Substitution of conserved tyrosine residues in helix 4 (Y143) and 7 (Y293) affects the activity, but not IAPS‐forskolin binding, of the glucose transporter GLUT4

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

Molecular Biology of Mammalian Glucose Transporters

1990 • 852 citations

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

1989 • 601 citations

Family of Glucose-Transporter Genes: Implications for Glucose Homeostasis and Diabetes

1990 • 310 citations

Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes.

1992 • 170 citations

Photolabelling of the hexose transporter at external and internal sites: fragmentation patterns and evidence for a conformational change

1987 • 90 citations

Site-directed mutagenesis of GLUT1 in helix 7 residue 282 results in perturbation of exofacial ligand binding.

1992 • 86 citations

Development of the hormone-sensitive glucose transport activity in differentiating 3T3-L1 murine fibroblasts. Role of the two transporter species and their subcellular localization

1990 • 61 citations

Forskolin inhibits insulin-stimulated glucose transport in rat adipose cells by a direct interaction with the glucose transporter.

1987 • 59 citations

Differentiation of erythrocyte-(GLUT1), liver-(GLUT2), and adipocyte-type (GLUT4) glucose transporters by binding of the inhibitory ligands cytochalasin B, forskolin, dipyridamole, and isobutylmethylxanthine.

1991 • 57 citations

Substitution of tyrosine 293 of GLUT1 locks the transporter into an outward facing conformation

1994 • 55 citations

An improved method of reconstitution of adipocyte glucose transport activity

1982 • 52 citations

Molecular Biology of Sugar Transporters in Plants

1993 • 47 citations

Derivatization of the human erythrocyte glucose transporter using a novel forskolin photoaffinity label.

1987 • 43 citations

Glucose transport activity and photolabelling with 3-[125I]iodo-4-azidophenethylamido-7-0-succinyldeacetyl (IAPS)-forskolin of two mutants at tryptophan-388 and -412 of the glucose transporter GLUT1: dissociation of the binding domains of forskolin and glucose

1993 • 39 citations

Differential sensitivity to guanine nucleotides of basal and insulin‐stimulated glucose transporter activity reconstituted from adipocyte membrane fractions

1989 • 34 citations

Subcellular distribution and activity of glucose transporter isoforms GLUT1 and GLUT4 transiently expressed in COS-7 cells

1992 • 33 citations

The differential role of Cys‐421 and Cys‐429 of the Glut1 glucose transporter in transport inhibition by p‐chloromercuribenzenesulfonic acid (pCMBS) or cytochalasin B (CB)

1992 • 23 citations

Localization of the binding domain of the inhibitory ligand forskolin in the glucose transporter GLUT-4 by photolabeling, proteolytic cleavage and a site-specific antiserum

1992 • 11 citations