The Relevance of the Dopamine-D1 Receptor in the Cognitive Symptoms of Schizophrenia

Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex

1989 • 2,677 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Neuron Activity Related to Short-Term Memory

1971 • 2,071 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Topography of Cognition: Parallel Distributed Networks in Primate Association Cortex

1988 • 1,649 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

Modulation of memory fields by dopamine Dl receptors in prefrontal cortex

1995 • 1,600 citations

D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

1991 • 1,365 citations

Abnormalities of the Left Temporal Lobe and Thought Disorder in Schizophrenia

1992 • 1,173 citations

Working memory dysfunction in schizophrenia

1994 • 1,066 citations

Anatomical Abnormalities in the Brains of Monozygotic Twins Discordant for Schizophrenia

1990 • 1,009 citations

Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory.

1973 • 1,007 citations

Dopamine receptor pharmacology

1994 • 959 citations

Schizophrenics Show Spatial Working Memory Deficits

1992 • 953 citations

The reduced neuropil hypothesis: a circuit based model of schizophrenia

1999 • 918 citations

Common cortical and subcortical targets of the dorsolateral prefrontal and posterior parietal cortices in the rhesus monkey: evidence for a distributed neural network subserving spatially guided behavior

1988 • 906 citations

Patterns of Cerebral Blood Flow in Schizophrenia

1992 • 905 citations

Abnormally High Neuronal Density in the Schizophrenic Cortex

1995 • 866 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET

1997 • 707 citations

Thalamic Abnormalities in Schizophrenia Visualized Through Magnetic Resonance Image Averaging

1994 • 699 citations

Functional and Anatomical Aspects of Prefrontal Pathology in Schizophrenia

1997 • 665 citations

Physiological Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1988 • 602 citations

Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.

1996 • 599 citations

Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys

1994 • 574 citations

Pronounced Reduction of Total Neuron Number in Mediodorsal Thalamic Nucleus and Nucleus Accumbens in Schizophrenics

1990 • 558 citations

Neuronal and Glial Somal Size in the Prefrontal Cortex

1998 • 530 citations

Further Evidence for Dementia of the Prefrontal Type in Schizophrenia?

1987 • 524 citations

Some Cytoarchitectural Abnormalities of the Entorhinal Cortex in Schizophrenia

1991 • 517 citations

Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain

1995 • 486 citations

Neuropathology of Schizophrenia

1982 • 472 citations

Visuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms

1990 • 446 citations

Three‐dimensional counting: An accurate and direct method to estimate numbers of cells in sectioned material

1988 • 437 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 420 citations

The Cortical Dopamine System: Role in Memory and Cognition

1997 • 396 citations

Distribution of dopaminergic receptors in the primate cerebral cortex: Quantitative autoradiographic analysis using [3H]raclopride, [3H]spiperone and [3H]SCH23390

1991 • 396 citations

Elevated neuronal density in prefrontal area 46 in brains from schizophrenic patients: Application of a three-dimensional, stereologic counting method

1998 • 394 citations

Analysis of the delayed-alternation deficit produced by dorsolateral prefrontal lesions in the rhesus monkey.

1971 • 385 citations

D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines.

1994 • 384 citations

Anteroposterior Gradients in Cerebral Glucose Use in Schizophrenia and Affective Disorders

1984 • 376 citations

Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia

1985 • 373 citations

Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics

1992 • 371 citations

Cellular discharge in the dorsolateral prefrontal cortex of the monkey in cognitive tasks

1982 • 353 citations

Differential effects of amphetamine and neuroleptics on negative Vs. positive symptoms in schizophrenia

1980 • 347 citations

Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?

1973 • 336 citations

Regional distribution of monoamines in the cerebral cortex and subcortical structures of the rhesus monkey: concentrations and in vivo synthesis rates

1979 • 330 citations

Prefrontal unit activity and delayed response: Relation to cue location versus direction of response

1976 • 327 citations

Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primate prefrontal cortex

1990 • 314 citations

Coactivation of prefrontal cortex and inferior parietal cortex in working memory tasks revealed by 2DG functional mapping in the rhesus monkey

1994 • 313 citations

Dopamine receptors in human brain: Autoradiographic distribution of D2 sites

1989 • 298 citations

The cerebral cortex

1976 • 296 citations

Dose-dependent effects of the dopamine D1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys.

1997 • 292 citations

Recent Advances in the Neuropathology of Schizophrenia

1993 • 285 citations

PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride

1987 • 279 citations

Dopamine Receptor mRNA Expression in Human Striatum and Neocortex

1996 • 277 citations

Delay-related activity of prefrontal neurons in rhesus monkeys performing delayed response

1982 • 277 citations

Schizophrenia and the frontal lobe

1988 • 264 citations

Dopamine blockade and clinical response: evidence for two biological subgroups of schizophrenia

1989 • 261 citations

Frontal lobe dysfunctions in schizophrenia—I. Eye movement impairments

1984 • 259 citations

Brain Electrical Activity Mapping (BEAM) in Schizophrenic Patients

1983 • 244 citations

Bilateral frontal lobe disease and selective delayed response deficits in humans.

1986 • 241 citations

Regional Brain Glucose Metabolism in Chronic Schizophrenia

1984 • 237 citations

Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia

1987 • 216 citations

The cerebral cortex: a case for a common site of action of antipsychotics

1998 • 213 citations

Learning and memory in monozygotic twins discordant for schizophrenia

1993 • 212 citations

Neuropathological Studies of Schizophrenia: A Selective Review

1983 • 211 citations

Brain Imaging: Applications in Psychiatry

1988 • 211 citations

Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.

1989 • 208 citations

Positive and Negative Schizophrenic Symptoms and the Role of Dopamine

1980 • 206 citations

Stereoselective binding of 11C-raclopride in living human brain ? a search for extrastriatal central D2-dopamine receptors by PET

1988 • 202 citations

Dysfunctions in Multiple Interrelated Systems as the Neurobiological Bases of Schizophrenic Symptom Clusters

1998 • 198 citations

Dopamine receptors in human brain: Autoradiographic distribution of D1 sites

1989 • 191 citations

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex.

1994 • 175 citations

Word and Tone Working Memory Deficits in Schizophrenia

1998 • 173 citations

Neuropathology of Schizophrenia: Cortex, Thalamus, Basal Ganglia, and Neurotransmitter-specific Projection Systems

1997 • 172 citations

Reversal of asymmetry of the planum temporale in schizophrenia

1995 • 172 citations

Pharmacological profile of SCH39166: a dopamine D1 selective benzonaphthazepine with potential antipsychotic activity.

1988 • 171 citations

Brain imaging: Applications in psychiatry

1987 • 167 citations

Time course of D2-dopamine receptor occupancy examined by PET after single oral doses of haloperidol

1992 • 160 citations

Neurobiological Investigations in Cingulate Cortex of Schizophrenic Brain

1993 • 160 citations

Hypofrontality and cognitive impairment in schizophrenia: Dynamic single-photon tomography and neuropsychological assessment of schizophrenic brain function

1990 • 159 citations

Human dopamine receptor subtypes?in vitro binding analysis using3H-SCH 23390 and3H-raclopride

1988 • 152 citations

Regional Cerebral Blood Flow in Schizophrenics

1983 • 135 citations

Down-regulation of the D1 and D5 dopamine receptors in the primate prefrontal cortex by chronic treatment with antipsychotic drugs.

1997 • 129 citations

Comparison of effects of D-1 and D-2 dopamine receptor agonists on neurons in the rat caudate putamen: an electrophysiological study

1988 • 126 citations

Comparative distributions of dopamine D‐1 and D‐2 receptors in the cerebral cortex of rats, cats, and monkeys

1989 • 121 citations

Partial improvement in negative schizophrenic symptoms after amphetamine

1982 • 119 citations

Regional neuropathology in schizophrenia: Where are we? Where are we going?

1993 • 119 citations

Neurological signs and the positive-negative dimension in schizophrenia

1990 • 115 citations

Delayed response tasks and prefrontal lesions in man—Evidence for self generated patterns of behaviour with poor environmental modulation

1993 • 109 citations

Distribution of Dopamine in the rat cerebral cortex

1976 • 94 citations

Magnetic resonance imaging findings of amygdala- anterior hippocampus shrinkage in male patients with schizophrenia

1994 • 89 citations

Prefrontal unit activity during a delayed oculomotor task in the monkey

1987 • 89 citations

Functional analysis of spatially discriminative neurons in prefrontal cortex of rhesus monkey

1984 • 85 citations

Differential regulation of D2 and D4 dopamine receptor mRNAs in the primate cerebral cortex vs. neostriatum: effects of chronic treatment with typical and atypical antipsychotic drugs.

1997 • 82 citations

Topography Of Cognition: Parallel Distributed Networks In Primate Association Cortex

1988 • 77 citations

Low frontal glucose utilization in chronic schizophrenia: a replication study

1988 • 77 citations

Structural Brain Abnormalities as Indicators of Vulnerability to Schizophrenia

1994 • 74 citations

Recent advances in the pharmacotherapy of schxzophrenia

1994 • 70 citations

Regional Cerebral Blood Flow in Schizophrenic Disorders

1985 • 65 citations

Schizophrenia and the D1 receptor: Focus on negative symptoms

1992 • 57 citations

The Dopamine Hypothesis of Schizophrenia

2016 • 53 citations

Major dopamine innervation of the cortical motor areas in the Cynomolgus monkey. A radioautographic study with comparative assessment of serotonergic afferents

1986 • 52 citations

REGIONAL CEREBRAL BLOOD FLOW IN SCHIZOPHRENICS

1984 • 49 citations

Amphetamine and negative symptoms of schizophrenia

1996 • 48 citations

Comparative characteristics of unit activity in the prefrontal and parietal areas during delayed performance in monkeys

1985 • 44 citations

Biochemical Studies in Schizophrenia

1976 • 39 citations

Elevated neuronal density in prefrontal area 46 in brains from schizophrenic patients: Application of a three‐dimensional, stereologic counting method

1998 • 27 citations

A case study of temporal lobe development in familial schizophrenia

1996 • 21 citations

Bilateral frontal lobe disease and selective delayed response deficits in humans.

1986 • 19 citations

Dopamine Receptors and Cognitive Function in Nonhuman Primates

1997 • 16 citations

Psychopathology and the brain

1993 • 11 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 10 citations

Recent Advances in Pharmacotherapy of Schizophrenia

1993 • 9 citations

Short-term spatiotemporal memory and cortical unit reactions in the monkey.

1981 • 8 citations