The Drosophila Glucose Transporter Gene: cDNA Sequence, Phylogenetic Comparisons, Analysis of Functional Sites and Secondary Structures

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

Combining evolutionary information and neural networks to predict protein secondary structure

1994 • 1,471 citations

Facilitative glucose transporters

1994 • 1,103 citations

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

1993 • 939 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

PHD-an automatic mail server for protein secondary structure prediction

1994 • 561 citations

Structure, Function, and Regulation of the Mammalian Facilitative Glucose Transporter Gene Family

1996 • 369 citations

Mammalian passive glucose transporters: members of an ubiquitous family of active and passive transport proteins

1993 • 279 citations

Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes.

1992 • 170 citations

Complete sequence of the bithorax complex of Drosophila.

1995 • 162 citations

Structure and organization of the human transglutaminase 1 gene.

1992 • 98 citations

Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding.

1994 • 91 citations

Site-directed mutagenesis of GLUT1 in helix 7 residue 282 results in perturbation of exofacial ligand binding.

1992 • 86 citations

Role of Conserved Arginine and Glutamate Residues on the Cytosolic Surface of Glucose Transporters for Transporter Function

1997 • 81 citations

Evidence that functional erythrocyte-type glucose transporters are oligomers.

1991 • 73 citations

Substitution of tyrosine 293 of GLUT1 locks the transporter into an outward facing conformation

1994 • 55 citations

Substitution of leucine for tryptophan 412 does not abolish cytochalasin B labeling but markedly decreases the intrinsic activity of GLUT1 glucose transporter.

1991 • 54 citations

Substitution at Pro385 of GLUT1 perturbs the glucose transport function by reducing conformational flexibility.

1994 • 52 citations

Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process

1998 • 41 citations

Substitution of conserved tyrosine residues in helix 4 (Y143) and 7 (Y293) affects the activity, but not IAPS‐forskolin binding, of the glucose transporter GLUT4

1994 • 27 citations

The Orct gene of Drosophila melanogaster codes for a putative organic cation transporter with six or 12 transmembrane domains

1997 • 27 citations

The glucose transport activity of GLUT1 is markedly decreased by substitution of a single amino acid with a different charge at residue 415

1991 • 25 citations

Structure−Function Studies of the Brain-Type Glucose Transporter, GLUT3: Alanine-Scanning Mutagenesis of Putative Transmembrane Helix VIII and an Investigation of the Role of Proline Residues in Transport Catalysis

1997 • 15 citations

Canine brain glucose transporter 3: Gene sequence, phylogenetic comparisons and analysis of functional sites

1996 • 4 citations

Evolution of the dec-1 eggshell locus in Drosophila

2004 • 4 citations

Evolution of thedec-1 eggshell locus inDrosophila. II. Intraspecific DNA sequence analysis reveals length mutations in a repetitive region inD. melanogaster

1993 • 4 citations