Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site

Mitochondria and Apoptosis

1998 • 8,909 citations

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 • 4,043 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

Identification and characterization of a new member of the TNF family that induces apoptosis

1995 • 2,890 citations

A model for p53-induced apoptosis

1997 • 2,502 citations

Definition of a consensus binding site for p53

1992 • 2,000 citations

The p53-mdm-2 autoregulatory feedback loop.

1993 • 1,795 citations

Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

1996 • 1,793 citations

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1997 • 1,694 citations

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

1997 • 1,506 citations

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1993 • 1,445 citations

Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen

1994 • 941 citations

p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer Drugs

1998 • 857 citations

The Novel Receptor TRAIL-R4 Induces NF-κB and Protects against TRAIL-Mediated Apoptosis, yet Retains an Incomplete Death Domain

1997 • 829 citations

Regulation ofp53downstream genes

1998 • 777 citations

Death Receptor 5, a New Member of the TNFR Family, and DR4 Induce FADD-Dependent Apoptosis and Activate the NF-κB Pathway

1997 • 685 citations

A novel receptor for Apo2L/TRAIL contains a truncated death domain

1997 • 650 citations

Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family

1997 • 634 citations

Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

1997 • 566 citations

Cyclin G is a transcriptional target of the p53 tumor suppressor protein.

1994 • 450 citations

Sequence-specific transcriptional activation is essential for growth suppression by p53.

1994 • 412 citations

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

1997 • 331 citations

Characterization of two receptors for TRAIL¹

1997 • 293 citations

A functional p53-responsive intronic promoter is contained within the humanmdm2gene

1995 • 271 citations

Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

1999 • 236 citations

Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity

1998 • 229 citations

Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting regionSelfcloseTable

1997 • 169 citations

Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes.

1993 • 152 citations

The TRAIL Decoy Receptor TRUNDD (DcR2, TRAIL-R4) Is Induced by Adenovirus-p53 Overexpression and Can Delay TRAIL-, p53-, and KILLER/DR5-Dependent Colon Cancer Apoptosis

2000 • 114 citations

Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest

1999 • 111 citations

Cutting Edge: Lymphocyte Inhibitor of TRAIL (TNF-Related Apoptosis-Inducing Ligand): A New Receptor Protecting Lymphocytes from the Death Ligand TRAIL

1998 • 104 citations

Identification of an additional p53-responsive site in the human epidermal growth factor receptor gene promotor

1997 • 48 citations

Detection and Analysis of Living, Growth-Inhibited Mammalian Cells Following Transfection

1997 • 12 citations