Induced peptide conformations in different antibody complexes: molecular modeling of the three-dimensional structure of peptide-antibody complexes using NMR-derived distance restraints

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Multiple quantum filters for elucidating NMR coupling networks

1982 • 1,780 citations

Elucidation of cross relaxation in liquids by two-dimensional N.M.R. spectroscopy

1980 • 1,490 citations

Canonical structures for the hypervariable regions of immunoglobulins

1987 • 1,357 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

Conformations of immunoglobulin hypervariable regions

1989 • 1,165 citations

Exchangeable proton NMR without base-line distorsion, using new strong-pulse sequences

1982 • 1,052 citations

Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance

1983 • 1,012 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Three-dimensional structure of an antibody-antigen complex.

1987 • 615 citations

Continuous and discontinuous protein antigenic determinants

1986 • 582 citations

Phosphocholine binding immunoglobulin Fab McPC603

1986 • 576 citations

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase

1987 • 556 citations

Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli

1991 • 556 citations

Intrinsic and Extrinsic Factors in Protein Antigenic Structure

1985 • 481 citations

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.

1989 • 456 citations

Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 Å and 1.9 Å resolution

1980 • 455 citations

Molecular dynamics of native protein

1983 • 358 citations

Crystal Structures of an Antibody to a Peptide and Its Complex with Peptide Antigen at 2.8 Å

1990 • 352 citations

Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.

1978 • 293 citations

Molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-Å resolution

1975 • 266 citations

Molecular dynamics of native protein

1983 • 190 citations

The galactan‐binding immunoglobulin Fab J539: An x‐ray diffraction study at 2.6‐Å resolution

1986 • 175 citations

The Physical Basis for Induction of Protein-Reactive Antipeptide Antibodies

1988 • 130 citations

Structure of a novel bence-jones protein (Rhe) fragment at 1·6 Å resolution

1983 • 117 citations

Synthetic peptides: a next generation of vaccines?

1987 • 100 citations

Antibodies against synthetic peptides of the B subunit of cholera toxin: crossreaction and neutralization of the toxin.

1983 • 98 citations

Theoretical evaluation of the two-dimensional transferred nuclear overhauser effect

1991 • 90 citations

Structure of an antibody combining site by magnetic resonance

1977 • 89 citations

Stereochemistry of binding of the tetrapeptide acetyl-Pro-Ala-Pro-Tyr-NH2 to porcine pancreatic elastase

1986 • 85 citations

Binding to native proteins by antipeptide monoclonal antibodies.

1991 • 75 citations

Magnetic resonance of a monoclonal anti-spin-label antibody

1984 • 62 citations

Interactions of antibody aromatic residues with a peptide of cholera toxin observed by two-dimensional transferred nuclear Overhauser effect difference spectroscopy

1989 • 53 citations

Probing antibody diversity by 2D NMR: comparison of amino acid sequences, predicted structures, and observed antibody-antigen interactions in complexes of two antipeptide antibodies

1989 • 53 citations

Antibodies against a peptide of cholera toxin differing in cross-reactivity with the toxin differ in their specific interactions with the peptide as observed by proton NMR spectroscopy

1990 • 47 citations

NMR study of the complexes between a synthetic peptide derived from the B subunit of cholera toxin and three monoclonal antibodies against it

1988 • 45 citations

NMR-derived model for a peptide-antibody complex

1990 • 42 citations

Synthetic peptides as the basis for future vaccines

1986 • 39 citations

Contribution of tryptophan residues to the combining site of a monoclonal anti-dinitrophenyl spin-label antibody

1987 • 38 citations

Both cholera toxin-induced adenylate cyclase activation and cholera toxin biological activity are inhibited by antibodies against related synthetic peptides.

1984 • 35 citations

Three distinct epitopes within the loop region of hen egg lysozyme defined with monoclonal antibodies.

1985 • 34 citations

Monoclonal BALB/c anti‐progesterone antibodies use family IX variable region heavy chain genes

1987 • 33 citations

Interaction of monoclonal anti-peptide antibodies with lysozyme.

1985 • 25 citations

Structural and kinetic studies of the Fab fragment of a monoclonal anti-spin label antibody by nuclear magnetic resonance

1991 • 23 citations

Crystallization and preliminary crystallographic data for an antiprogesterone monoclonal antibody Fab′ and steroid-Fab′ complexes

1987 • 16 citations