RAP1: a protean regulator in yeast

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

1990 • 1,343 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

1992 • 480 citations

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage.

1993 • 463 citations

RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability

1990 • 436 citations

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

1993 • 392 citations

A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation

1987 • 332 citations

Involvement of the Silencer and UAS Binding Protein RAP1 in Regulation of Telomere Length

1990 • 326 citations

Connections Between Transcriptional Activators, Silencers, and Telomeres as Revealed by Functional Analysis of a Yeast DNA-Binding Protein

1988 • 284 citations

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

1993 • 283 citations

C-Terminal Truncation of RAP1 Results in the Deregulation of Telomere Size, Stability, and Function in Saccharomyces cerevisiae

1992 • 233 citations

A general upstream binding factor for genes of the yeast translational apparatus.

1985 • 222 citations

Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.

1991 • 218 citations

Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast

1993 • 207 citations

Distortion of the DNA Double Helix by RAP1 at Silencers and Multiple Telomeric Binding Sites

1993 • 198 citations

Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae.

1991 • 181 citations

Similarity Between the Transcriptional Silencer Binding Proteins ABF1 and RAP1

1989 • 180 citations

A yeast Telomere Binding Activity binds to two related telomere sequence motifs and is indistinguishable from RAPT

1989 • 178 citations

RAP1 protein activates and silences transcription of mating-type genes in yeast.

1991 • 170 citations

Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity.

1994 • 162 citations

Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein.

1988 • 157 citations

RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.

1991 • 147 citations

A yeast ARS-binding protein activates transcription synergistically in combination with other weak activating factors.

1990 • 146 citations

An Origin of DNA Replication and a Transcription Silencer Require a Common Element

1992 • 143 citations

C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae.

1992 • 141 citations

Tripartite Upstream Promoter Element Essential for Expression of Saccharomyces cerevisiae Ribosomal Protein Genes

1986 • 136 citations

A synthetic silencer mediates SIR-dependent functions in Saccharomyces cerevisiae.

1991 • 105 citations

GCR1, a transcriptional activator in Saccharomyces cerevisiae, complexes with RAP1 and can function without its DNA binding domain.

1993 • 95 citations

Epigenetic Switching of Transcriptional States: cis- and trans-Acting Factors Affecting Establishment of Silencing at the HMR Locus in Saccharomyces cerevisiae

1993 • 94 citations

Silencers, silencing, and heritable transcriptional states.

1992 • 78 citations

Role of GCR2 in transcriptional activation of yeast glycolytic genes.

1992 • 76 citations

Dissection of a Carboxy-Terminal Region of the Yeast Regulatory Protein RAP1 with Effects on Both Transcriptional Activation and Silencing

1992 • 76 citations

Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae.

1993 • 71 citations

Contacts between the factor TUF and RPG sequences.

1990 • 68 citations

Analysis of upstream activation sites of yeast ribosomal protein genes

1987 • 66 citations

Efficient Transcription of the Glycolytic Gene ADH1 and Three Translational Component Genes Requires the GCR1 Product, Which Can Act Through TUF/GRF/RAP Binding Sites

1990 • 65 citations

Tripartite upstream promoter element essential for expression of Saccharomyces cerevisiae ribosomal protein genes.

1986 • 63 citations

The Role of RAP1 in the Regulation of the MATα Locus

1991 • 49 citations

Dissection of a carboxy-terminal region of the yeast regulatory protein RAP1 with effects on both transcriptional activation and silencing.

1992 • 46 citations

Mutational analysis of the upstream activation site of yeast ribosomal protein genes

1989 • 43 citations

Efficient transcription of the glycolytic gene ADH1 and three translational component genes requires the GCR1 product, which can act through TUF/GRF/RAP binding sites.

1990 • 39 citations

Global regulators of chromosome function in yeast

1992 • 26 citations

The role of RAP1 in the regulation of the MAT alpha locus.

1991 • 19 citations