Modulation of tumor associated antigen expression and shedding by recombinant human leukocyte and fibroblast interferons

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

1984 • 729 citations

A spectrum of monoclonal antibodies reactive with human mammary tumor cells.

1981 • 565 citations

Augmentation by interferon of human natural and antibody-dependent cell-mediated cytotoxicity

1979 • 532 citations

Human leukocyte interferon produced by E. coli is biologically active

1980 • 528 citations

The structure of eight distinct cloned human leukocyte interferon cDNAs

1981 • 509 citations

The structure of one of the eight or more distinct chromosomal genes for human interferon-α

1980 • 486 citations

Antitumor effects of interferon

1978 • 346 citations

The Biology of the Interferon System

1983 • 327 citations

Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells.

1982 • 305 citations

Isolation and structure of a human fibroblast interferon gene

1980 • 300 citations

Specific molecular activities of recombinant and hybrid leukocyte interferons.

1982 • 298 citations

Imaging of melanoma with L-131-labeled monoclonal antibodies.

1983 • 274 citations

Distribution and molecular characterization of a cell‐surface and a cytoplasmic antigen detectable in human melanoma cells with monoclonal antibodies

1981 • 269 citations

Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy.

1983 • 264 citations

A family of structural genes for human lymphoblastoid (leukocyte-type) interferon

1980 • 253 citations

Regulation of cell proliferation and differentiation by interferons

1985 • 241 citations

Transcriptional induction of two genes in human cells by beta interferon.

1984 • 236 citations

The human interferons—From protein purification and sequence to cloning and expression in bacteria: Before, between, and beyond

1983 • 236 citations

A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferons

1983 • 234 citations

Enhanced expression of surface tumor-associated antigens on human breast and colon tumor cells after recombinant human leukocyte alpha-interferon treatment.

1984 • 217 citations

Enhanced expression of β ₂ -microglobulin and HLA antigens on human lymphoid cells by interferon

1978 • 215 citations

Enhanced expression of HLA antigens and β₂‐microglobulin on interferon‐treated human lymphoid cells

1979 • 152 citations

Effect of human recombinant interferon on cytotoxic activity of natural killer (NK) cells and monocytes

1982 • 152 citations

Imaging with 131I-labeled monoclonal antibodies to a high-molecular-weight melanoma-associated antigen in patients with melanoma: efficacy of whole immunoglobulin and its F(ab')2 fragments.

1985 • 149 citations

Antigenic heterogeneity of surgically removed primary and autologous metastatic human melanoma lesions.

1983 • 144 citations

Modulation by recombinant DNA leukocyte (alpha) and fibroblast (beta) interferons of the expression and shedding of HLA- and tumor-associated antigens by human melanoma cells.

1984 • 142 citations

Human leukocyte interferon: Isolation and characterization of several molecular forms

1981 • 132 citations

Construction and identification of bacterial plasmids containing nucleotide sequence for human leukocyte interferon.

1980 • 128 citations

Influence of spatial configuration of carcinoma cell populations on the expression of a tumor-associated glycoprotein.

1985 • 125 citations

Interferon inhibits the conversion of 3T3-L1 mouse fibroblasts into adipocytes.

1980 • 121 citations

Human leukocyte interferon subtypes have different antiproliferative and antiviral activities on human cells

1983 • 119 citations

Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth.

1983 • 117 citations

Human melanoma cells can be killed in vitro by an immunotoxin specific for melanoma‐associated antigen p97

1982 • 116 citations

Interferon increases HLA synthesis in melanoma cells: interferon-resistant and -sensitive cell lines.

1982 • 115 citations

Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA

1983 • 109 citations

Effects of Combined Treatment with Interferon and Mezerein on Melanogenesis and Growth in Human Melanoma Cells

1985 • 105 citations

Molecular cloning and sequence of partial cDNA for interferon-induced (2'-5')oligo(A) synthetase mRNA from human cells.

1983 • 101 citations

Antiproliferative and antiviral activities of human leukocyte interferons

1981 • 97 citations

Structural Properties and Tissue Distribution of the Antigen Recognized by the Monoclonal Antibody 653.40S to Human Melanoma Cells<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 97 citations

A 94,OOO-Dalton Glycoprotein Expressed by Human Melanoma and Carcinoma Cells<xref ref-type="fn" rid="fn2">2</xref>

1982 • 96 citations

The amino-terminal sequence of human fibroblast interferon as deduced from reverse transcripts obtained using synthetic oligonucleotide primers

1980 • 93 citations

Immunologic Heterogeneity of Tumor Cell Subpopulations From a Single Mouse Mammary Tumor<xref ref-type="fn" rid="FN2">2</xref>

1979 • 93 citations

Effects of interferon on differentiation of normal and tumor cells

1985 • 86 citations

Human Interferon-γ Enhances the Expression of Class I and Class II Major Histocompatibility Complex Products in Neoplastic Cells More Effectively than Interferon-α and Interferon-β

1983 • 84 citations

Human Neoplastic and Normal Cells in Tissue Culture. I. Cell Lines Derived From Malignant Melanomas and Normal Melanocytes2

1976 • 81 citations

Differential effect of interferon on the expression of tumor-associated antigens and histocompatibility antigens on human melanoma cells: relationship to susceptibility to immune lysis mediated by monoclonal antibodies.

1981 • 80 citations

Differential Binding to Human Mammary and Nonmammary Tumors of Monoclonal Antibodies Reactive with Carcinoembryonic Antigen

1983 • 79 citations

Effects of recombinant and hybrid recombinant human leukocyte interferons on cytotoxic activity of natural killer cells.

1983 • 76 citations

Level of a membrane-bound high-molecular-weight melanoma-associated antigen and a cytoplasmic melanoma-associated antigen in surgically removed tissues and in sera from patients with melanoma.

1984 • 76 citations

Phenotyping of Lesions of Melanocyte Origin With Monoclonal Antibodies to Melanoma-Associated Antigens and to HLA Antigens<xref ref-type="fn" rid="FN2">2</xref>

1984 • 72 citations

Tissue distribution, molecular profile, and shedding of a cytoplasmic antigen identified by the monoclonal antibody 465.12S to human melanoma cells.

1982 • 72 citations

Enhancement of carcinoembryonic antigen expression by interferon

1979 • 70 citations

Current trends in tumor immunology

1979 • 63 citations

Structure of interferons

1985 • 63 citations

Opposing effects of interferon produced in bacteria and of tumor promoters on myogenesis in human myoblast cultures.

1983 • 56 citations

Tissue distribution and molecular profile of a differentiation antigen detected by a monoclonal antibody (345.134S) produced against human melanoma cells

1982 • 54 citations

Immunochemical characterization of a human high molecular weight ? melanoma associated antigen identified with monoclonal antibodies

1983 • 53 citations

Immunochemical analysis of the modulation of human melanoma-associated antigens by DNA recombinant immune interferon.

1985 • 53 citations

Interferon inhibits dimethyl sulphoxide-induced erythroid differentiation of Friend leukaemia cells

1977 • 52 citations

Monoclonal antibodies to breast cancer-associated antigens as potential reagents in the management of breast cancer

1984 • 47 citations

Enhanced Expression of Melanoma-Associated Antigens and β<sub>2</sub>-Microglobulin on Cultured Human Melanoma Cells by Interferon<xref ref-type="fn" rid="FN2">2</xref>

1982 • 45 citations

Recombinant human interferon sensitizes resistant myeloid leukemic cells to induction of terminal differentiation

1985 • 43 citations

Human Tumor Antigens: Detection and Characterization with Monoclonal Antibodies

1983 • 42 citations

Basic and Clinical Tumor Immunology

1983 • 40 citations

Antitumor Effects of Interferon

1977 • 40 citations

Differential effect of recombinant human leukocyte interferon on human leukemic and normal myeloid progenitor cells

1982 • 40 citations

Specific immunoassay for protein dimers, trimers, and higher oligomers

1983 • 37 citations

The impact of monoclonal antibodies on the study of human malignant melanoma

1983 • 35 citations

Monoclonal Antibodies Reactive With Breast Tumor-Associated Antigens

1985 • 33 citations

Interferon inhibits melanogenesis in b-16 mouse melanoma cells

1981 • 33 citations

Inhibition of adipose conversion of BALB/c 3T3 cells by interferon and 12-O-tetradecanoylphorbol-13-acetate

1980 • 30 citations

Differential responsiveness of cloned mammary carcinoma cell populations to the human recombinant leukocyte interferon enhancement of tumor antigen expression

1985 • 28 citations

Gene expression : the translational step and its control

1984 • 26 citations

Effect of recombinant human fibroblast interferon and mezerein on growth, differentiation, immune interferon binding and tumor associated antigen expression in human melanoma cells.

1986 • 23 citations

Selective in vitro toxicity of purothionin conjugated to the monoclonal antibody 225.28S to a human high-molecular-weight melanoma-associated antigen

1983 • 21 citations

Biosynthesis and intracellular processing of four human melanoma associated antigens.

1986 • 21 citations

A third polypeptide associated with heavy and light chain subunits of class I HLA antigens in immune interferon‐treated human melanoma cells

1985 • 19 citations

Hybrid recombinant human leukocyte interferon inhibits differentiation in murine B-16 melanoma cells

1984 • 18 citations

Somatic variants of the level of expression of a cell surface antigen.

1983 • 18 citations

A comparison of the antiproliferative and antiviral activities of α-, β- and γ-interferons: Description of a unified assay for comparing both effects simultaneously

1981 • 15 citations

Construction and identification of bacterial plasmids containing nucleotide sequence for human leukocyte interferon

1981 • 5 citations

The human interferons: from the past and into the future.

1984 • 5 citations