Multiple Hemopoietic Defects and Lymphoid Hyperplasia in Mice Lacking the Transcriptional Activation Domain of the c-Rel Protein

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

NF-κB: Ten Years After

1996 • 3,008 citations

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Role of nitric oxide synthesis in macrophage antimicrobial activity

1991 • 1,547 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

Osteopetrosis in mice lacking NF-κB1 and NF-κB2

1997 • 988 citations

Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity

1996 • 960 citations

Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis

1994 • 883 citations

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family

1995 • 810 citations

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 • 805 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

1995 • 740 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Neutrophil and B Cell Expansion in Mice That Lack the Murine IL-8 Receptor Homolog

1994 • 666 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

NF-κB and Rel Proteins in Innate Immunity

1995 • 435 citations

I kappa B epsilon, a novel member of the Ikappa B family, controls RelA and cRel NF-kappa B activity

1997 • 394 citations

Mechanistic aspects of NF-κB regulation: The emerging role of phosphorylation and proteolysis

1995 • 392 citations

Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers

1996 • 386 citations

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

1992 • 375 citations

Rel/NF-kappaB/IkappaB proteins and cancer.

1996 • 281 citations

REL/NF-κB/IκB Story

1995 • 278 citations

Gastric Hyperplasia and Increased Proliferative Responses of Lymphocytes in Mice Lacking the COOH-terminal Ankyrin Domain of NF-κB2

1997 • 178 citations

The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain.

1990 • 164 citations

Expression of relB transcripts during lymphoid organ development: specific expression in dendritic antigen-presenting cells

1993 • 149 citations

Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor.

1996 • 147 citations

Molecular immunobiology of macrophages: recent progress

1995 • 127 citations

Biology of germinal centers in lymphoid tissue

1994 • 122 citations

The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations.

1996 • 120 citations

Constitutive and inducible Rel/NF-kappa B activities in mouse thymus and spleen.

1994 • 120 citations

B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching.

1996 • 111 citations

RelB, a New Rel Family Transcription Activator That Can Interact with p50-NF-κB

1992 • 110 citations

vRel is an inactive member of the Rel family of transcriptional activating proteins

1991 • 100 citations

Genetic approaches to study Rel/NF-κB/IκB function in mice

1997 • 95 citations

Alterations at the rel locus in human lymphoma.

1991 • 93 citations

Both N- and C-Terminal Domains of RelB Are Required for Full Transactivation: Role of the N-Terminal Leucine Zipper-Like Motif

1993 • 87 citations

B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching.

1997 • 85 citations

Molecular analysis of cutaneous B- and T-cell lymphomas

1995 • 82 citations

The Rel family: models for transcriptional regulation and oncogenic transformation

1992 • 80 citations

Rearranged NFKB-2 Genes in Lymphoid Neoplasms Code for Constitutively Active Nuclear Transactivators

1995 • 80 citations

The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.

1996 • 77 citations

Recovery from Acute Virus Infection

1988 • 70 citations

Isolation and fractionation of mononuclear cell populations.

1995 • 69 citations

Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs

1994 • 63 citations

The Mouse c-rel Protein Has an N-Terminal Regulatory Domain and a C-Terminal Transcriptional Transactivation Domain

1990 • 50 citations

Role of rel family genes in normal and malignant lymphoid cell growth.

1992 • 47 citations

The Rel family of proteins in oncogenesis and differentiation.

1994 • 27 citations

Lipopolysaccharide (LPS) Alters Phosphatidylcholine Metabolism in Elicited Peritoneal Macrophages

1990 • 25 citations

Pulmonary granulomatous vasculitis. Pulmonary granulomatous vasculitis induced in rats by treatment with glucan.

1984 • 20 citations

Germinal centers: A second childhood for lymphocytes

1997 • 15 citations

GTPase enters the ring

1993 • 4 citations