A new perspective: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies

miR-15 and miR-16 induce apoptosis by targeting BCL2

2005 • 3,424 citations

Unmutated Ig VH Genes Are Associated With a More Aggressive Form of Chronic Lymphocytic Leukemia

1999 • 2,674 citations

Ig V Gene Mutation Status and CD38 Expression As Novel Prognostic Indicators in Chronic Lymphocytic Leukemia

1999 • 2,557 citations

Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma

1991 • 1,874 citations

Chronic Lymphocytic Leukemia

2005 • 1,679 citations

A blast from the past: clearance of apoptotic cells regulates immune responses

2002 • 1,558 citations

Gene Expression Profiling of B Cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

2001 • 934 citations

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

1998 • 899 citations

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

2007 • 846 citations

Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL

2003 • 732 citations

Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

2000 • 669 citations

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

2005 • 579 citations

Evidence for an Association Between Chlamydia psittaci and Ocular Adnexal Lymphomas

2004 • 538 citations

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations

2006 • 507 citations

Vimentin is secreted by activated macrophages

2002 • 495 citations

The many faces of filamin: A versatile molecular scaffold for cell motility and signalling

2004 • 489 citations

Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition

1999 • 461 citations

Polyclonal Ig production after Epstein-Barr virus infection of human lymphocytes in vitro

1977 • 378 citations

Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

2002 • 375 citations

Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia

2007 • 368 citations

B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes

2002 • 358 citations

Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.

1996 • 354 citations

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

2005 • 331 citations

Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis

2007 • 328 citations

Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia

2004 • 280 citations

Thematic review series: The Immune System and Atherogenesis. The role of natural antibodies in atherogenesis

2005 • 251 citations

Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to production of natural autoantibodies

1990 • 222 citations

Characterization of Overt B-Cell Lymphomas in Patients With Hepatitis C Virus Infection

1997 • 220 citations

Direct Interactions between Subunits of CPSF and the U2 snRNP Contribute to the Coupling of Pre-mRNA 3′ End Processing and Splicing

2006 • 191 citations

Chronic lymphocytic leukemic (CLL) cells secrete multispecific autoantibodies

1988 • 179 citations

Vimentin Expressed onMycobacterium tuberculosis-Infected Human Monocytes Is Involved in Binding to the NKp46 Receptor

2006 • 174 citations

A protective role for innate immunity in systemic lupus erythematosus

2004 • 171 citations

CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells

2007 • 161 citations

Cell surface expression of intermediate filament proteins vimentin and lamin B1 in human neutrophil spontaneous apoptosis

2005 • 160 citations

Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton

2003 • 152 citations

Dual mode of action of Bac7, a proline-rich antibacterial peptide

2006 • 127 citations

Evidence for somatic selection of natural autoantibodies.

1992 • 126 citations

Structure-function studies on a polyreactive (natural) autoantibody. Polyreactivity is dependent on somatically generated sequences in the third complementarity-determining region of the antibody heavy chain.

1994 • 120 citations

Group A Streptococcal Myonecrosis: Increased Vimentin Expression after Skeletal‐Muscle Injury Mediates the Binding ofStreptococcus pyogenes

2006 • 110 citations

Autoantibodies to citrullinated proteins in rheumatoid arthritis: clinical performance and biochemical aspects of an RA-specific marker

2004 • 109 citations

Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2

2003 • 108 citations

Respiratory tract infections and subsequent risk of chronic lymphocytic leukemia

2006 • 104 citations

The role of IgM antibodies in the recognition and clearance of apoptotic cells

2005 • 103 citations

"De Novo" Sequencing of Peptides Recovered from In-Gel Digested Proteins by Nanoelectrospray Tandem Mass Spectrometry

2002 • 94 citations

Entry of the bacterial pathogen Listeria monocytogenes into mammalian cells

2007 • 94 citations

Epstein-Barr virus (EBV) can immortalize B-cll cells activated by cytokines.

1994 • 67 citations

Mechanism of autoimmune hemolytic anemia in chronic lymphocytic leukemia

1993 • 59 citations

Activated cofilin colocalises with Arp2/3 complex in apoptotic blebs during programmed cell death

2005 • 42 citations

Identification of poly-reactive natural IgM antibody that recognizes late apoptotic cells and promotes phagocytosis of the cells

2006 • 42 citations

Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro

2007 • 34 citations

Characterization of Anti-Phosphatidylcholine Polyreactive Natural Autoantibodies from Normal Human Subjects

2002 • 29 citations

Human natural immunoglobulin M antibodies induce apoptosis of human neuroblastoma cells by binding to a Mr 260,000 antigen.

1999 • 27 citations

The proline-rich acidic protein is epigenetically regulated and inhibits growth of cancer cell lines.

2003 • 21 citations

A SmD Peptide Induces Better Antibody Responses to Other Proteins within the Small Nuclear Ribonucleoprotein Complex than to SmD Protein via Intermolecular Epitope Spreading

2007 • 21 citations

Quantitative Protein Expression Analysis Of CLL B Cells from Mutated and Unmutated IgV_H Subgroups Using Acid-Cleavable Isotope-Coded Affinity Tag Reagents

2005 • 18 citations

What is the current evidence for antigen involvement in the development of chronic lymphocytic leukemia?

2005 • 17 citations

Myelin protein P0-specific IgM producing monoclonal B cell lines were established from polyneuropathy patients with monoclonal gammopathy of undetermined significance (MGUS)

2002 • 9 citations

Intermediate Filaments Vimentin and Desmin Share Epitopes with M 1 Protein of Group A Streptococci

1990 • 6 citations