Determinants of the calcium permeation of ligand-gated cation channels

Ion Channels/Excitable Membranes

2006 • 2,013 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1991 • 1,465 citations

Ca2 ⁺ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

1991 • 1,458 citations

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1992 • 1,077 citations

Primary Structure And Functional Expression of the 5HT ₃ Receptor, A Serotonin-gated Ion Channel

1991 • 976 citations

Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

1987 • 934 citations

Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels

1991 • 827 citations

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

1988 • 798 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1991 • 515 citations

Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. Evidence for a hetero-oligomeric structure in rat brain.

1992 • 505 citations

Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones.

1990 • 498 citations

Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors

1992 • 465 citations

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

1991 • 463 citations

The aromatic binding site for tetraethylammonium ion on potassium channels

1992 • 446 citations

Molecular Neurobiology of Glutamate Receptors

1992 • 436 citations

Evidence That the M2 Membrane-Spanning Region Lines the Ion Channel Pore of the Nicotinic Receptor

1988 • 379 citations

The structure of ion channels in membranes of excitable cells

1989 • 368 citations

[23] Progressive alignment and phylogenetic tree construction of protein sequences

1990 • 350 citations

Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation

1992 • 328 citations

Functional Architecture of the Nicotinic Acetylcholine Receptor: From Electric Organ to Brain

1991 • 327 citations

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

1990 • 275 citations

Subunit promiscuity among hemopoietic growth factor receptors

1991 • 273 citations

Nicotinic acetylcholine receptor and superfamily of ligand-gated ion channels

1990 • 260 citations

Biochemical Characterization and Localization of a Non‐N‐Methyl‐D‐Aspartate Glutamate Receptor in Rat Brain

1992 • 242 citations

Agonist-activated cobalt uptake identifies divalent cation—Permeable kainate receptors on neurons and glial cells

1991 • 214 citations

Permeation of Calcium Ions Through Non-NMDA Glutamate Channels in Retinal Bipolar Cells

1991 • 209 citations

Potentiation of nicotinic receptor response by external calcium in rat central neurons

1992 • 191 citations

Structural determinants of barium permeation and rectification in non- NMDA glutamate receptor channels

1992 • 180 citations

Both NMDA and non-NMDA subtypes of glutamate receptors are concentrated at synapses on cerebral cortical neurons in culture

1991 • 172 citations

Nicotine receptors in the mammalian brain

1990 • 149 citations

Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel

1991 • 127 citations

Explorations of the nicotinic acetylcholine receptor.

1989 • 113 citations

[41] Nearest neighbor procedure for relating progressively aligned amino acid sequences

1990 • 107 citations

The Nicotinic Receptor Genes

1991 • 39 citations

In the GluR1 glutamate receptor subunit a glutamine to histidine point mutation suppresses inward rectification but not calcium permeability

1992 • 23 citations

STRATEGIES FOR STUDYING PERMEATION AT VOLTAGE-GATED ION CHANNELS

1991 • 21 citations