Transactivation of Igf2 in a mouse model of Beckwith–Wiedemann syndrome

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Molecular cloning: A laboratory manual

1990 • 85,659 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Parental imprinting of the mouse insulin-like growth factor II gene

1991 • 1,773 citations

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

1990 • 1,650 citations

Epigenetic mechanisms of gene regulation

1996 • 1,097 citations

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1987 • 878 citations

Teratocarcinomas and embryonic stem cells: A practical approach

1987 • 768 citations

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

1996 • 767 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1997 • 753 citations

Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.

1994 • 593 citations

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

1997 • 496 citations

Mouse Mutants Lacking the Type 2 IGF Receptor (IGF2R) Are Rescued from Perinatal Lethality inIgf2andIgf1rNull Backgrounds

1996 • 479 citations

Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene

1994 • 471 citations

Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome

1993 • 427 citations

An enhancer deletion affects both H19 and Igf2 expression.

1995 • 398 citations

A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

1994 • 391 citations

An imprinted gene p57KIP2 is mutated in Beckwith–Wiedemann syndrome

1996 • 390 citations

Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements

1997 • 354 citations

Embryological and molecular investigations of parental imprinting on mouse chromosome 7

1991 • 314 citations

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

1992 • 279 citations

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

1994 • 277 citations

Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice.

1994 • 274 citations

Long-range cis effects of ectopic X-inactivation centres on a mouse autosome

1997 • 268 citations

Xist has properties of the X-chromosome inactivation centre

1997 • 248 citations

Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element.

1997 • 243 citations

Imprinting in clusters: lessons from Beckwith-Wiedemann syndrome

1997 • 237 citations

Imprinting mutations in the Beckwith—Wiedemann syndrome suggested by an altered imprinting pattern in the IGF2–H19 domain

1995 • 215 citations

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

1995 • 190 citations

Beckwith-Wiedemann syndrome.

1994 • 184 citations

Somatic overgrowth associated with overexpression of insulin–like growth factor II

1996 • 143 citations

Evolution of Insulin-Like Growth Factor II: Characterization of the Mouse IGF-II Gene and Identification of Two Pseudo-Exons

1990 • 131 citations

Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway

1996 • 127 citations

Imprinting of IGF2 and H19: lack of reciprocity in sporadic Beckwith- Wiedemann syndrome

1997 • 126 citations

Mosaic uniparental disomy in Beckwith-Wiedemann syndrome.

1994 • 94 citations

The cell type-specific IGF2 expression during early human development correlates to the pattern of overgrowth and neoplasia in the Beckwith-Wiedemann syndrome.

1994 • 90 citations

Dynamic methylation adjustment and counting as part of imprinting mechanisms.

1996 • 81 citations

Parental allele specific methylation of the human insulin-like growth factor II gene and Beckwith-Wiedemann syndrome.

1993 • 77 citations

The Insulin-like growth factors : structure and biological functions

1992 • 60 citations

Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast

1996 • 58 citations

Aberrant Methylation of an Imprinted Gene U2af1-rs1(SP2) Caused by Its Own Transgene

1997 • 36 citations

Parental imprinting of an IGF‐2 transgene

1993 • 34 citations

Genomic regions regulating imprinting and insulin‐like growth factor‐II promoter 3 activity in transgenics: novel enhancer and silencer elements

1997 • 19 citations

Nucleotide Sequence of a 28-kb Mouse Genomic Region Comprising the Imprinted Igf2 Gene

1996 • 16 citations

The insulin-like growth factor genes

1992 • 13 citations

Deleted Work

1955 • 0 citations