Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

1985 • 968 citations

Platelet Membrane Glycoprotein IIb/IIIa: Member of a Family of Arg-Gly-Asp—Specific Adhesion Receptors

1986 • 945 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

Human platelets possess an inducible and saturable receptor specific for fibrinogen.

1979 • 713 citations

Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen.

1988 • 374 citations

Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.

1980 • 373 citations

Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells

1989 • 343 citations

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

1990 • 328 citations

The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit.

1990 • 316 citations

Cytoadhesins, Integrins, and Platelets

1988 • 306 citations

Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion.

1988 • 280 citations

Aggregation of complement receptors on human neutrophils in the absence of ligand.

1987 • 250 citations

A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.

1988 • 248 citations

Induction of the fibrinogen receptor on human platelets by intracellular mediators.

1987 • 240 citations

Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets.

1987 • 222 citations

A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen

1989 • 213 citations

Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

1986 • 206 citations

Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombasthenia

1980 • 161 citations

Up-regulation of the iC3b receptor (CR3) is neither necessary nor sufficient to promote neutrophil aggregation.

1988 • 161 citations

Efficient surface expression of platelet GPIIb-IIIa requires both subunits

1989 • 158 citations

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.

1986 • 152 citations

Platelet activation by CD9 monoclonal antibodies is mediated by the F_CγII receptor

1990 • 136 citations

The activation of human platelets mediated by anti-human platelet p24/CD9 monoclonal antibodies.

1990 • 134 citations

Redistribution of the fibrinogen receptor of human platelets after surface activation.

1984 • 133 citations

Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa.

1987 • 133 citations

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits.

1987 • 131 citations

Characteristics of platelet aggregation induced by the monoclonal antibody ALB₆ (acute lymphoblastic leukemia antigen p 24)

1983 • 116 citations

The mechanism of thrombin-induced platelet factor 4 secretion

1980 • 104 citations

Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.

1985 • 100 citations

Activation affects access to the platelet receptor for adhesive glycoproteins.

1986 • 93 citations

Expression of recombinant platelet glycoprotein IIbIIIa results in a functional fibrinogen-binding complex

1989 • 90 citations

Fibrinogen receptor exposure and aggregation of human blood platelets produced by ADP and chilling

1981 • 83 citations

Identification of a monoclonal antibody against platelet GPIIb that interacts with a calcium-binding site and induces aggregation.

1990 • 71 citations

The leukocyte integrin LFA-1 reconstituted by cDNA transfection in a nonhematopoietic cell line is functionally active and not transiently regulated.

1990 • 64 citations

Fibrinogen receptor exposure and aggregation of human blood platelets produced by ADP and chilling

1981 • 55 citations

Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombasthenia

1980 • 31 citations

The mechanism of thrombin-induced platelet factor 4 secretion

1980 • 9 citations