C-Terminal Truncation of RAP1 Results in the Deregulation of Telomere Size, Stability, and Function in Saccharomyces cerevisiae

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1989 • 8,705 citations

Methods in yeast genetics

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1988 • 4,905 citations

Current protocols in molecular biology

1988 • 4,543 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1989 • 1,607 citations

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1989 • 1,509 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

1990 • 1,343 citations

The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1987 • 1,127 citations

A mutant with a defect in telomere elongation leads to senescence in yeast

1989 • 905 citations

The complete DNA sequence of yeast chromosome III

1992 • 851 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

Cloning yeast telomeres on linear plasmid vectors

1982 • 625 citations

STRUCTURE AND FUNCTION OF TELOMERES

1989 • 604 citations

DNA sequences of telomeres maintained in yeast

1984 • 552 citations

Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss

1985 • 486 citations

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

1992 • 480 citations

RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability

1990 • 436 citations

Functional Evidence for an RNA Template in Telomerase

1990 • 392 citations

Human telomeres are attached to the nuclear matrix.

1992 • 334 citations

Involvement of the Silencer and UAS Binding Protein RAP1 in Regulation of Telomere Length

1990 • 326 citations

Organization of DNA sequences and replication origins at yeast telomeres

1983 • 318 citations

Telomere proteins: Specific recognition and protection of the natural termini of Oxytricha macronuclear DNA

1986 • 305 citations

Connections Between Transcriptional Activators, Silencers, and Telomeres as Revealed by Functional Analysis of a Yeast DNA-Binding Protein

1988 • 284 citations

Saccharomyces telomeres assume a non-nucleosomal chromatin structure.

1992 • 275 citations

The genetic control of direct-repeat recombination in Saccharomyces: the effect of rad52 and rad1 on mitotic recombination at GAL10, a transcriptionally regulated gene.

1989 • 244 citations

Identification of yeast mutants with altered telomere structure.

1986 • 243 citations

Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication

1987 • 238 citations

Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.

1991 • 218 citations

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

1989 • 184 citations

A unique pathway of double-strand break repair operates in tandemly repeated genes.

1991 • 179 citations

A yeast Telomere Binding Activity binds to two related telomere sequence motifs and is indistinguishable from RAPT

1989 • 178 citations

Telomere terminal transferase activity in the hypotrichous ciliateOxytricha novaand a model for replication of the ends of linear DNA molecules

1988 • 171 citations

RAP1 protein activates and silences transcription of mating-type genes in yeast.

1991 • 170 citations

Generation of telomere-length heterogeneity in Saccharomyces cerevisiae.

1988 • 170 citations

CDC17: An essential gene that prevents telomere elongation in yeast

1985 • 156 citations

Telomeric DNA-protein interactions of Oxytricha macronuclear DNA.

1987 • 152 citations

Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.

1988 • 148 citations

Chromosome length controls mitotic chromosome segregation in yeast

1986 • 144 citations

Chromatin structure of the molecular ends of oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex

1984 • 139 citations

Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae.

1988 • 135 citations

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers.

1989 • 118 citations

Telomere structure in Euplotes crassus: characterization of DNA-protein interactions and isolation of a telomere-binding protein.

1990 • 108 citations

Genetic control of chromosome length in yeast.

1985 • 89 citations

Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena.

1981 • 88 citations

A yeast protein that binds to vertebrate telomeres and conserved yeast telomeric junctions.

1991 • 80 citations

A Unique Pathway of Double-Strand Break Repair Operates in Tandemly Repeated Genes

1991 • 80 citations

Dissection of a Carboxy-Terminal Region of the Yeast Regulatory Protein RAP1 with Effects on Both Transcriptional Activation and Silencing

1992 • 76 citations

Characterisation of the DNA binding domain of the yeast RAP1 protein

1990 • 70 citations

Chromatin structure of the telomeric region and 3'-nontranscribed spacer of Tetrahymena ribosomal RNA genes.

1986 • 64 citations

Assembly and self-association of Oxytricha telomeric nucleoprotein complexes

1989 • 58 citations

Oxytrichatelomeric nucleoprotein complexes reconstituted with synthetic DNA

1989 • 50 citations

The Role of RAP1 in the Regulation of the MATα Locus

1991 • 49 citations

Vanadate-resistant mutants of Saccharomyces cerevisiae show alterations in protein phosphorylation and growth control.

1990 • 46 citations

Transverse alternating electrophoresis

1988 • 45 citations

Nucleic acid specificity of a vertebrate telomere-binding protein: evidence for G-G base pair recognition at the core-binding site.

1992 • 44 citations

Characterization of a Telomere-Binding Protein from Physarum polycephalum

1991 • 38 citations

The estimation of mutation rates from incompletely tested gametes, and the detection of mutations in mammals

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Transverse Alternating-Field Electrophoresis

2003 • 12 citations