Human leukocyte interferon produced by E. coli is biologically active

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Virus interference. I. The interferon

1957 • 3,331 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

Construction and characterization of new cloning vehicles I. Ampicillin-resistant derivatives of the plasmid pMB9

1977 • 1,055 citations

The Interferon System

1979 • 1,035 citations

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event

1970 • 770 citations

Hybridization of synthetic oligodeoxyribonucleotides to Φ_X174 DNA: the effect of single base pair mismatch

1979 • 753 citations

Enhanced NK cell activity in mice injected with interferon and interferon inducers

1978 • 735 citations

Efficient transcription of RNA into DNA by avian sarcoma virus polymerase

1976 • 688 citations

Conservatism of the approximation sigma (O-E)2-E in the logrank test for survival data or tumor incidence data.

1973 • 672 citations

Acute Myelogenous Leukemia: A Human Cell Line Responsive to Colony-Stimulating Activity

1978 • 537 citations

Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone

1979 • 517 citations

352. Note: Conservatism of the Approximation Σ(O - E) 2 /E in the Logrank Test for Survival Data or Tumor Incidence Data

1973 • 503 citations

Synthesis in E. coli of a polypeptide with human leukocyte interferon activity

1980 • 484 citations

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

1978 • 426 citations

Construction of plasmids carrying the cI gene of bacteriophage lambda.

1976 • 410 citations

Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.

1978 • 395 citations

The Interferon System

1979 • 306 citations

[58] DNA sequence analysis by primed synthesis

1980 • 286 citations

Human leukocyte interferon: production, purification to homogeneity, and initial characterization.

1979 • 233 citations

Chemical synthesis of genes for human insulin.

1978 • 223 citations

Human Fibroblast Interferon: Amino Acid Analysis and Amino Terminal Amino Acid Sequence

1980 • 192 citations

Pronounced antiviral activity of human interferon on bovine and porcine cells

1974 • 174 citations

Detection and partial sequence analysis of gastrin mRNA by using an oligodeoxynucleotide probe.

1979 • 163 citations

The nucleotide sequence of a cloned human leukocyte Interferon cDNA

1980 • 158 citations

Amino Terminal Sequence of the Major Component of Human Lymphoblastoid Interferon

1980 • 156 citations

Translation of the leader region of the Escherichia coli tryptophan operon

1978 • 125 citations

Construction and identification of a bacterial plasmid containing the human fibroblast interferon gene sequence.

1979 • 93 citations

Synthesis of human interferon by Xenopus laevis oocytes: two structural genes for interferons in human cells.

1977 • 87 citations

Purification and partial characterization of human lymphoblast interferon.

1979 • 85 citations

Interferon activity produced by translation of human interferon messenger RNA in cell-free ribosomal systems and in Xenopus oöcytes.

1975 • 79 citations

Cell-free synthesis of human interferon.

1975 • 49 citations

Biosynthesis of mouse interferon by translation of its messenger RNA in a cell-free system.

1975 • 42 citations

Requirement for macrophages for interferon to be effective against encephalomyocarditis virus infection of mice

1978 • 26 citations