αLβ2 Integrin/LFA-1 Binding to ICAM-1 Induced by Cytohesin-1, a Cytoplasmic Regulatory Molecule

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Current protocols in molecular biology

1988 • 7,584 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Protein modules and signalling networks

1995 • 2,447 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1993 • 1,531 citations

Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

1996 • 1,106 citations

Recognition by Elam-1 of the Sialyl-Le ^x Determinant on Myeloid and Tumor Cells

1990 • 976 citations

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

1985 • 968 citations

Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice

1993 • 868 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

Integrin cytoplasmic domains mediate inside-out signal transduction

1994 • 682 citations

Physiological and Molecular Mechanisms of Lymphocyte Homing

1992 • 655 citations

ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM

1988 • 631 citations

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.

1995 • 569 citations

The PH domain: a common piece in the structural pathcwork of signalling proteins

1993 • 536 citations

Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion

1991 • 532 citations

A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.

1993 • 523 citations

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1989 • 482 citations

The dynamic regulation of integrin adhesiveness

1994 • 456 citations

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1993 • 447 citations

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

1991 • 391 citations

T cell activation by clustered tyrosine kinases

1993 • 379 citations

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

1992 • 361 citations

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes.

1995 • 355 citations

Modulation of the Affinity of Integrin α _IIb β ₃ (GPIIb-IIIa) by the Cytoplasmic Domain of α _IIb

1991 • 322 citations

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.

1994 • 322 citations

Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits.

1989 • 321 citations

EMB30 is essential for normal cell division, cell expansion, and cell adhesion in Arabidopsis and encodes a protein that has similarity to Sec7

1994 • 313 citations

Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domains

1992 • 307 citations

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1992 • 306 citations

Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.

1990 • 285 citations

Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynamin

1994 • 268 citations

Ins and outs of LFA-1

1995 • 260 citations

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18.

1995 • 252 citations

The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site.

1991 • 241 citations

Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.

1994 • 240 citations

Expression and function of chicken integrin beta 1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells.

1990 • 238 citations

Structure of the pleckstrin homology domain from β-spectrin

1994 • 233 citations

Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytes.

1988 • 230 citations

Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion.

1991 • 223 citations

Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase

1986 • 205 citations

The Conserved Membrane-proximal Region of an Integrin Cytoplasmic Domain Specifies Ligand Binding Affinity

1995 • 202 citations

Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit.

1995 • 187 citations

Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.

1993 • 187 citations

“Inside-out” signal transduction inhibited by isolated integrin cytoplasmic domains

1994 • 177 citations

Modulation of cell adhesion by changes in alpha L beta 2 (LFA-1, CD11a/CD18) cytoplasmic domain/cytoskeleton interaction.

1995 • 167 citations

Extracellular Ca2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion

1994 • 148 citations

SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.

1988 • 145 citations

Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.

1995 • 136 citations

A novel LFA-1 activation epitope maps to the I domain.

1993 • 136 citations

Ins and outs

1994 • 109 citations

Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin.

1993 • 100 citations

Contrasting roles for integrin beta 1 and beta 5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration.

1994 • 97 citations

Cloning and sequencing of a human cDNA from cytolytic NK/T cells with homology to yeast SEC7

1992 • 63 citations

A beta turn in the cytoplasmic tail of the integrin alpha v subunit influences conformation and ligand binding of alpha v beta 3.

1994 • 57 citations

Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.

1990 • 37 citations

Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen.

1986 • 20 citations

LFA-1 integrin redistribution during T-cell hybridoma invasion of hepatocyte cultures and manganese-induced adhesion to ICAM-1

2000 • 14 citations

Immuno-EM localization of the β1integrin subunit in wet-cleaved fibronectin-adherent fibroblasts

1994 • 5 citations