Immunoglobulin flexibility in complement activation

Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 Å and 1.9 Å resolution

1980 • 455 citations

Immunoglobulin G: Functional sites

1985 • 442 citations

Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments

1979 • 329 citations

Correlation between segmental flexibility and effector function of antibodies

1984 • 235 citations

Activation of mouse complement by monoclonal mouse antibodies

1981 • 226 citations

The reaction of monomeric and aggregated immunoglobulins with Cl

1971 • 225 citations

Structure and function of the constant regions of immunoglobulins

1976 • 206 citations

Structure and Function of γ Macroglobulins

1970 • 206 citations

Hemolysin Titration Based on Fixation of the Activated First Component of Complement: Evidence That One Molecule of Hemolysin Suffices to Sensitize an Erythrocyte

1965 • 185 citations

Molecular Mechanism of Formation of an Antigen–Antibody Complex

1965 • 184 citations

The structure and function of immunoglobulin domains. IV. The distribution of some effector functions among the Cgamma2 and Cgamma3 homology regions of human immunoglobulin G1.

1976 • 165 citations

The C1q receptor site on immunoglobulin G

1980 • 161 citations

Initiation of complement activation

1984 • 160 citations

Ultracentrifuge studies of the binding of IgG of different subclasses to the Clq subunit of the first component of complement

1976 • 159 citations

The structure and function of immunoglobulin domains. II. The importance of interchain disulfide bonds and the possible role of molecular flexibility in the interaction between immunoglobulin G and complement.

1975 • 154 citations

Structure of the human antibody molecule kol (immunoglobulin G1): An electron density map at 5 Å resolution

1976 • 148 citations

The Effect of Antigen on Antibodies: Recent Studies

1978 • 142 citations

Conformation of the Free and Antigen-bound IgM Antibody Molecules

1969 • 139 citations

Characterization of a plasmin-digest fragment of rabbit immunoglobulin gamma that binds antigen and complement

1975 • 126 citations

Immunoglobulin structure and effector functions

1978 • 111 citations

The Structure and Function of Immunoglobulin Domains

1976 • 107 citations

THE THREE‐DIMENSIONAL CONFORMATION OF γ M and γ A GLOBULIN MOLECULES

1971 • 99 citations

The Structure and Function of Immunoglobulin Domains

1975 • 87 citations

The three-dimensional structure of antibodies

1982 • 74 citations

Functional affinity constants of the reaction between 125I-labelled C1q and C1q binders and their use in the measurement of plasma C1q concentrations.

1977 • 71 citations

Fixation of C' and C'la by rabbit gamma-G- and gamma-M-antibodies with particulate and soluble antigens.

1968 • 59 citations

Crystallographic Structural Studies of a Human Fc-Fragment. I. An Electron-Density Map at 4 Å Resolution and a Partial Model

1976 • 57 citations

Binding of complement subcomponent Clq to mouse IgGl, IgG2a AND IgG2b: A novel Clq binding assay

1984 • 51 citations

Inhibition of C1-mediated immune hemolysis by monomeric and dimeric peptides from the second constant domain of human immunoglobulin G.

1981 • 44 citations

Fixation of C′ and C′la by Rabbit γG- and γM-Antibodies with Particulate and Soluble Antigens

1968 • 43 citations

MAPPING OF THE COMBINING SITES OF ANTIBODIES SPECIFIC TO POLYALANINE CHAINS

1971 • 41 citations

Binding sites for Fcγ receptors on immunoglobulin G and factors influencing their expression

1982 • 33 citations

Immunochemistry: An advanced textbook

1978 • 32 citations

Protein conformation as an immunological signal

1984 • 26 citations

Chemical verification of the C1q receptor site on IgG

1982 • 13 citations

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