Human melanoma cells can be killed in vitro by an immunotoxin specific for melanoma‐associated antigen p97

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Antibodies to major histocompatibility antigens produced by hybrid cell lines

1977 • 1,727 citations

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

1979 • 466 citations

Human melanoma-associated antigen p97 is structurally and functionally related to transferrin

1982 • 288 citations

Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells

1981 • 275 citations

Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells.

1980 • 270 citations

Identification of a cell surface protein, p97, in human melanomas and certain other neoplasms.

1980 • 259 citations

Immunotoxins: hybrid molecules of monoclonal antibodies and a toxin subunit specifically kill tumour cells

1981 • 253 citations

Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling

1980 • 252 citations

Quantitative analysis of melanoma-associated antigen p97 in normal and neoplastic tissues.

1981 • 250 citations

Protides of the biological fluids—25th colloquium 1977

1979 • 206 citations

Structural characterization of human melanoma-associated antigen p97 with monoclonal antibodies.

1981 • 203 citations

Immunotoxins: Hybrid Molecules Combining High Specificity and Potent Cytotoxicity

1982 • 181 citations

Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin.

1980 • 168 citations

Selective Destruction of Target Cells by Diphtheria Toxin Conjugated to Antibody Directed against Antigens on the Cells

1970 • 162 citations

Monoclonal antibody-ricin A chain conjugate selectively cytotoxic for cells bearing the common acute lymphoblastic leukemia antigen.

1982 • 111 citations

Monoclonal Antibody‐Ricin or Ricin A Chain Hybrids: Kinetic Analysis of Cell Killing for Tumor Therapy

1982 • 109 citations

Specific cytotoxicity of a human immunoglobulin-directed Fab'-ricin A chain conjugate.

1980 • 65 citations

High specific cytotoxicity of antibody-toxin hybrid molecules (immunotoxins) for target cells

1980 • 60 citations

Preparation of a hybrid of fragment Fab' of antibody and fragment a of diphtheria toxin and its cytotoxicity

1979 • 55 citations

Monoclonal antibodies to two determinants of melanoma-antigen p97 act synergistically in complement-dependent cytotoxicity.

1981 • 55 citations

Increased Toxicity of Diphtheria Toxin for Human Lymphoblastoid Cells following Covalent Linkage to Anti-(human lymphocyte) Globulin or Its F(ab')2 Fragment

1980 • 45 citations

IMMUNOTHERAPY OF EXPERIMENTAL ANIMAL TUMORS WITH ANTITUMOR ANTIBODIES CONJUGATED TO DIPHTHERIA TOXIN OR RICIN*

1976 • 35 citations

The effect of abrin, anti-lymphocyte globulin and their conjugates on the immune response of mice to sheep red blood cells

1981 • 13 citations