Do we understand the evolution of genomic imprinting?

Parent-Offspring Conflict

1974 • 4,102 citations

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1993 • 2,880 citations

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

1988 • 1,968 citations

Plant Breeding Systems

1997 • 1,877 citations

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

1990 • 1,650 citations

Genetic Conflicts in Human Pregnancy

1993 • 1,234 citations

Genomic imprinting in mammalian development: a parental tug-of-war

1991 • 1,178 citations

Maternal Control of Embryogenesis by MEDEA , a Polycomb Group Gene in Arabidopsis

1998 • 835 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1997 • 753 citations

Essential role of Mash-2 in extraembryonic development

1994 • 612 citations

Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.

1994 • 593 citations

Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest

1998 • 571 citations

Parent-of-origin effects on seed development inArabidopsis thaliana

1998 • 538 citations

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

1997 • 496 citations

Genomic imprinting and the strange case of the insulin-like growth factor II receptor

1991 • 494 citations

Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior

1997 • 478 citations

Gametic Imprinting in Mammals

1995 • 444 citations

Variable and tissue-specific hormone resistance in heterotrimeric G _s protein α-subunit (G _s α) knockout mice is due to tissue-specific imprinting of the G _s α gene

1998 • 406 citations

Genomic imprinting of Mash2, a mouse gene required for trophoblast development

1995 • 366 citations

Population genetic structure and outcrossing rate of Arabidopsis thaliana (L.) Heynh.

1989 • 325 citations

Transactivation of Igf2 in a mouse model of Beckwith–Wiedemann syndrome

1997 • 325 citations

GENOMIC IMPRINTING IN HEREDITARY GLOMUS TUMOURS: EVIDENCE FOR NEW GENETIC THEORY

1989 • 305 citations

Methylation and Imprinting: from Host Defense to Gene Regulation?

1993 • 299 citations

A mouse model for Prader-Willi syndrome imprinting-centre mutations

1998 • 298 citations

Phenotypic alterations in insulin-deficient mutant mice

1997 • 272 citations

The human GNAS1 gene is imprinted and encodes distinct paternally and biallelically expressed G proteins

1998 • 264 citations

Parental antagonism, relatedness asymmetries, and genomic imprinting

1997 • 263 citations

Polar Overdominance at the Ovine callipyge Locus

1996 • 261 citations

Monoallelic Expression of the Interleukin-2 Locus

1998 • 232 citations

Positive selection and the molecular evolution of a gene of male reproduction, Acp26Aa of Drosophila

1997 • 216 citations

Parental imprinting of autosomal mammalian genes

1994 • 208 citations

Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81

1997 • 196 citations

The mouseGtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA

1998 • 156 citations

Identification of the Meg1 / Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver–Russell syndrome gene

1998 • 155 citations

Recombination and the evolution of diploidy.

1992 • 147 citations

Production of Androgenetic Zebrafish (Danio rerio)

1996 • 139 citations

Allelopathy of bacteria in a lattice population: Competition between colicin-sensitive and colicin-producing strains

1998 • 137 citations

Circumsporozoite protein genes of malaria parasites (Plasmodium spp.): evidence for positive selection on immunogenic regions.

1991 • 126 citations

Deficiency of the β3 subunit of the type A γ–aminobutyric acid receptor causes cleft palate in mice

1995 • 122 citations

Molecular and clinical study of 61 Angelman syndrome patients

1994 • 104 citations

The Evolution of Genomic Imprinting

1996 • 96 citations

A candidate model for angelman syndrome in the mouse

1997 • 93 citations

Growth effects of uniparental disomies and the conflict theory of genomic imprinting

1997 • 93 citations

Fine mapping of an imprinted gene for familial nonchromaffin paragangliomas, on chromosome 11q23.

1997 • 88 citations

Genomic imprinting of the human serotonin-receptor (HTR2) gene involved in development of retinoblastoma.

1996 • 76 citations

Gtl2 lacZ , an insertional mutation on mouse Chromosome 12 with parental origin-dependent phenotype

1996 • 71 citations

The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader–Willi syndrome deletion region

1998 • 70 citations

Genomic imprinting in ruminants: allele-specific gene expression in parthenogenetic sheep

1998 • 67 citations

Somatic mutation favors the evolution of diploidy.

1995 • 66 citations

Glomerular-Specific Imprinting of the Mouse Gsα Gene: How Does This Relate to Hormone Resistance in Albright Hereditary Osteodystrophy?

1996 • 55 citations

Genetic Conflicts, Multiple Paternity and the Evolution of Genomic Imprinting

1998 • 54 citations

DNA methylation and genome imprinting in the zebrafish, Danio rerio: some evolutionary ramifications

1997 • 53 citations

Molecular evolution of imprinted genes: no evidence for antagonistic coevolution

1997 • 45 citations

In vitro and early in vivo development of sheep gynogenones and putative androgenones

1998 • 44 citations

The evolution of concerted evolution

1998 • 43 citations

Parent‐of‐origin specific effects on the methylation of a transgene in the zebrafish, Danio rerio

1995 • 40 citations

Evolutionary theories of genomic imprinting

1997 • 35 citations

Molecular Evolution of an Imprinted Gene: Repeatability of Patterns of Evolution Within the Mammalian Insulin-Like Growth Factor Type II Receptor

1998 • 30 citations

Decrease in benzodiazepine receptor binding in a patient with Angelman syndrome detected by iodine-123 iomazenil and single-photon emission tomography

1996 • 29 citations

Association of a redefined proximal mouse chromosome 11 imprinting region and <i>U2afbp-rs/U2af1-rs1</i> expression

1998 • 27 citations

Positive selection and recombination: major molecular mechanisms in colicin diversification

1997 • 26 citations

TheMASProto-oncogene Is Imprinted in Human Breast Tissue

1997 • 22 citations

Analysis of Peg1/Mest imprinting in the mouse

1998 • 22 citations

The evolution of genomic imprinting: Abortion and overshoot explain aberrations

1999 • 21 citations

Delayed development of retinoblastoma associated with loss of a maternal allele on chromosome 13

1995 • 17 citations

Plant development:: Medea's maternal instinct

1998 • 16 citations

DNA methylation and genome imprinting in the zebrafish, Danio rerio: some evolutionary ramifications

1997 • 7 citations

Consequences of genomic imprinting for fetal development

1997 • 6 citations