Brain Imaging: Applications in Psychiatry

Negative Symptoms in Schizophrenia

1982 • 2,228 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Effect of Chlorpromazine or Haloperidol on Formation of 3‐Methoxytyramine and Normetanephrine in Mouse Brain

1963 • 2,148 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Negative v Positive Schizophrenia

1982 • 2,003 citations

Scale for the Assessment of Negative Symptoms

1982 • 1,883 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

CEREBRAL VENTRICULAR SIZE AND COGNITIVE IMPAIRMENT IN CHRONIC SCHIZOPHRENIA

1976 • 1,235 citations

Positron Emission Tomography Reveals Elevated D ₂ Dopamine Receptors in Drug-Naive Schizophrenics

1986 • 935 citations

The problem of the frontal lobe: A reinterpretation

1971 • 892 citations

Basal Ganglia and Limbic System Pathology in Schizophrenia

1985 • 891 citations

Regional Cerebral Blood Flow Estimated by ¹³³ Xenon Inhalation

1975 • 866 citations

Local Cerebral Glucose Metabolic Rates in Obsessive-Compulsive Disorder

1987 • 855 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

Imaging Dopamine Receptors in the Human Brain by Positron Tomography

1983 • 743 citations

Sexual Dimorphism in the Human Corpus Callosum

1982 • 694 citations

ABNORMALITIES OF CEREBRAL BLOOD FLOW DISTRIBUTION IN PATIENTS WITH CHRONIC SCHIZOPHRENIA

1974 • 673 citations

Development of the corpus callosum and cavum septi in man

1968 • 613 citations

Lateral Cerebral Ventricular Enlargement in Chronic Schizophrenia

1979 • 579 citations

The dopamine hypothesis of schizophrenia: focus on the dopamine receptor

1976 • 543 citations

Quantitative Cytoarchitectural Studies of the Cerebral Cortex of Schizophrenics

1986 • 506 citations

Structural Abnormalities in the Frontal System in Schizophrenia

1986 • 489 citations

Pharmacology of mesocortical dopamine neurons.

1983 • 478 citations

Sex and Handedness Differences in Cerebral Blood Flow During Rest and Cognitive Activity

1982 • 447 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 420 citations

Mapping human visual cortex with positron emission tomography

1986 • 415 citations

Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenia

1983 • 412 citations

Determination of Regional Cerebral Blood Flow by Inhalation of 133-Xenon

1967 • 380 citations

Anteroposterior Gradients in Cerebral Glucose Use in Schizophrenia and Affective Disorders

1984 • 376 citations

Bimodal Distribution of Dopamine Receptor Densities in Brains of Schizophrenics

1984 • 347 citations

Cerebral Ventricular Enlargement in Chronic Schizophrenia

1980 • 328 citations

Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography.

1985 • 304 citations

Brain Function in Psychiatric Disorders

1985 • 297 citations

The application of positron emission tomography to the study of panic disorder

1986 • 295 citations

An Analysis of the Arrangement of Neurons in the Cingulate Cortex of Schizophrenic Patients

1987 • 280 citations

Quantification of Neuroreceptors in the Living Human Brain. I. Irreversible Binding of Ligands

1986 • 279 citations

Left globus pallidus abnormality in never-medicated patients with schizophrenia.

1987 • 269 citations

Structural Abnormalities in the Cerebral Cortex of Chronic Schizophrenic Patients

1979 • 257 citations

Elevation of brain neuroleptic/dopamine receptors in schizophrenia

1980 • 220 citations

Ventricular enlargement in schizophrenia: definition and prevalence

1982 • 215 citations

Regional Brain Function in Schizophrenia

1987 • 211 citations

Ventricular enlargement in teenage patients with schizophrenia spectrum disorder

1983 • 184 citations

HEMISPHERIC SPECIALIZATION IN NORMAL MAN STUDIED BY BILATERAL MEASUREMENTS OF THE REGIONAL CEREBRAL BLOOD FLOW

1975 • 183 citations

Imaging of Neurotransmitter Receptors in the Living Human Brain

1986 • 182 citations

No sex‐related differences in human corpus callosum based on magnetic resonance imagery

1987 • 166 citations

The measurement of regional cerebral clearance rates in man using xenon-133 inhalation and extracranial recording.

1965 • 163 citations

Abnormal Neuroanatomy in a Nonretarded Person With Autism

1987 • 157 citations

Special antagonism of amphetamine-induced abnormal behaviour

1965 • 156 citations

ENZYMATIC OR PHARMACOLOGICAL FIBRINOLYSIS?

1964 • 154 citations

External Imaging of Cerebral Muscarinic Acetylcholine Receptors

1984 • 154 citations

Glucose utilization in the temporal cortex of affectively ill patients: Positron emission tomography

1987 • 153 citations

Quantification of Neuroreceptors in the Living Human Brain. II. Inhibition Studies of Receptor Density and Affinity

1986 • 147 citations

Biological Studies in Schizophrenia

1987 • 138 citations

Cerebral Asymmetries on Magnetic Resonance Imaging

1986 • 137 citations

Strategies for in vivo Measurement of Receptor Binding Using Positron Emission Tomography

1986 • 135 citations

Cerebral Ventricular Size in the Offspring of Schizophrenic Mothers

1984 • 135 citations

Comparison of PET, MRI, and CT with pathology in a proven case of Alzheimer's disease

1986 • 127 citations

Dopamine-β-Hydroxylase Activity and Homovanillic Acid in Spinal Fluid of Schizophrenics with Brain Atrophy

1983 • 125 citations

Regional Cerebral Blood Flow in Schizophrenia

1982 • 117 citations

Brain Organization in Schizophrenia

1986 • 108 citations

Functional and Anatomical Brain Imaging: Impact on Schizophrenia Research

1987 • 102 citations

SPECT Study of Regional Cerebral Blood Flow in Alzheimer Disease

1986 • 94 citations

Whole body insulin resistance in myotonic dystrophy

1984 • 76 citations

Sign language aphasia during left-hemisphere Amytal injection

1986 • 62 citations

A comparison of two cerebral perfusion tracers, N-isopropyl I-123 p-iodoamphetamine and I-123 HIPDM, in the human.

1984 • 53 citations

PET Studies of Glucose Metabolism in Patients with Schizophrenia

1983 • 47 citations

Specific binding of 77Br- -bromospiroperidol in rat brain: A potential tool for gamma ray imaging

1981 • 41 citations

The Dopamine Hypothesis of Schizophrenia

2003 • 15 citations

CT scanning and schizophrenia: a review.

1983 • 14 citations

Regional cerebral blood flow abnormalities in Alzheimer's Disease

1985 • 1 citations