The integrin α_Vβ₆ binds and activates latent TGFβ3

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1

1999 • 1,965 citations

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.

2000 • 1,945 citations

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis

2000 • 1,604 citations

Transforming growth factor–β3 is required for secondary palate fusion

1995 • 895 citations

An Assay for Transforming Growth Factor-β Using Cells Transfected with a Plasminogen Activator Inhibitor-1 Promoter-Luciferase Construct

1994 • 749 citations

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis

2000 • 415 citations

Normal embryo fibroblasts release transforming growth factors in a latent form

1984 • 336 citations

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.

1996 • 312 citations

Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.

1988 • 273 citations

Latency, activation, and binding proteins of TGF-?

2001 • 262 citations

Transforming growth factor-beta complexes with thrombospondin.

1992 • 256 citations

Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.

1994 • 250 citations

Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues.

1993 • 240 citations

Interactions between Growth Factors and Integrins: Latent Forms of Transforming Growth Factor-β Are Ligands for the Integrin αvβ1

1998 • 229 citations

Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion

1998 • 209 citations

Transforming growth factor β3 induces cell death during the first stage of mammary gland involution

2000 • 173 citations

The integrin αvβ6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin

1998 • 153 citations

Transforming growth factor-beta (beta 1, beta 2, and beta 3) gene expression and action during pubertal development of the seminiferous tubule: potential role at the onset of spermatogenesis.

1993 • 106 citations

Transforming growth factor-beta (beta 1, beta 2, and beta 3) gene expression and action during pubertal development of the seminiferous tubule: potential role at the onset of spermatogenesis

1993 • 56 citations

Integrin-Mediated Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis

2001 • 44 citations

Measurement of Active TGF-β Generated by Cultured Cells

2003 • 25 citations