The amino acid residues 1–128 in the α subunit of the nicotinic acetylcholine receptor contain assembly signals

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Injected anti-sense RNAs specifically block messenger RNA translation in vivo.

1985 • 410 citations

Ligand-gated ion channels in the brain: The amino acid receptor superfamily

1990 • 397 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

Functional Architecture of the Nicotinic Acetylcholine Receptor: From Electric Organ to Brain

1991 • 327 citations

Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways

1993 • 286 citations

Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor

1989 • 279 citations

Neurotransmitter action: Opening of ligand-gated ion channels

1993 • 267 citations

Nicotinic acetylcholine receptor and superfamily of ligand-gated ion channels

1990 • 260 citations

Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes

1981 • 197 citations

Assembly of the inhibitory glycine receptor: Identification of amino acid sequence motifs governing subunit stoichiometry

1993 • 183 citations

The N-terminal domains of acetylcholine receptor subunits contain recognition signals for the initial steps of receptor assembly

1992 • 149 citations

Acetylcholine receptor assembly: Subunit folding and oligomerization occur sequentially

1993 • 146 citations

Molecular Structure of the Nicotinic Acetylcholine Receptor

1983 • 138 citations

Mutational analysis of muscle nicotinic acetylcholine receptor subunit assembly.

1990 • 122 citations

Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum.

1987 • 119 citations

Assembly of the mammalian muscle acetylcholine receptor in transfected COS cells.

1991 • 116 citations

Assembly intermediates of the mouse muscle nicotinic acetylcholine receptor in stably transfected fibroblasts.

1990 • 102 citations

Mouse-Torpedo hybrid acetylcholine receptors: functional homology does not equal sequence homology.

1985 • 98 citations

Functional properties of nicotinic acetylcholine receptor subunits expressed in various combinations

1987 • 95 citations

Extracellular domains mediating ɛ subunit interactions of muscle acetylcholine receptor

1991 • 94 citations

Assembly and N-glycosylation of all ACh receptor subunits are required for their efficient insertion into plasma membranes

1989 • 79 citations

Identification of two amino acid residues in the ϵ subunit that promote mammalian muscle acetylcholine receptor assembly in COS cells

1991 • 75 citations

Efficiency of acetylcholine receptor subunit assembly and its regulation by cAMP.

1991 • 74 citations

Fibroblasts transfected with Torpedo acetylcholine receptor beta-, gamma-, and delta-subunit cDNAs express functional receptors when infected with a retroviral alpha recombinant.

1989 • 72 citations

Assembly of Torpedo acetylcholine receptors in Xenopus oocytes.

1991 • 71 citations

Site-directed mutagenesis of the conserved N-glycosylation site on the nicotinic acetylcholine receptor subunits

1991 • 67 citations

Assembly of mutant subunits of the nicotinic acetylcholine receptor lacking the conserved disulfide loop structure.

1992 • 65 citations

Acetylcholine receptor in a C2 muscle cell variant is retained in the endoplasmic reticulum.

1989 • 55 citations

Expression of Neurotransmitter Receptors and Voltage-Activated Channels from Brain mRNA in Xenopus Oocytes

1989 • 55 citations

Activation of skeletal muscle nicotinic acetylcholine receptors

1992 • 47 citations

Sequences on the N-terminus of ACh receptor subunits regulate their assembly

1992 • 33 citations