Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

Nonalcoholic Fatty Liver Disease

2002 • 5,091 citations

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1976 • 4,013 citations

Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities

2001 • 2,021 citations

NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome

2002 • 1,131 citations

Cytokines in Alcoholic and Nonalcoholic Steatohepatitis

2000 • 936 citations

Nonalcoholic fatty liver disease

2002 • 894 citations

Non‐alcoholic fatty liver disease

2002 • 864 citations

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

2000 • 746 citations

Etiopathogenesis of Nonalcoholic Steatohepatitis

2001 • 678 citations

A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections.

1985 • 615 citations

Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression.

1995 • 536 citations

In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases

2002 • 482 citations

Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis.

1994 • 444 citations

Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

2001 • 436 citations

Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo.

1990 • 432 citations

Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation.

1995 • 414 citations

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

1996 • 391 citations

Nonalcoholic steatohepatitis

2001 • 389 citations

Cellular distribution of transforming growth factor-beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis.

1990 • 354 citations

Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver

1996 • 349 citations

Steatohepatitis, Spontaneous Peroxisome Proliferation and Liver Tumors in Mice Lacking Peroxisomal Fatty Acyl-CoA Oxidase

1998 • 341 citations

Transforming growth factor β and the liver

2001 • 340 citations

Stimulation of Lipid Peroxidation or 4-Hydroxynonenal Treatment Increases Procollagen α1 (I) Gene Expression in Human Liver Fat-Storing Cells

1993 • 337 citations

In vivo inhibition of rat stellate cell activation by soluble transforming growth factor β type II receptor: A potential new therapy for hepatic fibrosis

1999 • 325 citations

Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis

1996 • 321 citations

Stimulation of Collagen Gene Expression by Ascorbic Acid in Cultured Human Fibroblasts

1989 • 312 citations

Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3

2001 • 151 citations

Choline-deficiency fatty liver: impaired release of hepatic triglycerides

1968 • 146 citations

Primary structure of human ribosomal protein S14 and the gene that encodes it.

1986 • 138 citations

d-alpha-tocopherol inhibits collagen alpha 1(I) gene expression in cultured human fibroblasts. Modulation of constitutive collagen gene expression by lipid peroxidation.

1991 • 124 citations

Transforming Growth Factor-β Initiates Wound Repair in Rat Liver through Induction of the EIIIA-Fibronectin Splice Isoform

2000 • 89 citations

Drug metabolism in cirrhosis

1986 • 77 citations

The Central Role of Sinusoidal Endothelial Cells in Hepatic Hypoxia–Reoxygenation Injury in the Rat

1996 • 44 citations

Isolation and culture of rat hepatic stellate cells

1998 • 39 citations