Selectin ligands, leukocyte trafficking, and fucosyltransferase genes

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

1993 • 1,427 citations

ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le ^x

1990 • 1,315 citations

Two distinct classes of carbohydrate-recognition domains in animal lectins.

1988 • 1,259 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

1990 • 997 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

Recognition by Elam-1 of the Sialyl-Le ^x Determinant on Myeloid and Tumor Cells

1990 • 976 citations

Selectin ligands.

1994 • 943 citations

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation.

1985 • 886 citations

PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes

1989 • 878 citations

ELAM-1 is an adhesion molecule for skin-homing T cells

1991 • 843 citations

Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

1989 • 799 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

1996 • 723 citations

ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA

1990 • 712 citations

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

1992 • 698 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

Leukocyte Trafficking Mediated by Selectin-Carbohydrate Interactions

1995 • 648 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140

1991 • 592 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells

1989 • 538 citations

Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins

1996 • 534 citations

Cloning of a lymphocyte homing receptor reveals a lectin domain

1989 • 522 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1991 • 505 citations

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding

1995 • 435 citations

Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains

1989 • 428 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein.

1986 • 402 citations

Characterization of E-selectin-deficient mice: Demonstration of overlapping function of the endothelial selectins

1994 • 384 citations

Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.

1992 • 383 citations

PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus

1995 • 383 citations

A central role for microvillous receptor presentation in leukocyte adhesion under flow

1995 • 380 citations

Activation-independent binding of human memory T cells to adhesion molecule ELAM-1

1991 • 379 citations

Induction and detection of a human endothelial activation antigen in vivo.

1986 • 378 citations

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

1995 • 358 citations

Post-translational Modifications of Recombinant P-selectin Glycoprotein Ligand-1 Required for Binding to P- and E-selectin

1996 • 340 citations

ELFT: A gene that directs the expression of an ELAM-1 ligand

1990 • 338 citations

Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin

1993 • 330 citations

Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes.

1994 • 329 citations

Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant

1994 • 311 citations

Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.

1989 • 308 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues.

1991 • 295 citations

Tyrosine Sulfation of P-selectin Glycoprotein Ligand-1 Is Required for High Affinity Binding to P-selectin

1995 • 290 citations

P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli.

1995 • 287 citations

Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.

1991 • 281 citations

Neutrophils roll on adherent neutrophils bound to cytokine-induced endothelial cells via L-selectin on the rolling cells.

1994 • 279 citations

The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine.

1994 • 273 citations

Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody.

1994 • 267 citations

Structures of the O-Glycans on P-selectin Glycoprotein Ligand-1 from HL-60 Cells

1996 • 260 citations

Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140

1990 • 257 citations

Leu-8/TQ1 is the human equivalent of the Mel-14 lymph node homing receptor

1989 • 256 citations

Structure of sialylated fucosyl lactosaminoglycan isolated from human granulocytes.

1984 • 238 citations

Involvement of Sialic Acid on Endothelial Cells in Organ-Specific Lymphocyte Recirculation

1985 • 236 citations

Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain.

1984 • 233 citations

Human eosinophil adherence to vascular endothelium mediated by binding to vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule 1.

1991 • 233 citations

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation.

1983 • 232 citations

Hematopoietic defects in mice lacking the sialomucin CD34

1996 • 229 citations

Endothelial leucocyte adhesion molecule-1 (ELAM-1) expression in cutaneous inflammation

1991 • 212 citations

Identification of a glycoprotein ligand for E-selectin on mouse myeloid cells.

1993 • 201 citations

The P-selectin Glycoprotein Ligand Functions as a Common Human Leukocyte Ligand for P- and E-selectins

1995 • 195 citations

Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules.

1984 • 194 citations

6'-Sulfated Sialyl Lewis x Is a Major Capping Group of GlyCAM-1

1994 • 191 citations

Isolation and characterization of polyfucosylated lactosaminoglycan from human granulocytes.

1984 • 188 citations

Comparison of L-selectin and E-selectin ligand specificities: The L-selectin can bind the E-selectin ligands Sialyl Lex and Sialyl Lea

1992 • 179 citations

Monospecific and common glycoprotein ligands for E- and P-selectin on myeloid cells.

1994 • 179 citations

The fucosyltransferase FucT-VII regulates E-selectin ligand synthesis in human T cells.

1996 • 178 citations

The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.

1991 • 175 citations

High affinity binding of the leucocyte adhesion molecule L-selectin to 3′-sulphated-Lea and -Lex oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides

1992 • 173 citations

Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-α) in allergic contact dermatitis (rhus dermatitis)

1991 • 166 citations

Identification of the Sulfated Monosaccharides of GlyCAM-1, an Endothelial-Derived Ligand for L-Selectin

1994 • 166 citations

P-selectin Glycoprotein Ligand-1 Is the Major Counter-receptor for P-selectin on Stimulated T Cells and Is Widely Distributed in Non-functional Form on Many Lymphocytic Cells

1995 • 163 citations

A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.

1990 • 162 citations

Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules.

1995 • 161 citations

Cloning of a human alpha(1,3)-fucosyltransferase gene that encodes ELFT but does not confer ELAM-1 recognition on Chinese hamster ovary cell transfectants.

1991 • 160 citations

Expression of the α(1,3)Fucosyltransferase Fuc-TVII in Lymphoid Aggregate High Endothelial Venules Correlates with Expression of L-Selectin Ligands

1996 • 146 citations

Expression and functional characterization of a soluble form of endothelial-leukocyte adhesion molecule 1.

1991 • 141 citations

Induced expression of endothelial-leukocyte adhesion molecules in human cardiac allografts.

1991 • 124 citations

Blood cell dynamics in P-selectin-deficient mice

1995 • 119 citations

Heat-stable antigen (CD24) as ligand for mouse P-selectin

1994 • 115 citations

Monosialogangliosides of Human Myelogenous Leukemia HL60 Cells and Normal Human Leukocytes. 2. Characterization of E-Selectin Binding Fractions, and Structural Requirements for Physiological Binding to E-Selectin

1996 • 112 citations

Molecular Cloning, Expression, Chromosomal Assignment, and Tissue-specific Expression of a Murine α-(1,3)-Fucosyltransferase Locus Corresponding to the Human ELAM-1 Ligand Fucosyl Transferase

1995 • 108 citations

An in vitro model of lymphocyte homing. I. Characterization of the interaction between thoracic duct lymphocytes and specialized high-endothelial venules of lymph nodes.

1977 • 107 citations

Characterization of a human homologue of the murine peripheral lymph node homing receptor.

1989 • 102 citations

Leukocyte rolling in venules of striated muscle and skin is mediated by P-selectin, not by L-selectin

1994 • 100 citations

INDUCED EXPRESSION OF ENDOTHELIAL-LEUKOCYTE ADHESION MOLECULES IN HUMAN CARDIAC ALLOGRAFTS

1991 • 100 citations

Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.

1989 • 99 citations

Cell surface lectins in the immune system

1993 • 97 citations

Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules.

1989 • 95 citations

Blood cell dynamics in P-selectin-deficient mice

1995 • 93 citations

Structures of sialylated fucosyl polylactosaminoglycans isolated from chronic myelogenous leukemia cells.

1985 • 92 citations

Monosialogangliosides of Human Myelogenous Leukemia HL60 Cells and Normal Human Leukocytes. 1. Separation of E-Selectin Binding from Nonbinding Gangliosides, and Absence of Sialosyl-Le^x Having Tetraosyl to Octaosyl Core

1996 • 88 citations

The Mel 14 antibody binds to the lectin domain of the murine peripheral lymph node homing receptor.

1990 • 80 citations

Further characterization of the interaction between L-selectin and its endothelial ligands

1992 • 76 citations

Enzymatic synthesis of a 6′-sulphated sialyl-Lewis^x which is an inhibitor of L-selectin binding to peripheral addressin

1994 • 70 citations

Enzymes involved in mammalian oligosaccharide biosynthesis

1994 • 67 citations

Selective expression of sialyl-Lewis x and Lewis a epitopes, putative ligands for L-selectin, on peripheral lymph-node high endothelial venules.

1992 • 66 citations

The complement binding-like domains of the murine homing receptor facilitate lectin activity.

1991 • 64 citations

Differential expression of an E-selectin ligand (SLex) by two Chinese hamster ovary cell lines transfected with the same alpha (1,3)-fucosyltransferase gene (ELFT).

1994 • 63 citations

An in vitro Model of Lymphocyte Homing

1977 • 63 citations

A role for ELAM-1 in the pathogenesis of MOF during septic shock

1992 • 61 citations

Localization of ligands for L-selectin in mouse peripheral lymph node high endothelial cells by colloidal gold conjugates

1994 • 58 citations

Biosynthesis of GlyCAM-1, a Mucin-like Ligand for L-Selectin

1995 • 51 citations

Structure of a novel sialylated fucosyl lacto-N-norhexaosylceramide isolated from chronic myelogenous leukemia cells.

1986 • 50 citations

Infiltration of Both T Cells and Neutrophils in the Skin Is Accompanied by the Expression of Endothelial Leukocyte Adhesion Molecule-1 (ELAM-1): An Immunohistochemical and Ultrastructural Study

1992 • 46 citations

Total Synthesis of 3'-O-Sialyl, 6'-O-Sulfo Lewisx, NeuAc.alpha.2.fwdarw.3(6-O-SO3Na)Ga1.beta.1.fwdarw.4(Fuc.alpha.1.fwdarw.3)GlcNAc.beta.-OMe: A Major Capping Group of GLYCAM-I

1994 • 33 citations

Assignment of the GLG1 Gene for MG-160, a Fibroblast Growth Factor and E-Selectin Binding Membrane Sialoglycoprotein of the Golgi Apparatus, to Chromosome 16q22-q23 by Fluorescence in Situ Hybridization

1995 • 24 citations

Administration of tumor necrosis factor α (TNFα) inhibitors after exposure to TNFα prevents development of the maximal biological effect: An argument for clinical treatment with TNFα inhibitors

1992 • 19 citations