory and catalytic domains

1993 • 24 citations

Stability Properties of Activated Tryptophan Hydroxylase from Rat Midbrain

1982 • 24 citations

Identification of Gln³¹³ and Pro³²⁷ as Residues Critical for Substrate Inhibition in Tyrosine Hydroxylase

1996 • 20 citations

Cloning and Expression of Rabbit and Human Brain Tryptophan-Hydroxylase cDNA in Escherichia Coli

1994 • 18 citations

Deletion mutants of tyrosine hydroxylase identify a region critical for heparin binding

1995 • 17 citations

Partial purification of rabbit hind brain tryptophan hydroxylase by affinity chromatography

1975 • 13 citations

Role of the N‐terminus of rat pheochromocytoma tyrosine hydroxylase in the regulation of the enzyme's activity

1988 • 12 citations

Measurement of Antigen by Enhanced Chemiluminescent Western Blot

1997 • 10 citations

Deletion Mutagenesis of Human Tyrosine Hydroxylase Type 1 Regulatory Domain

1995 • 10 citations

[12] Tryptophan 5-monooxygenase from mouse mastocytoma clone P815

1987 • 8 citations

Lysine241 of Tyrosine Hydroxylase Is Not Required for Binding of Tetrahydrobiopterin Substrate

1993 • 4 citations