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Recent developments in transferred NOE methods

Data up to Jan 2025

Published1994
Citations273
References210

Total Citations Per Year

Abstract

References (210)

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A theoretical study of distance determinations from NMR. Two-dimensional nuclear overhauser effect spectra

1984 • 445 citations

An evaluation of computational strategies for use in the determination of protein structure from distance constraints obtained by nuclear magnetic resonance

1991 • 426 citations

Improved solvent suppression in one- and two-dimensional NMR spectra by convolution of time-domain data

1989 • 403 citations

Theory and applications of the transferred nuclear overhauser effect to the study of the conformations of small ligands bound to proteins

1982 • 392 citations

A general two-site solution for the chemical exchange produced dependence of T2 upon the carr-Purcell pulse separation

1972 • 384 citations

Truncated driven nuclear overhauser effect (TOE). A new technique for studies of selective 1H1H overhauser effects in the presence of spin diffusion

1979 • 355 citations

Heteronuclear filters in two-dimensional [1H, 1H]-NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

1990 • 354 citations

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1980 • 341 citations

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1981 • 336 citations

Improved techniques for homonuclear rotating-frame and isotropic mixing experiments

1987 • 335 citations

Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

1986 • 321 citations

Unified theory of exchange effects on nuclear magnetic resonance line shapes

1969 • 308 citations

Different conformations for the same polypeptide bound to chaperones DnaK and GroEL

1992 • 285 citations

Theory of the time dependent transferred nuclear Overhauser effect: Applications to structural analysis of ligand-protein complexes in solution

1983 • 285 citations

Direct Measurements of the Dissociation-Rate Constant for Inhibitor-Enzyme Complexes via the T1ρ and T2 (CPMG) Methods

1994 • 278 citations

High-resolution structure of an HIV zinc fingerlike domain via a new NMR-based distance geometry approach

1990 • 268 citations

Thrombin structure and function

1991 • 250 citations

Dynamic Nuclear Magnetic Resonance Spectroscopy

1975 • 220 citations

Distance geometry and related methods for protein structure determination from NMR data

1987 • 215 citations

Negative nuclear Overhuaser effects as probes of macromolecular structure

1972 • 209 citations

NMR structure of a receptor-bound G-protein peptide

1993 • 202 citations

Pulse methods for the simplification of protein NMR spectra

1975 • 191 citations

Interaction of the RNA-binding domain of the hnRNP C proteins with RNA.

1992 • 186 citations

Dipolar contribution to NMR spin-lattice relaxation of protons

1974 • 184 citations

Relaxation matrix analysis of 2D NMR data

1990 • 181 citations

Computational challenges for macromolecular structure determination by X-ray crystallography and solution NMRspectroscopy

1993 • 176 citations

The chaperonin GroEL binds a polypeptide in an .alpha.-helical conformation

1991 • 168 citations

An improved method for the determination of cross-relaxation rates from NOE data

1986 • 162 citations

Relaxation matrix refinement of the solution structure of squash trypsin inhibitor

1991 • 160 citations

Accounting for spin diffusion in the analysis of 2D NOE data

1986 • 149 citations

Disulfide bond isomerization in BPTI and BPTI(G36S): An NMR study of correlated mobility in proteins

1993 • 147 citations

Solution structure of the POU-specific DNA-binding domain of Oct-1

1993 • 144 citations

Transient proton-proton Overhauser effects in horse ferrocytochrome c

1978 • 143 citations

Multi-conformational peptide dynamics derived from NMR data: A new search algorithm and its application to antamanide

1991 • 136 citations

The Two-Dimensional Transferred Nuclear Overhauser Effect: Theory and Practice

1993 • 134 citations

Separation of chemical exchange and cross-relaxation effects in two-dimensional NMR spectroscopy

1985 • 133 citations

Mapping of the binding interfaces of the proteins of the bacterial phosphotransferase system, HPr and IIAglc

1993 • 126 citations

Multisite kinetics by quantitative two-dimensional NMR

1984 • 126 citations

The effects of proteins on the proton N.M.R. transverse relaxation times of water

1989 • 122 citations

Determining stereo-specific 1H nuclear magnetic resonance assignments from distance geometry calculations

1988 • 117 citations

Location and orientation relative to the micelle surface for glucagon in mixed micelles with dodecylphosphocholine EPR and NMR studies

1981 • 117 citations

Localization of tyrosine at the binding site of neurophysin II by negative nuclear Overhouser effects

1972 • 116 citations

The use of transferred nuclear Overhauser effects in the study of the conformations of small molecules bound to proteins

1979 • 113 citations

Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide

1992 • 113 citations

Calculation of the nuclear overhauser effect and the determination of proton-proton distances in the presence of internal motions

1990 • 112 citations

Selective and nonselective proton spin-lattice relaxation studies of enzyme-substrate interactions

1982 • 109 citations

Nuclear Magnetic Resonance in Biochemistry: Applications to Enzyme Systems

1973 • 107 citations

The effects of intermediate exchange processes on the estimation of equilibrium constants by NMR

1979 • 99 citations

Nuclear magnetic resonance studies of the interaction of peptides and hormones with bovine neurophysin

1973 • 98 citations

Nuclear Magnetic Resonance in Biochemistry: Applications to Enzyme Systems

1974 • 97 citations

Baseline distortion in real-fourier-transform NMR spectra

1988 • 95 citations

Fast and precise automatic baseline correction of one- and two-dimensional nmr spectra

1991 • 93 citations

A T1 rho-filtered two-dimensional transferred NOE spectrum for studying antibody interactions with peptide antigens

1993 • 91 citations

Nuclear magnetic resonance studies of the binding of trimethoprim to dihydrofolate reductase

1979 • 90 citations

Theoretical evaluation of the two-dimensional transferred nuclear overhauser effect

1991 • 90 citations

Assessment of errors involved in the determination of interproton distance ratios and distances by means of one- and two-dimensional NOE measurements

1985 • 88 citations

Stereochemistry of binding of the tetrapeptide acetyl-Pro-Ala-Pro-Tyr-NH2 to porcine pancreatic elastase

1986 • 85 citations

[3] Solvent suppression

1989 • 84 citations

[9] Distance geometry

1989 • 84 citations

Conformation of acetylcholine bound to the nicotinic acetylcholine receptor.

1988 • 83 citations

Characterization of biomolecular structure and dynamics by NMR cross relaxation

1994 • 82 citations

Relaxation-matrix analysis of the transferred nuclear overhauser effect for finite exchange rates

1992 • 82 citations

Baseline correction of 2D FT NMR spectra using a simple linear prediction extrapolation of the time-domain data

1989 • 81 citations

Quenching spin diffusion in selective measurements of transient overhauser effects in nuclear magnetic resonance. Applications to oligonucleotides

1994 • 81 citations

Thrombin-bound conformation of the C-terminal fragments of hirudin determined by transferred nuclear Overhauser effects

1990 • 79 citations

“False” transverse NOE enhancements in CAMELSPIN spectra

1986 • 79 citations

High-resolution NMR studies of fibrinogen-like peptides in solution: structure of a thrombin-bound peptide corresponding to residues 7-16 of the A.alpha. chain of human fibrinogen

1989 • 79 citations

Interaction of troponin I and troponin C

1991 • 78 citations

Nuclear Magnetic Resonance Studies of Solutions of the Rare-Earth Ions and Their Complexes. IV. Concentration and Temperature Dependence of the Oxygen-17 Transverse Relaxation in Aqueous Solutions

1969 • 75 citations

Fluorine-19 NMR spin-spin relaxation (T2) method for characterizing volatile anesthetic binding to proteins. Analysis of isoflurane binding to serum albumin

1992 • 75 citations

Restrained Molecular Dynamics Procedure for Protein Tertiary Structure Determination from NMR Data: A Lac Repressor Headpiece Structure Based on Information on J‐coupling and from Presence and Absence of NOE's

1986 • 74 citations

Conformation of methyl .beta.-lactoside bound to the ricin B-chain: interpretation of transferred nuclear Overhauser effects facilitated by spin simulation and selective deuteration

1990 • 74 citations

High-resolution NMR studies of fibrinogen-like peptides in solution: interaction of thrombin with residues 1-23 of the A.alpha. chain of human fibrinogen

1989 • 73 citations

G protein-bound conformation of mastoparan-X, a receptor-mimetic peptide.

1992 • 73 citations

NMR docking of a substrate into the X‐ray structure of staphylococcal nuclease

1992 • 73 citations

Chemical exchange and nmr T2 relaxation—The multisite case

1978 • 70 citations

Experimental NMR techniques for studies of protein-ligand interactions

1993 • 68 citations

Direct identification of relayed nuclear overhauser effects

1986 • 66 citations

Membrane-bound conformation of a signal peptide: A transferred nuclear Overhauser effect analysis

1993 • 65 citations

Dynamical NOE in multiple-spin systems undergoing chemical exchange

1989 • 65 citations

Dependence of NMR lineshape analysis upon chemical rates and mechanisms: Implications for enzyme histidine titrations

1980 • 64 citations

Protein dynamics and distance determination by NOE measurements

1988 • 63 citations

Solution conformation of peptides by the intramolecular nuclear Overhauser effect experiment. Study of valinomycin-K+

1978 • 63 citations

Elimination of multiple-step spin diffusion effects in two-dimensional NOE spectroscopy of nucleic acids

1988 • 63 citations

Nuclear magnetic resonance studies of bovine carbonic anhydrase. Binding of sulfonamides to the zinc enzyme

1971 • 61 citations

Induced peptide conformations in different antibody complexes: molecular modeling of the three-dimensional structure of peptide-antibody complexes using NMR-derived distance restraints

1992 • 61 citations

Binding of adenosine 5'-diphosphate to creatine kinase. An investigation using intermolecular nuclear Overhauser effect measurements

1976 • 58 citations

Averaging of cross-relaxation rates and distances for methyl, methylene, and aromatic ring protons due to motion or overlap. Extraction of accurate distances iteratively via relaxation matrix analysis of 2D NOE spectra

1992 • 57 citations

Restrained energy refinement with two different algorithms and force fields of the structure of the α-amylase inhibitor tendamistat determined by nmr in solution

1990 • 55 citations

Significant conformational changes in an antigenic carbohydrate epitope upon binding to a monoclonal antibody

1990 • 54 citations

Interactions of antibody aromatic residues with a peptide of cholera toxin observed by two-dimensional transferred nuclear Overhauser effect difference spectroscopy

1989 • 53 citations

Probing antibody diversity by 2D NMR: comparison of amino acid sequences, predicted structures, and observed antibody-antigen interactions in complexes of two antipeptide antibodies

1989 • 53 citations

Proton NMR investigation of the influence of interacting sites on the dynamics and thermodynamics of substrate and ligand binding to horseradish peroxidase

1992 • 52 citations

[14] Nuclear magnetic resonance line-shape analysis and determination of exchange rates

1989 • 52 citations

Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformations in creatine kinase complexes: Effects due to weak nonspecific binding

1993 • 52 citations

High-resolution NMR studies of fibrinogen-like peptides in solution: structural basis for the bleeding disorder caused by a single mutation of Gly(12) to Val(12) in the A.alpha. chain of human fibrinogen Rouen

1989 • 51 citations

Conformation of .beta.-methylmelibiose bound to the ricin B-chain as determined from transferred nuclear Overhauser effects

1992 • 50 citations

Variable-Target-Function and Build-up Procedures for the Calculation of Protein Conformation. Application to Bovine Pancreatic Trypsin Inhibitor Using Limited Simulated Nuclear Magnetic Resonance Data

1988 • 50 citations

Polypeptide hydration in mixed solvents at low temperatures

1992 • 49 citations

Nuclear magnetic resonance studies of the interaction of tryptophan with .alpha.-chymotrypsin

1968 • 48 citations

Solution structure of a platelet receptor peptide bound to bovine .alpha.-thrombin

1992 • 47 citations

The NMR determination of the IIAmtl binding site on HPr of the Escherichia coli phosphoenol pyruvate‐dependent phosphotransferase system

1993 • 47 citations

Antibodies against a peptide of cholera toxin differing in cross-reactivity with the toxin differ in their specific interactions with the peptide as observed by proton NMR spectroscopy

1990 • 47 citations

Nuclear Magnetic Resonance Studies of the Dynamic Aspects of Molecular Structure and Interaction in Biological Systems

1972 • 46 citations

Refined structure in solution of the sea anemone neurotoxin ShI.

1993 • 46 citations

NMR study of the complexes between a synthetic peptide derived from the B subunit of cholera toxin and three monoclonal antibodies against it

1988 • 45 citations

Relay artifacts in ROESY spectra

1987 • 44 citations

Internal motional averaging and three-dimensional structure determination by nuclear magnetic resonance

1992 • 44 citations

Influence of conformational exchange on the 2D NOESY spectra of biomolecules existing in multiple conformations

1992 • 43 citations

NMR-derived model for a peptide-antibody complex

1990 • 42 citations

Accounting for Ligand-Protein Interactions in the Relaxation-Matrix Analysis of Transferred Nuclear Overhauser Effects

1994 • 41 citations

Measurement of proton relaxation rates in proteins

1993 • 40 citations

Use of transferred nuclear Overhauser effect measurements to compare binding of coenzyme analogs to dihydrofolate reductase

1983 • 39 citations

Measurement of relaxation rates in crowded NMR spectra by selective coherence transfer

1992 • 36 citations

Structure refinement of a cyclic peptide from two-dimensional NMR data and molecular modeling

1987 • 36 citations

Conformation of an enzyme-bound substrate of staphylococcal nuclease as determined by NMR

1991 • 35 citations

Complete relaxation matrix analysis of transferred nuclear overhauser effects

1992 • 35 citations

Intermolecular spin diffusion as a method for studying macromolecule-ligand interactions

1979 • 35 citations

Conformational and dynamic changes of D- and L-tryptophan due to stereoselective interaction with human serum albumin, as revealed by proton-selective relaxation rate measurements

1991 • 34 citations

[15] Applicability of magnetization transfer nuclear magnetic resonance to study chemical exchange reactions

1989 • 33 citations

Protein Indirect Relaxation Effects in Exchange-Transferred NOESY by a Rate-Matrix Analysis

1993 • 31 citations

[17] Ligand conformations and ligand-enzyme interactions as studied by the nuclear overhauser effect

1989 • 31 citations

Small molecule conformation in the receptor‐bound state by the two‐dimensional spin exchange experiment

1987 • 31 citations

Influence of molecular geometry on uncertainty in distances determined from NOE

1989 • 31 citations

Conformational stability of a thrombin-binding peptide derived from the hirudin C-terminus

1992 • 30 citations

Theory and experimental results of transfer NOE experiments. II. The influence of residual mobility and relaxation centers inside the protein on the size of transfer NOEs

1992 • 30 citations

Nuclear‐magnetic‐resonance studies on the conformation of membrane‐bound α‐mating factor

1986 • 30 citations

Interaction of phospholipase A2 with thioether amide containing phospholipid analogs

1993 • 30 citations

Determination of the conformations of bound peptides using NMR-transferred nOe techniques

1993 • 29 citations

Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C

1992 • 29 citations

Direct measurement of agonist binding to genetically engineered peptides of the acetylcholine receptor by selective T1 NMR relaxation

1990 • 29 citations

Transfer nuclear Overhauser effect study of the conformation of oxytocin bound to bovine neurophysin I

1993 • 28 citations

Nuclear magnetic resonance studies of the interaction of trans-cinnamate with .alpha.-chymotrypsin

1970 • 28 citations

NMR study of the solution conformation of rat atrial natriuretic factor (7-23) in sodium dodecyl sulfate micelles

1988 • 28 citations

Extracting accurate distances and bounds from 2D NOE exchangeable proton peaks

1993 • 27 citations

Complete elimination of spin diffusion from selected resonances in two-dimensional cross-relaxation spectra of macromolecules by a novel pulse sequence (SNOESY)

1992 • 27 citations

High-resolution NMR studies of fibrinogen-like peptides in solution: resonance assignments and conformational analysis of residues 1-23 of the A.alpha. chain of human fibrinogen

1988 • 27 citations

NMR Studies of Ligand–Macromolecule Interactions

1990 • 27 citations

Measurement of cross relaxation between two selected nuclei by synchronous nutation of magnetization in nuclear magnetic resonance

1993 • 26 citations

Thrombin exosite for fibrinogen recognition is partially accessible in prothrombin

1993 • 25 citations

Refinement of the NMR solution structure of a protein to remove distortions arising from neglect of internal motion

1991 • 25 citations

[18] Interpreting protein dynamics with nuclear magnetic resonance relaxation measurements

1989 • 24 citations

Measuring relative acetylcholine receptor agonist binding by selective proton nuclear magnetic resonance relaxation experiments

1988 • 23 citations

Structural and kinetic studies of the Fab fragment of a monoclonal anti-spin label antibody by nuclear magnetic resonance

1991 • 23 citations

Conformation of NADP+ bound to a type II dihydrofolate reductase

1991 • 23 citations

A general multistate model for the analysis of hydrogen‐exchange kinetics

1980 • 23 citations

Chemical-Shift and Linewidth Characteristics of Reversibly Bound Ligands

1993 • 23 citations

Maximum-Likelihood-Constrained Deconvolution of Two-Dimensional NMR Spectra. Accuracy of Spectral Quantification

1993 • 21 citations

Measurement of Overhauser effects in magnetic resonance of proteins by synchronous nutation

1992 • 21 citations

1H NMR Evaluation of Yeast Isoenzyme-1 Ferricytochrome c Equilibrium Exchange Dynamics in Noncovalent Complexes with Two Forms of Yeast Cytochrome c Peroxidase

1994 • 20 citations

Scaling NOESY cross peaks involving methyl protons

1990 • 20 citations

Comparison of the membrane-bound states of two structurally similar .vdelta.-selective opioid peptides by transferred nuclear Overhauser effect spectroscopy and molecular modeling

1993 • 19 citations

Nuclear magnetic resonance studies of flexible opiate conformations at monoclonal antibody binding sites

1989 • 19 citations

NMR analyses of the conformations of L-isoleucine and L-valine bound to Escherichia coli isoleucyl-tRNA synthetase

1987 • 19 citations

Effect of slow conformational exchange on 2D NOTEY spectra

1991 • 18 citations

Improved Measurement of Longer Proton-Proton Distances in Proteins by Relaxation Network Editing

1993 • 18 citations

Direct cross-relaxation NOESY (D.NOESY). A method for removing spin-diffusion cross peaks from two-dimensional NOE spectra of macromolecules

1991 • 17 citations

Selective inversion-recovery ΔNOE spectroscopy with truncated relaxation delays. I. Techniques for minimizing spin diffusion in studies of protein-bound conformations of small molecules

1985 • 17 citations

Proton magnetic resonance studies of cholinergic ligand binding to the acetylcholine receptor in its membrane environment.

1979 • 17 citations

[10] Nuclear magnetic resonance for studying peptide — Antibody complexes by transferred nuclear overhauser effect difference spectroscopy

1991 • 17 citations

Refinement of the thrombin‐bound structure of a hirudin peptide by a restrained electrostatically driven Monte Carlo method

1992 • 16 citations

NMR Analysis Reveals a Positively Charged Hydrophobic Domain as a Common Motif to Bound Acetylcholine and d-Tubocurarine

1994 • 16 citations

Nuclear Overhauser effect studies on the conformations of Mg(alpha, beta-methylene)ATP bound to Escherichia coli methionyl-tRNA synthetase

1991 • 15 citations

Investigation of an octapeptide inhibitor of Escherichia coli ribonucleotide reductase by transferred nuclear Overhauser effect spectroscopy

1991 • 15 citations

Spin-Lattice Relaxation Studies by Selective Hartmann-Hahn Transfer

1993 • 14 citations

Conformation of MgATP bound to nucleotidyl and phosphoryl transfer enzymes 1H‐transferred NOE measurements on complexes of methionyl tRNA synthetase and pyruvate kinase

1992 • 14 citations

Improved methods for solvent suppression and baseline correction in two-dimensional transferred NOE experiments

1992 • 14 citations

Thrombin hydrolysis of an N-terminal peptide from fibrinogen Lille: kinetic and NMR studies

1992 • 14 citations

Amide Proton Spin-Lattice Relaxation in Polypeptides

1978 • 13 citations

Binding features of diacetylmorphine (heroin) in whole blood and in blood fractions

1985 • 12 citations

Proton and tritium nmr relaxation studies of peptide inhibitor binding to bacterial collagenase: Conformation and dynamics

1991 • 12 citations

Conformational studies of cyclic peptide structures in solution from 1H‐Nmr data by distance geometry calculation and restrained energy minimization

1990 • 11 citations

Recognition of DNA by GAL4 in Solution: Use of a Monomeric Protein-DNA Complex for Study by NMR

1994 • 11 citations

Two‐dimensional NMR investigations of the interactions of antibodies with peptide antigens

1993 • 11 citations

Effects of internal motions on the development of the two-dimensional transferred nuclear Overhauser effect

1991 • 11 citations

Thrombin‐bound conformation of a cyclic anticoagulant peptide using transferred nuclear Overhauser effect (NOE), distance geometry, and NOE simulations

1994 • 11 citations

The solution conformations of ferrichrome and deferriferrichrome determined by 1H‐nmr spectroscopy and computational modeling

1990 • 10 citations

Conformation of ATP and ADP Bound to N10-Formyltetrahydrofolate Synthetase Determined by TRNOE NMR Spectroscopy

1994 • 10 citations

[10] Selective relaxation techniques

1989 • 10 citations

Conformation of 6,7-dimethyl-8-ribityllumazine bound to β-subunits of heavy riboflavin synthase: Transferred nuclear overhauser effect (TrNOE) studies employing ω1-13C-filtered NOESY including a novel technique for zero quantum suppression

1992 • 9 citations

The contributions to amide proton spin-lattice relaxation in a small peptide

1978 • 7 citations

Structure and dynamics of α-chymotrypsin-N-trifluoroacetyl-4-fluorophenylalanine complexes

1991 • 6 citations

Optimized acquisition and processing of homonuclear 3D NMR spectra. Applications to transferred-NOE experiments

1992 • 5 citations

Geometrical Error in Biomolecular Structures Determined from NOESY Data Using a Relaxation Rate Matrix Analysis

1993 • 5 citations

A heteronuclear 3D NMR experiment which allows detection of all NOEs for a molecule while providing 15N frequency separation of degenerate amide protons

1992 • 4 citations

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