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Molecular cloning: A laboratory manual

1990 • 85,659 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

1984 • 1,670 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1989 • 1,087 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription.

1984 • 623 citations

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsA

1991 • 399 citations

Role of endothelin in cyclosporine-induced glomerular dysfunction

1990 • 368 citations

High brain densities of the immunophilin FKBP colocalized with calcineurin

1992 • 340 citations

Isolation and amino acid sequence of cyclophilin.

1986 • 294 citations

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

1991 • 248 citations

Polymerase chain reaction localization of constitutive nitric oxide synthase and soluble guanylate cyclase messenger RNAs in microdissected rat nephron segments.

1992 • 247 citations

Cyclophilin: distribution and variant properties in normal and neoplastic tissues.

1986 • 214 citations

Pharmacology of cyclosporine (sandimmune). IV. Pharmacological properties in vivo.

1990 • 174 citations

EVIDENCE THAT RENAL PROSTAGLANDIN AND THROMBOXANE PRODUCTION IS STIMULATED IN CHRONIC CYCLOSPORINE NEPHROTOXICITY

1987 • 167 citations

Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding

1990 • 160 citations

Nucleotide sequence of a cDNA coding for mouse cyclophilin

1990 • 111 citations

Nephron segment-specific inhibition of Na+/K+-ATPase activity by cyclosporin A

1993 • 100 citations

Cyclosporin receptors on human lymphocytes.

1982 • 89 citations

Morphology of cyclosporine nephrotoxicity in the rat.

1986 • 79 citations

Detection of specific mRNAs in single nephron segments by use of the polymerase chain reaction

1990 • 67 citations

Renal injury induced by long-term administration of cyclosporin A to rats.

1987 • 63 citations

RT-PCR microlocalization of mRNA for guanylyl cyclase-coupled ANF receptor in rat kidney

1991 • 62 citations

THE EFFECT OF SALT INTAKE ON CYCLOSPORINE-INDUCED IMPAIRMENT OF RENAL FUNCTION IN RATS

1984 • 44 citations

Mechanisms of cyclosporine A toxicity in defined cultures of renal tubule epithelia: A role for cysteine proteases

1991 • 36 citations

Pathophysiology of cyclosporine nephrotoxicity: role of eicosanoids.

1988 • 27 citations

Cyclosporine as an immunosuppressive agent for autoimmune disease: theoretical concepts and therapeutic strategies.

1988 • 22 citations

Pathophysiology of cyclosporine nephrotoxicity: role of eicosanoids.

1988 • 20 citations

Chronic Ciclosporin Nephrotoxicity: A Rabbit Model

1991 • 16 citations

Cyclosporine Nephropathy: Morphometric Analysis of the Medullary Thick Ascending Limb

1992 • 12 citations