Measurement of Active TGF-β Generated by Cultured Cells

A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1

1999 • 1,965 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

An Assay for Transforming Growth Factor-β Using Cells Transfected with a Plasminogen Activator Inhibitor-1 Promoter-Luciferase Construct

1994 • 749 citations

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

1988 • 648 citations

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

1988 • 647 citations

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

1991 • 521 citations

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

1990 • 466 citations

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

1990 • 449 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

1987 • 387 citations

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells.

1987 • 378 citations

Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions

1985 • 366 citations

Physicochemical Activation of Recombinant Latent Transforming Growth Factor-beta's 1, 2, and 3

1990 • 343 citations

Normal embryo fibroblasts release transforming growth factors in a latent form

1984 • 336 citations

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.

1989 • 333 citations

Identification of another member of the transforming growth factor type beta gene family.

1988 • 326 citations

Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts

1990 • 324 citations

Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta.

1991 • 324 citations

High specific activity iodination of gamma-globulin with iodine-131 monochloride.

1960 • 324 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.

1988 • 273 citations

TGF‐β Latency: Biological Significance and Mechanisms of Activation

1997 • 261 citations

Lipoprotein (a) inhibits the generation of transforming growth factor beta: an endogenous inhibitor of smooth muscle cell migration.

1991 • 232 citations

Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion

1998 • 209 citations

Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

1994 • 192 citations

A Factor from a Transformed Cell Line That Affects Cell Migration

1973 • 181 citations

Molecular cloning of the large subunit of transforming growth factor type beta masking protein and expression of the mRNA in various rat tissues.

1990 • 162 citations

Isolation of a Novel Latent Transforming Growth Factor-β Binding Protein Gene (LTBP-3)

1995 • 147 citations

Latent high molecular weight complex of transforming growth factor. beta. 1

1988 • 143 citations

Mechanism of retinoid‐induced activation of latent transforming growth factor‐β in bovine endothelial cells

1993 • 118 citations

Glucocorticoid-induced activation of latent transforming growth factor-beta by normal human osteoblast-like cells.

1993 • 112 citations

Sequence and expression of a novel member (LTBP‐4) of the family of latent transforming growth factor‐β binding proteins

1997 • 81 citations

Identification and activation of latent transforming growth factor β

1991 • 72 citations

Vitamin D₃and Calcipotriol Enhance the Secretion of Transforming Growth Factor-β1 and -β2 in Cultured Murine Keratinocytes

1993 • 54 citations

Mediation of glucocorticoid receptor function by the activation of latent transforming growth factor beta 1 in MG‐63 human osteosarcoma cells

1995 • 46 citations

Opposite and independent actions of cyclic AMP and transforming growth factor β in the regulation of type 1 plasminogen activator inhibitor expression

1992 • 32 citations

Plasminogen/Plasminogen Activator and Growth Factor Activation

2007 • 27 citations

Reduction of TGF‐beta activity abrogates growth promoting tumor cell‐cell interactions in vivo

1991 • 26 citations

Experiments with normal and transformed cells. A laboratory manual for working with cells in culture

1982 • 10 citations

Isotopic Assays for Reporter Gene Activity

2001 • 6 citations