A Developmentally Regulated, Neuron-specific Splice Variant of the Variable Subunit Bβ Targets Protein Phosphatase 2A to Mitochondria and Modulates Apoptosis
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References (48)
Antibodies, a laboratory manual
1989 • 12,929 citations
The expanding role of mitochondria in apoptosis.
2001 • 2,377 citations
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001 • 1,654 citations
Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases
1991 • 1,327 citations
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001 • 1,268 citations
Sex, stress and the hippocampus: allostasis, allostatic load and the aging process
2002 • 725 citations
Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A
1999 • 423 citations
Regulation of the Phosphorylation State and Microtubule-Binding Activity of Tau by Protein Phosphatase 2A
1996 • 389 citations
Ceramide Induces Bcl2 Dephosphorylation via a Mechanism Involving Mitochondrial PP2A
1999 • 340 citations
Protein Insertion into the Mitochondrial Inner Membrane by a Twin-Pore Translocase
2003 • 316 citations
A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle.
1995 • 305 citations
Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits
2002 • 268 citations
A system for characterizing cellular and molecular events in programmed neuronal cell death
1993 • 267 citations
Molecular Glue: Kinase Anchoring and Scaffold Proteins
1996 • 264 citations
[18] PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation
1987 • 243 citations
Nicotinic Receptor-Induced Apoptotic Cell Death of Hippocampal Progenitor Cells
1998 • 234 citations
[33] Classification of protein- serine/threonine phosphatases: identification and quantitation in cell extracts
1991 • 223 citations
Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics
2002 • 217 citations
B cell receptor-associated protein α4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A
1997 • 212 citations
Cyclin G2 Associates with Protein Phosphatase 2A Catalytic and Regulatory B′ Subunits in Active Complexes and Induces Nuclear Aberrations and a G1/S Phase Cell Cycle Arrest
2002 • 210 citations
Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform
1991 • 206 citations
Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits
1998 • 175 citations
NH2-Terminal Targeting Motifs Direct Dual Specificity A-Kinase–anchoring Protein 1 (D-AKAP1) to Either Mitochondria or Endoplasmic Reticulum
1999 • 168 citations
Separation of PP2A Core Enzyme and Holoenzyme with Monoclonal Antibodies against the Regulatory A Subunit: Abundant Expression of Both Forms in Cells
1997 • 164 citations
Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene.
1996 • 163 citations
Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3–dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation
2001 • 151 citations
A Functional Role for the B56 α-Subunit of Protein Phosphatase 2A in Ceramide-mediated Regulation of Bcl2 Phosphorylation Status and Function
2002 • 149 citations
Mitochondria-Targeting Sequence, a Multi-Role Sorting Sequence Recognized at All Steps of Protein Import into Mitochondria
1998 • 146 citations
Organelle-specific Targeting of Protein Kinase AII (PKAII)
1997 • 145 citations
B56-Associated Protein Phosphatase 2A Is Required For Survival and Protects from Apoptosis in Drosophila melanogaster
2002 • 136 citations
PR48, a Novel Regulatory Subunit of Protein Phosphatase 2A, Interacts with Cdc6 and Modulates DNA Replication in Human Cells
2000 • 117 citations
Molecular and clinical correlation in five Indian families with spinocerebellar ataxia 12
2001 • 107 citations
Cardiolipin: biosynthesis, remodeling and trafficking in the heart and mammalian cells (Review).
1998 • 107 citations
Essential Role of A-kinase Anchor Protein 121 for cAMP Signaling to Mitochondria
2003 • 103 citations
Vimentin Dephosphorylation by Protein Phosphatase 2A Is Modulated by the Targeting Subunit B55
1999 • 100 citations
Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein
1999 • 99 citations
Protein phosphatase 2A is required for the initiation of chromosomal DNA replication
1998 • 90 citations
Targeting of hexokinase 1 to liver and hepatoma mitochondria.
1992 • 87 citations
Identification and Functional Analysis of Two Ca2+-binding EF-hand Motifs in the B“/PR72 Subunit of Protein Phosphatase 2A
2003 • 85 citations
Constant Expression and Activity of Protein Phosphatase 2A in Synchronized Cells
1991 • 84 citations
Protein Phosphatase 2A Holoenzyme Assembly
2002 • 84 citations
Cloning and characterization of Bδ, a novel regulatory subunit of protein phosphatase 2A
1999 • 81 citations
Overexpression of the Protein Phosphatase 2A Regulatory Subunit Bγ Promotes Neuronal Differentiation by Activating the MAP Kinase (MAPK) Cascade
2002 • 80 citations
Inhibition of the Wnt Signaling Pathway by the PR61 Subunit of Protein Phosphatase 2A
2001 • 68 citations
Interaction between Protein Phosphatase 5 and the A subunit of Protein Phosphatase 2A
2001 • 63 citations
Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A
2002 • 54 citations
Expression of PP2A B regulatory subunit β isotype in rat testis
1993 • 34 citations
Protein Phosphatase 2A Regulatory Subunits
1998 • 5 citations