Hematopoietic defects in mice lacking the sialomucin CD34

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo*

1970 • 1,031 citations

Development of hematopoietic stem cell activity in the mouse embryo

1994 • 914 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Expression of the CD34 gene in vascular endothelial cells

1990 • 857 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.

1991 • 628 citations

Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture

1991 • 615 citations

Antigen CD34+ marrow cells engraft lethally irradiated baboons.

1988 • 608 citations

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures.

1990 • 574 citations

Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma

1991 • 538 citations

An early pre-liver intraembryonic source of CFU-S in the developing mouse

1993 • 525 citations

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1992 • 417 citations

CD34 expression by stromal precursors in normal human adult bone marrow

1991 • 289 citations

Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells

1994 • 274 citations

The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development

1995 • 240 citations

Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells

1994 • 210 citations

The CD34 Antigen: Structure, Biology, and Potential Clinical Applications

1992 • 198 citations

The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts

1991 • 188 citations

Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin

1994 • 185 citations

Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules.

1995 • 161 citations

Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells

1994 • 153 citations

Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues

1995 • 144 citations

Signaling and induction of enhanced cytoadhesiveness via the hematopoietic progenitor cell surface molecule CD34

1994 • 125 citations

CD34+ endothelial cell lines derived from murine yolk sac induce the proliferation and differentiation of yolk sac CD34+ hematopoietic progenitors

1995 • 92 citations

CD34-positive cells: biology and clinical relevance.

1995 • 87 citations

Two alternative forms of cDNA encoding CD34.

1993 • 62 citations

Up-regulation of surface CD34 is associated with protein kinase C-mediated hyperphosphorylation of CD34.

1992 • 62 citations

CD34 + positive haemopoietic cells:Biology and clinical applications

1994 • 61 citations

Expression of leukocyte antigen CD34 by brain capillaries in Alzheimer's disease and neurologically normal subjects

1992 • 48 citations

Molecular characterization of CD34+ human hematopoietic progenitor cells

1995 • 47 citations

Evidence for engraftment of donor-type multipotent CD34+ cells in a patient with selective T-lymphocyte reconstitution after bone marrow transplantation for B-SCID

1994 • 38 citations

Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma

1991 • 36 citations

Retention of progenitor cell function in CD34+ cells purified using a novel O-sialoglycoprotease.

1992 • 25 citations

CD34 expression by stromal precursors in normal human adult bone marrow

1991 • 23 citations

Certain anti‐CD34 monoclonal antibodies induce homotypic adhesion of leukemic cell lines in a CD18‐dependent and a CD18‐independent way

1994 • 21 citations

Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells

1994 • 16 citations

SLE^x expression of normal CD 34 positive bone marrow haemopoietic progenitor cells

1994 • 13 citations

Molecular characterization of CD34 + human hematopoietic progenitor cells

1995 • 8 citations

Evidence for engraftment of donor-type multipotent CD34+ cells in a patient with selective T-lymphocyte reconstitution after bone marrow transplantation for B-SCID

1994 • 3 citations

IDENTIFICATION OF A NOVEL, RARE, HUMAN BONE-MARROW POPULATION WITH HEMATOPOIETIC STEM-CELL ACTIVITY .1. CELL ISOLATION AND INVITRO STUDIES

1991 • 2 citations