Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

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S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1988 • 293 citations

Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism

1994 • 237 citations

A Sensitive New Method for Rapid Detection of Abnormal Methylation Patterns in Global DNA and within CpG Islands

1999 • 204 citations

Changes in methionine adenosyltransferase andS-adenosylmethionine homeostasis in alcoholic rat liver

2000 • 186 citations

Specific loss of the high-molecular-weight form ofS-adenosyl-L-methionine synthetase in human liver cirrhosis

1988 • 168 citations

Disruption of the murine gene encoding phosphatidylethanolamine N -methyltransferase

1997 • 156 citations

Methionine Adenosyltransferase S-Nitrosylation Is Regulated by the Basic and Acidic Amino Acids Surrounding the Target Thiol

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Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells.

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Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes

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Changes in S-adenosylmethionine synthetase in human liver cancer: Molecular characterization and significance

1996 • 136 citations

Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells.

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Purification and comparison of two forms of S‐adenosyl‐<scp>l</scp>‐methionine synthetase from rat liver

1987 • 124 citations

S‐Adenosylmethionine regulatesMAT1AandMAT2Agene expression in cultured rat hepatocytes: a new role for S‐adenosylmethionine in the maintenance of the differentiated status of the liver

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Expression and Functional Interaction of the Catalytic and Regulatory Subunits of Human Methionine Adenosyltransferase in Mammalian Cells

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Differential expression pattern ofS-adenosylmethionine synthetase isoenzymes during rat liver development

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Rate of Disappearance From Plasma of Intravenously Administered Methionine in Patients With Liver Damage

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Changes in methionine adenosyltransferase during liver regeneration in the rat

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Liver‐specific methionine adenosyltransferaseMAT1Agene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications forMAT1Asilencing during transformation

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Regulation of rat liverS-adenosylmethionine synthetase during septic shock: Role of nitric oxide

1997 • 89 citations

Carbon tetrachloride–induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: Effect ofS-adenosylmethionine treatment

1995 • 89 citations

Interaction of liver methionine adenosyltransferase with hydroxyl radical

1997 • 87 citations

Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies

1993 • 82 citations

Molecular cloning and developmental expression of a human kidney S‐adenosylmethionine synthetase

1992 • 76 citations

Cloning and expression of murine S-adenosylmethionine synthetase

1993 • 74 citations

Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer

2001 • 58 citations

Determination of adenosine and s-adenosyl derivatives of sulfur amino acids in rat liver by high-performance liquid chromatography

1985 • 55 citations

Analysis of the 5′ non‐coding region of rat liver S‐adenosylmethionine synthetase mRNA and comparison of the M_r deduced from the cDNA sequence and the purified enzyme

1991 • 52 citations

Differential Effect of Thioacetamide on Hepatic Methionine Adenosyltransferase Expression in the Rat

1999 • 49 citations

Immunohistochemical analysis of rat S‐adenosylmethionine synthetase isozymes in developmental liver

1993 • 46 citations

Copper Binding to Mouse Liver S-Adenosylhomocysteine Hydrolase and the Effects of Copper on Its Levels

1995 • 43 citations

Hysteretic Behavior of Methionine Adenosyltransferase III

2000 • 32 citations

Molecular genetics of hepatic methionine adenosyltransferase deficiency

2000 • 23 citations

Isolation and characterization of a mouse betaine-homocysteine S-methyltransferase gene and pseudogene

2000 • 12 citations