Reverse transformation of multidrug-resistant cells

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1976 • 3,228 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

1973 • 1,284 citations

Glycosyltransferases

1989 • 904 citations

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

1985 • 843 citations

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.

1970 • 752 citations

Biosynthesis and Function of Gangliosides

1976 • 748 citations

Transposition and amplification of oncogene-related sequences in human neuroblastomas

1983 • 711 citations

Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.

1986 • 702 citations

Reduced permeability in CHO cells as a mechanism of resistance to colchicine

1974 • 695 citations

Glycosphingolipids as Tumor-Associated and Differentiation Markers<xref ref-type="fn" rid="FN5">5</xref><xref ref-type="fn" rid="FN6">6</xref>

1983 • 580 citations

Coordinate Morphological and Biochemical Interconversion of Human Neuroblastoma Cells<xref ref-type="fn" rid="FN2">2</xref>

1983 • 544 citations

Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts.

1979 • 478 citations

Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages.

1989 • 466 citations

Metaphase Chromosome Anomaly: Association with Drug Resistance and Cell-Specific Products

1976 • 396 citations

Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability.

1979 • 368 citations

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

1984 • 340 citations

Role of epidermal growth factor in carcinogenesis.

1986 • 330 citations

Advances in neuroblastoma research

1980 • 325 citations

Important Advances in Oncology 1989

1990 • 304 citations

Amplification and Expression of Genes Associated with Multidrug Resistance in Mammalian Cells

1986 • 293 citations

Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells

1991 • 281 citations

Relation of Folic Acid Reductase to Amethopterin Resistance in Cultured Mammalian Cells

1961 • 210 citations

Drug Resistance in Oncology

1994 • 173 citations

Uptake and retention of daunomycin by mouse leukemic cells as factors in drug response.

1968 • 171 citations

Genes amplified and overexpressed in human multidrug-resistant cell lines.

1988 • 170 citations

Coordinate changes in neuronal phenotype and surface antigen expression in human neuroblastoma cell variants.

1987 • 159 citations

Alteration of plasma membrane glycopeptides and gangliosides of Chinese hamster cells accompanying development of resistance to daunorubicin and vincristine.

1983 • 146 citations

Gangliosides and glycosphingolipids as modulators of cell growth, adhesion, and transmembrane signaling.

1993 • 137 citations

Mammalian glycosyltransferases: genomic organization and protein structure

1992 • 135 citations

Multidrug resistance mediated by P-glycoproteins.

1991 • 113 citations

Cellular resistance to daunomycin in Chinese hamster cells in vitro.

1971 • 113 citations

Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines.

1986 • 113 citations

Presence and regulation of tyrosinase activity in human neuroblastoma cell variants in vitro.

1985 • 110 citations

Membrane-Mediated Drug Resistance and Phenotypic Reversion to Normal Growth Behavior of Chinese Hamster Cells 2

1975 • 106 citations

Drug resistance in Chinese hamster lung and mouse tumor cells.

1983 • 105 citations

Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells.

1985 • 100 citations

Increased epidermal growth factor receptor in multidrug‐resistant human neuroblastoma cells

1988 • 98 citations

Amplification of Dihydrofolate Reductase Genes in Methotrexate-resistant Cultured Mouse Cells

1978 • 93 citations

Advances in Neuroblastoma Research

1987 • 78 citations

Genetic aspects of multidrug resistance

1992 • 77 citations

Drug resistance: genotype versus phenotype--thirty-second G. H. A. Clowes Memorial Award Lecture.

1994 • 75 citations

Plasma membrane proteins and glycoproteins from chinese hamster cells sensitive and resistant to actinomycin D

1978 • 66 citations

Epidermal growth factor receptor is increased in multidrug-resistant Chinese hamster and mouse tumor cells.

1986 • 65 citations

Incorporation of Tritiated Actinomycin D into Drug-Sensitive and Drug-Resistant HeLa Cells

1966 • 63 citations

Genetic and enzymatic basis for the differential expression of GM2 and GD2 gangliosides in human cancer cell lines.

1993 • 58 citations

Transdifferentiation of human neuroblastoma cells results in coordinate loss of neuronal and malignant properties.

1988 • 55 citations

Drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant Chinese hamster cells in vitro.

1972 • 52 citations

Alpha‐smooth‐muscle actin and desmin expressions in human neuroblastoma cell lines

1991 • 40 citations

SOME BIOCHEMICAL PROPERTIES OF CHINESE HAMSTER CELLS SENSITIVE AND RESISTANT TO ACTINOMYCIN D

1974 • 39 citations

Over‐expression of MDR gene with no dna amplification in a multiple‐drug‐resistant human ovarian carcinoma cell line

1989 • 36 citations

Multidrug resistance in human neuroblastoma cells

1991 • 32 citations

Biochemical and karyological properties of cells resistant to the quinazoline antifolate, methasquin

1978 • 31 citations

The multidrug resistance phenotype in human cancer.

1991 • 31 citations

Differential Amplification and Disproportionate Expression of Five Genes in Three Multidrug-Resistant Chinese Hamster Lung Cell Lines

1986 • 24 citations

GANGLIOSIDE PATTERNS AND PHENOTYPIC CHARACTERISTICS IN A NORMAL VARIANT AND A TRANSFORMED BACK VARIANT OF A SIMIAN VIRUS 40-INDUCED HAMSTER TUMOR CELL LINE

1973 • 24 citations

Cytogenetic and molecular characterization of tumors in nude mice derived from a multidrug-resistant human leukemia cell line.

1988 • 23 citations

Multistep change in epidermal growth factor receptors during spontaneous neoplastic progression in Chinese hamster embryo fibroblasts.

1985 • 23 citations

Cellular Concomitants of Multidrug Resistance

1988 • 19 citations

Actinomycin‐D‐resistant in vitro mouse cell line derived from a methylcholanthrene‐induced sarcoma: Decrease of malignancy and antigenic characteristics

1974 • 17 citations

Differentiation and the multiple drug resistance phenotype in human leukemic cells.

1986 • 17 citations

Multidrug-resistant human neuroblastoma cells are more differentiated than controls and retinoic acid further induces lineage-specific differentiation.

1991 • 16 citations

Ganglioside composition of malignant and actinomycin D-resistant nonmalignant Chinese hamster cells

1979 • 16 citations

Molecular and Cytogenetic Analysis of Multidrug Resistance-Associated Gene Amplification in Chinese Hamster, Mouse Sarcoma, and Human Neuroblastoma Cells

1991 • 15 citations

Differentiation-inducing agents stably convert human neuroblastoma I-type cells to neuroblastic (N) or nonneuronal (S) neural crest cells.

1994 • 14 citations

Properties of an SV40‐transformed hamster cell line resistant to actinomycin D

1972 • 13 citations

Collagen Biosynthesis in Human Neuroblastoma Cell Lines: Evidence for Expression of Glial Cell Properties<xref ref-type="fn" rid="FN2">2</xref>

1985 • 10 citations

Multipotent capacity of morphologically intermediate (I-type) human neuroblastoma cells after treatment with differentiation-inducing drugs.

1991 • 10 citations

Amplification of Several Different Genes in Multidrug-Resistant Chinese Hamster Cell Lines

1991 • 10 citations

Evidence for reverse transformation in multidrug-resistant human neuroblastoma cells.

1988 • 9 citations

Cellular maturation and oncogene expression during drug-induced differentiation in vitro: a brief review.

1990 • 7 citations

Protein Changes in Multidrug-Resistant Cells

1991 • 4 citations

Deleted Work

1955 • 0 citations