Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRβ locus rearrangements and putative new T-cell oncogenes
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References (38)
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 • 2,631 citations
Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL).
1995 • 1,374 citations
Acute Lymphoblastic Leukemia
2004 • 1,130 citations
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
2002 • 1,112 citations
Proposals for immunological classification of acute leukemias.
1995 • 543 citations
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
2004 • 424 citations
Rationale and design of Total Therapy Study XV for newly diagnosed childhood acute lymphoblastic leukemia
2004 • 378 citations
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL)
2005 • 362 citations
Clinical Significance of Cytogenetic Abnormalities in Adult Acute Lymphoblastic Leukemia
1998 • 313 citations
Gene for α-Chain of Human T-Cell Receptor: Location on Chromosome 14 Region Involved in T-Cell Neoplasms
1985 • 300 citations
Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias [see comments]
1994 • 280 citations
Clinical Significance of Cytogenetic Abnormalities in Adult Acute Lymphoblastic Leukemia
1998 • 276 citations
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia
2001 • 262 citations
Biology and Treatment of Childhood T-Lineage Acute Lymphoblastic Leukemia
1998 • 173 citations
CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCR lineage
2003 • 158 citations
Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A Collaborative Study of the Group Francais de Cytogenetique Hematologique [published erratum appears in Blood 1996 Oct 1;88(7):2818]
1996 • 134 citations
Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia
2003 • 129 citations
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes
2005 • 129 citations
Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes.
1990 • 127 citations
New recurring cytogenetic abnormalities and association of blast cell karyotypes with prognosis in childhood T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group report of 343 cases
2000 • 121 citations
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
2005 • 117 citations
Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia.
2005 • 113 citations
Childhood Acute Lymphoblastic Leukemia With the MLL-ENL Fusion and t(11;19)(q23;p13.3) Translocation
1999 • 111 citations
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using m‐FISH
2001 • 110 citations
Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci
2002 • 101 citations
The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene
2000 • 87 citations
CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono‐ and bi‐allelic 9p21 deletions in childhood acute lymphoblastic leukemia
2003 • 87 citations
The use of whole genome amplification in the study of human disease
2004 • 86 citations
T Cell Receptor Gene Trans-Rearrangements: Chimeric γ-δ Genes in Normal Lymphoid Tissues
1989 • 58 citations
7q32-q36 translocations in childhood T cell leukemia: cytogenetic evidence for involvement of the T cell receptor beta-chain gene
1987 • 53 citations
Cytogenetic analysis in relapsed childhood acute lymphoblastic leukemia.
1992 • 41 citations
Translocations involving 9p and/or 12p in acute lymphoblastic leukemia
1992 • 30 citations
t(10;11)(p13–14;q14–21): A New Recurrent Translocation in T‐Cell Acute Lymphoblastic Leukemias
1991 • 28 citations
Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization.
2005 • 17 citations
Cytogenetic Studies in T-Cell Acute Lymphoblastic Leukemia (1981 – 2002)
2003 • 13 citations
Molecular analysis of T-cell receptor transcripts in a human T-cell leukemia bearing a t(1;14) and an inv(7); cell surface expression of a TCR-beta chain in the absence of alpha chain.
1993 • 12 citations
Alternative origin of p13MTCP1-encoding transcripts in mature T-cell proliferations with t(X;14) translocations
1997 • 11 citations
HOX genes: not just myeloid oncogenes any more
2005 • 9 citations