Targeting of hexokinase 1 to liver and hepatoma mitochondria.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

Construction of plasmids that expressE.coli β-galactosidase in mammalian cells

1989 • 458 citations

Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.

1988 • 313 citations

Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC

1986 • 210 citations

Identification and characterization of the pore-forming protein in the outer membrane of rat liver mitochondria

1982 • 184 citations

Purification of a hexokinase-binding protein from the outer mitochondrial membrane.

1979 • 161 citations

Purification and properties of rat brain hexokinase

1972 • 151 citations

The cationically selective state of the mitochondrial outer membrane pore: a study with intact mitochondria and reconstituted mitochondrial porin

1990 • 147 citations

Porin interaction with hexokinase and glycerol kinase: Metabolic microcompartmentation at the outer mitochondrial membrane

1991 • 136 citations

Expression of Liver Phenotypes in Cultured Mouse Hepatoma Cells<xref ref-type="fn" rid="FN2">2</xref>

1980 • 134 citations

An intact hydrophobic N-terminal sequence is critical for binding of rat brain hexokinase to mitochondria

1985 • 131 citations

Porin pores of mitochondrial outer membranes from high and low eukaryotic cells: biochemical and biophysical characterization

1987 • 127 citations

Glucose phosphorylation in tumor cells. Cloning, sequencing, and overexpression in active form of a full-length cDNA encoding a mitochondrial bindable form of hexokinase.

1990 • 118 citations

Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase.

1989 • 110 citations

Human hexokinase: Sequences of amino- and carboxyl-terminal halves are homologous

1988 • 100 citations

Compartmentation of Hexokinase and Creatine Phosphokinase, Cellular Regulation, and Insulin Action

1980 • 87 citations

The 35 kDa DCCD-binding protein from pig heart mitochondria is the mitochondrial porin

1985 • 87 citations

The mitochondrial outer membrane channel, VDAC, is modulated by a soluble protein

1988 • 85 citations

Complete amino acid sequence of the type II isozyme of rat hexokinase, deduced from the cloned cDNA: Comparison with a hexokinase from novikoff ascites tumor

1991 • 83 citations

Pore formation by the mitochondrial porin of rat brain in lipid bilayer membranes

1986 • 64 citations

Human glycerol kinase deficiency: An inborn error of compartmental metabolism

1983 • 63 citations

Rat brain hexokinase: A kinetic comparison of soluble and particulate forms

1970 • 61 citations

Interaction of mitochondrial porin with cytosolic proteins

1990 • 44 citations

Ligand-lnduced conformations of rat brain hexokinase: Effects of glucose-6-phosphate and inorganic phosphate

1973 • 42 citations

Insulin effect on [14C]-valine incorporation and its relation to hexokinase activity in developing brain

1988 • 10 citations

Upstream DNA sequences determine different autoregulatory responses of the adenovirus types 5 and 3 E1A promoters

1989 • 7 citations