Over‐expression of MDR gene with no dna amplification in a multiple‐drug‐resistant human ovarian carcinoma cell line

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Use of Ranks in One-Criterion Variance Analysis

1952 • 9,960 citations

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1976 • 3,228 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

1977 • 1,743 citations

Expression of a multidrug-resistance gene in human tumors and tissues.

1987 • 1,547 citations

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

1983 • 921 citations

The cloning of normal “Mast” cells in tissue culture

1965 • 886 citations

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

1985 • 843 citations

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.

1970 • 752 citations

Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates

1986 • 678 citations

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

1986 • 561 citations

Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines.

1985 • 441 citations

The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

1986 • 410 citations

The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation.

1987 • 384 citations

The cell biology of multiple drug resistance

1987 • 340 citations

Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancer cells.

1987 • 296 citations

Characterization of a human ovarian adenocarcinoma line, IGROV1, in tissue culture and in nude mice.

1985 • 296 citations

Localization of insulin-like growth factor genes to human chromosomes 11 and 12

1984 • 180 citations

Pharmacological and biological evidence for differing mechanisms of doxorubicin resistance in two human tumor cell lines.

1988 • 154 citations

Promotion by verapamil of vincristine responsiveness in tumor cell lines inherently resistant to the drug.

1983 • 119 citations

Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene.

1985 • 117 citations

Implication of chromosome 11 in the suppression of neoplastic expression in human cell hybrids.

1986 • 108 citations

Membrane-Mediated Drug Resistance and Phenotypic Reversion to Normal Growth Behavior of Chinese Hamster Cells 2

1975 • 106 citations

Drug resistance in Chinese hamster lung and mouse tumor cells.

1983 • 105 citations

Advances in Neuroblastoma Research

1987 • 78 citations

Epidermal growth factor receptor is increased in multidrug-resistant Chinese hamster and mouse tumor cells.

1986 • 65 citations

Nonrandom chromosomal changes in human solid tumors: application of an improved culture method.

1987 • 58 citations

Verapamil hypersensitivity of vincristine resistant Chinese hamster ovary cell lines

1986 • 51 citations

Cytogenetic and molecular characterization of tumors in nude mice derived from a multidrug-resistant human leukemia cell line.

1988 • 23 citations

Actinomycin‐D‐resistant in vitro mouse cell line derived from a methylcholanthrene‐induced sarcoma: Decrease of malignancy and antigenic characteristics

1974 • 17 citations

The use of an image analyser in human tumour clonogenic assays

1986 • 14 citations

Expression of human chromosome 11-encoded cell-surface antigens by DNA-mediated transfectants

1986 • 9 citations