A Human Telomeric Protein

Basic local alignment search tool

1990 • 87,358 citations

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

The RNA Component of Human Telomerase

1995 • 2,243 citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 • 2,096 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Structure and variability of human chromosome ends.

1990 • 833 citations

Hypervariable ultra-long telomeres in mice

1990 • 612 citations

Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices

1994 • 484 citations

RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability

1990 • 436 citations

Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen

1987 • 420 citations

The p150 and p60 subunits of chromatin assemblyfactor I: A molecular link between newly synthesized histories and DNA replication

1995 • 373 citations

Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes

1994 • 360 citations

Runaway telomere elongation caused by telomerase RNA gene mutations

1995 • 338 citations

Human telomeres are attached to the nuclear matrix.

1992 • 334 citations

Involvement of the Silencer and UAS Binding Protein RAP1 in Regulation of Telomere Length

1990 • 326 citations

A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere

1991 • 313 citations

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

1993 • 283 citations

Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast

1992 • 280 citations

RAP1: a protean regulator in yeast

1994 • 273 citations

A mammalian factor that binds telomeric TTAGGG repeats in vitro.

1992 • 250 citations

Human telomeres: fusion and interstitial sites

1989 • 248 citations

C-Terminal Truncation of RAP1 Results in the Deregulation of Telomere Size, Stability, and Function in Saccharomyces cerevisiae

1992 • 233 citations

A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain.

1993 • 230 citations

Variability at the Telomeres of the Human X/Y Pseudoautosomal Region

1986 • 229 citations

Unusual chromatin in human telomeres.

1994 • 219 citations

Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.

1991 • 218 citations

Identification of essential components of the S. cerevisiae kinetochore

1993 • 198 citations

Stringent sequence requirements for the formation of human telomeres.

1994 • 190 citations

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

1988 • 190 citations

A novel DNA binding protein with homology to Myb oncoproteins containing only one repeat can function as a transcriptional activator.

1994 • 181 citations

Extensive telomere repeat arrays in mouse are hypervariable

1990 • 177 citations

Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells.

1994 • 168 citations

Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes.

1995 • 161 citations

Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions.

1990 • 146 citations

Specific DNA Binding by c-Myb: Evidence for a Double Helix-Turn-Helix-Related Motif

1991 • 143 citations

C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae.

1992 • 141 citations

Structure(?) and function of acidic transcription activators

1993 • 136 citations

Identification of novel centromere/kinetochore-associated proteins using monoclonal antibodies generated against human mitotic chromosome scaffolds.

1991 • 116 citations

Unusual Chromatin in Human Telomeres

1994 • 88 citations

A zinc finger protein, essential for chromosome segregation, constitutes a putative DNA binding subunit of the Saccharomyces cerevisiae kinetochore complex, Cbf3.

1994 • 80 citations

Microbore reversed-phase high-performance liquid chromatographic purification of peptides for combined chemical sequencing-laser-desorption mass spectrometric analysis

1994 • 71 citations

Improvements in Microsequencer Performance for Low Picomole Sequence Analysis

1994 • 66 citations

High‐Sensitivity sequencing of large proteins: Partial structure of the rapamycin‐fkbp12 target

1994 • 53 citations

Ultrastructural localization of epidermal growth factor (EGF)-receptor transcripts in the cell nucleus using pre-embedding in situ hybridization in combination with ultra-small gold probes and silver enhancement

1994 • 28 citations