Apoptosis and necrosis: Mechanisms of cell death induced by cyclosporine A in a renal proximal tubular cell line

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1995 • 5,208 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Features of apoptotic cells measured by flow cytometry

1992 • 1,912 citations

Molecular regulation of apoptosis: Genetic controls on cell death

1993 • 923 citations

Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy

1996 • 443 citations

Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis

1996 • 442 citations

Dicing with death: dissecting the components of the apoptosis machinery

1994 • 363 citations

Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury

1996 • 334 citations

Identification, purification, and characterization of a calcium-dependent endonuclease (NUC18) from apoptotic rat thymocytes. NUC18 is not histone H2B.

1991 • 301 citations

Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.

1994 • 262 citations

Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM

1995 • 253 citations

Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry

1994 • 245 citations

Signal Transduction Pathways in Apoptosis

1996 • 224 citations

Induction of apoptosis in ischemia-reperfusion model of mouse kidney

1998 • 175 citations

Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis

1998 • 170 citations

Native Recombinant Cyclophilins A, B, and C Degrade DNA Independently of Peptidylprolyl cis-trans-Isomerase Activity

1997 • 161 citations

The apoptosis endonucleases: cleaning up after cell death?

1994 • 160 citations

Cell death (apoptosis) in cell culture systems

1995 • 145 citations

A calcium-dependent nuclease from apoptotic rat thymocytes is homologous with cyclophilin. Recombinant cyclophilins A, B, and C have nuclease activity.

1994 • 130 citations

Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis

1997 • 119 citations

Tumourigenesis associated with the p53 tumour suppressor gene

1993 • 115 citations

Apoptosis in disease

1994 • 113 citations

Apoptosis: alive and kicking in 1997

1997 • 104 citations

Regulation of Fas and Fas ligand expression in cultured murine renal cells and in the kidney during endotoxemia

1996 • 104 citations

Programmed cell death : the cellular and molecular biology of apoptosis

1993 • 90 citations

Essential genes that regulate apoptosis

1994 • 87 citations

Expression of Fas antigen and Bcl-2 in human glomerulonephritis

1995 • 83 citations

Anti-Fas antibodies induce cytolysis and apoptosis in cultured human mesangial cells

1996 • 58 citations

Apoptosis during HL‐60 cell differentiation is closely related to a G0/G1 cell cycle arrest

1995 • 57 citations

Potential of monoclonal antibodies to improve therapeutic monitoring of cyclosporine.

1987 • 56 citations

Agonistic anti-Fas antibodies induce glomerular cell apoptosis in mice in vivo

1997 • 52 citations

The Fas/APO-1 receptor and its deadly ligand

1994 • 50 citations

Apoptosis and renal scarring.

1996 • 46 citations

Endonuclease induced DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells

1996 • 44 citations

Neglected opportunities in apoptosis research

1995 • 37 citations

Routine Monitoring of Cyclosporine in Whole Blood and in Kidney Tissue Using High Performance Liquid Chromatography

1986 • 31 citations

Fas-Signaling and Effects on Receptor Tyrosine Kinase Signal Transduction in Human Breast Epithelial Cells

1997 • 24 citations

Role of Apoptosis in Growth and Differentiation of Proximal Tubule Cells in Primary Cultures

1996 • 20 citations

An analysis of the expression of cyclophilin C reveals tissue restriction and an intriguing pattern in the mouse kidney.

1994 • 18 citations

Localization of cyclophilin A and cyclophilin C mRNA in murine kidney using RT-PCR

1994 • 15 citations