B-lymphoma cells process and present their endogenous immunoglobulin to major histocompatibility complex-restricted T cells.

Towards a network theory of the immune system.

1974 • 3,379 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.

1983 • 701 citations

Establishment and Characterization of BALB/c Lymphoma Lines with B Cell Properties

1979 • 677 citations

Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.

1986 • 513 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

1979 • 451 citations

Direct transfer of cloned genes from bacteria to mammalian cells.

1980 • 291 citations

Class discrimination in the world of immunology

1987 • 214 citations

Idiotope‐specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules

1986 • 178 citations

Somatic variants of murine immunoglobulin λ light chains

1982 • 136 citations

Antigen Presentation by B Cells and Its Significance in T-B Interactions

1986 • 119 citations

Working principles in the immune system implied by the "peptidic self" model.

1987 • 115 citations

Cross‐blocking studies with monoclonal antibodies against I‐A molecules of haplotypes b, d and k

1982 • 81 citations

Synthetic peptides and β‐chain gene rearrangements reveal a diversified T cell repertoire for a λ light chain third hypervariable region

1986 • 61 citations

Helper T cell recognition of the variable domains of a mouse myeloma protein (315). Effect of the major histocompatibility complex and domain conformation.

1982 • 54 citations

T helper cell recognition of idiotopes on λ2 light chains of M315 and T952: evidence for dependence on somatic mutations in the third hypervariable region

1985 • 51 citations

The T lymphocyte response to syngeneic λ2 light chain idiotopes. Significance of individual amino acids revealed by variant λ2 chains and idiotope-mimicking chemically synthesized peptides

1986 • 36 citations

T cell clones specific for IgG2a of the a allotype: direct evidence for presentation of endogenous antigen.

1986 • 34 citations

Direct interactions between B and T lymphocytes bearing complementary receptors.

1986 • 34 citations

Nucleotide sequence of a chromosomal rearranged λ₂immunoglobulin gene of mouse

1982 • 31 citations

Cytotoxic T lymphocyte clone recognizing self idiotype: its regulatory role in antibody production

1987 • 30 citations

Recognition of λ1 and λ2 murine light chains by carrierspecific isologous T helper cells; effect of L‐H chain assembly

1983 • 23 citations

Human anti-idiotypic T lymphocyte clones are activated by autologous anti-rabies virus antibodies presented in association with HLA-DQ molecules.

1987 • 9 citations

A cloned T cell line that selectively augments antibody responses of phosphorylcholine-specific B cells bearing the T15 idiotype.

1986 • 7 citations