Substitution at Pro385 of GLUT1 perturbs the glucose transport function by reducing conformational flexibility.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution

1985 • 3,049 citations

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

The glucose transporter family: structure, function and tissue-specific expression

1993 • 773 citations

Hypothesis about the function of membrane-buried proline residues in transport proteins.

1986 • 334 citations

Proline kinks in transmembrane α-helices

1991 • 327 citations

Proline residues in transmembrane helixes: structural or dynamic role?

1991 • 240 citations

Structural requirements for binding to the sugar-transport system of the human erythrocyte

1973 • 226 citations

The yeast SNF3 gene encodes a glucose transporter homologous to the mammalian protein.

1988 • 205 citations

Glucose transporter oligomeric structure determines transporter function. Reversible redox-dependent interconversions of tetrameric and dimeric GLUT1.

1992 • 168 citations

Evidence for two asymmetric conformational states in the human erythrocyte sugar-transport system

1975 • 158 citations

Functional Consequences of Proline Mutations in the Cytoplasmic and Transmembrane Sectors of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 157 citations

C-terminal truncated glucose transporter is locked into an inward-facing form without transport activity

1990 • 139 citations

Fourier transform infrared spectroscopic study of the structure and conformational changes of the human erythrocyte glucose transporter.

1987 • 130 citations

ATP regulation of the human red cell sugar transporter.

1986 • 90 citations

Photolabelling of the hexose transporter at external and internal sites: fragmentation patterns and evidence for a conformational change

1987 • 90 citations

Investigation of the structure and function of the human erythrocyte glucose transporter by proteolytic dissection

1987 • 89 citations

Exofacial photolabelling of the human erythrocyte glucose transporter with an azitrifluoroethylbenzoyl-substituted bismannose

1990 • 87 citations

Site-directed mutagenesis of GLUT1 in helix 7 residue 282 results in perturbation of exofacial ligand binding.

1992 • 86 citations

Role of proline residues in the structure and function of a membrane transport protein

1991 • 74 citations

Rapid kinetics of the glucose transporter from human erythrocytes. Detection and measurement of a half-turnover of the purified transporter.

1985 • 57 citations

Molecular mechanisms of transport

1992 • 57 citations

Structural basis of human erythrocyte glucose transporter function in proteoliposome vesicles: circular dichroism measurements.

1987 • 50 citations

Ligand-dependent quenching of tryptophan fluorescence in human erythrocyte hexose transport protein

1990 • 48 citations

Amino acid substitutions and alteration in cation specificity in the melibiose carrier of Escherichia coli.

1988 • 40 citations

Proteolytic dissection as a probe of conformational changes in the human erythrocyte glucose transport protein

1988 • 28 citations

Cytochalasin B interferes with conformational changes of the human erythrocyte glucose transporter induced by internal and external sugar binding

1991 • 21 citations

Comparison of the kinetics and thermodynamics of the carrier systems for glucose and leucine in human red blood cells

1987 • 17 citations

Inhibition of hexose transport in the human erythrocyte by 5, 5′-dithiobis(2-nitrobenzoic acid): Role of an exofacial carrier sulfhydryl group

1989 • 14 citations