Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology.

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells.

1984 • 944 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon.

1983 • 638 citations

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

1984 • 579 citations

Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.

1986 • 496 citations

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

1983 • 487 citations

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.

1987 • 418 citations

Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.

1986 • 401 citations

Induction and detection of a human endothelial activation antigen in vivo.

1986 • 378 citations

Cancer Immunotherapy Using Interleukin-2 and Interleukin-2-Activated Lymphocytes

1986 • 307 citations

Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome.

1986 • 275 citations

Immunoglobulin M antibodies present in the acute phase of Kawasaki syndrome lyse cultured vascular endothelial cells stimulated by gamma interferon.

1986 • 244 citations

Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome.

1988 • 225 citations

INDUCIBLE EXPRESSION OF CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS AND THE IMMUNOGENICITY OF VASCULAR ENDOTHELIUM

1986 • 211 citations

Reversal of lymphocyte activation in vivo in the Kawasaki syndrome by intravenous gammaglobulin.

1987 • 179 citations

Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts.

1987 • 171 citations

Lymphocyte recruitment in delayed-type hypersensitivity. The role of IFN-gamma.

1988 • 170 citations

LYTIC ANTI-ENDOTHELIAL CELL ANTIBODIES IN HAEMOLYTIC-URAEMIC SYNDROME

1988 • 169 citations

Expression of Ia-like antigens by human vascular endothelial cells is inducible in vitro: demonstration by monoclonal antibody binding and immunoprecipitation.

1982 • 147 citations

Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture.

1987 • 142 citations

Three distinct classes of regulatory cytokines control endothelial cell MHC antigen expression. Interactions with immune gamma interferon differentiate the effects of tumor necrosis factor and lymphotoxin from those of leukocyte alpha and fibroblast beta interferons.

1988 • 142 citations

THE HUMAN MIXED LYMPHOCYTE-ENDOTHELIUM CULTURE INTERACTION

1975 • 100 citations

Effects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells

2007 • 97 citations

The fine structure of the vascular response in hapten-specific delayed hypersensitivity and contact dermatitis.

1967 • 95 citations

Functional and morphological changes in post‐capillary venules in relation to lymphocytic infiltration into BCG‐induced granulomata in rat skin

1985 • 66 citations

Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones.

1985 • 52 citations

Effects of recombinant gamma-interferon on HLA-DR and DQ expression by skin cells in short-term organ culture.

1988 • 45 citations

Tumor necrosis factor and immune interferon act in concert to slow the lateral diffusion of proteins and lipids in human endothelial cell membranes.

1988 • 29 citations