Methylphenidate for the treatment of depressive symptoms, including fatigue and apathy, in medically ill older adults and terminally ill adults

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1965 • 430 citations

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Methylphenidate therapy improves cognition, mood, and function of brain tumor patients.

1998 • 377 citations

Depression in hospitalized older patients with congestive heart failure

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2002 • 355 citations

Imaging the Effects of Methylphenidate on Brain Dopamine: New Model on Its Therapeutic Actions for Attention-Deficit/Hyperactivity Disorder

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1992 • 287 citations

Drug therapy for the management of cancer-related fatigue

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1992 • 262 citations

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1996 • 218 citations

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2004 • 216 citations

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2004 • 209 citations

A Randomized, Double-blind, Placebo-Controlled Trial of Psychostimulants for the Treatment of Fatigue in Ambulatory Patients With Human Immunodeficiency Virus Disease

2001 • 206 citations

Patient-Controlled Methylphenidate for the Management of Fatigue in Patients With Advanced Cancer: A Preliminary Report

2003 • 206 citations

A Phase III, Double-Blind, Placebo-Controlled Prospective Randomized Clinical Trial of d-Threo-Methylphenidate HCl in Brain Tumor Patients Receiving Radiation Therapy

2007 • 203 citations

Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury

2005 • 199 citations

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1997 • 193 citations

Methylphenidate associated with narcotics for the treatment of cancer pain.

1987 • 185 citations

Stimulant treatment for the neurobehavioural sequelae of traumatic brain injury

1988 • 172 citations

Neuropsychological effects of methylphenidate in patients receiving a continuous infusion of narcotics for cancer pain

1992 • 159 citations

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1992 • 157 citations

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1997 • 153 citations

Psychostimulants for depression

2008 • 153 citations

Methylphenidate improves fatigue scores in Parkinson disease: A randomized controlled trial

2007 • 139 citations

Methylphenidate for the Treatment of Apathy in Alzheimer Disease

2008 • 139 citations

Interferon-Induced Fatigue in Patients With Melanoma: A Pilot Study of Exercise and Methylphenidate

2002 • 138 citations

Methylphenidate for fatigue in advanced cancer: A prospective open-label pilot study

2001 • 137 citations

A Randomized, Double-blind, Placebo-controlled Trial of Augmentation With an Extended Release Formulation of Methylphenidate in Outpatients With Treatment-Resistant Depression

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1971 • 131 citations

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1995 • 121 citations

Psychostimulants for Depression in Hospitalized Cancer Patients

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1992 • 120 citations

Methylphenidate for depressive disorders in cancer patients

1987 • 119 citations

Double-blind, placebo-controlled trial of methylphenidate in older, depressed, medically ill patients

1995 • 116 citations

Withdrawn, Apathetic Geriatric Patients Responsive to Methylphenidate

1975 • 115 citations

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1993 • 111 citations

A double-blind controlled study of methylphenidate treatment in closed head injury

1993 • 110 citations

Double-Blind, Randomized Trial of Dexmethylphenidate Hydrochloride for the Treatment of Sarcoidosis-Associated Fatigue

2008 • 104 citations

Combined MAOI, TCA, and direct stimulant therapy of treatment-resistant depression.

1985 • 104 citations

A phase II study of methylphenidate for depression in advanced cancer

2001 • 104 citations

Methylphenidate hydrochloride improves cognitive function in patients with advanced cancer and hypoactive delirium: a prospective clinical study.

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Treatment of Chronic Closed Head Injury with Psychostimulant Drugs: A Controlled Case Study and an Appropriate Evaluation Procedure

1987 • 101 citations

Methylphenidate and seizure frequency in brain injured patients with seizure disorders.

1992 • 99 citations

Methylphenidate treatment of negative symptoms in patients with dementia

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1989 • 96 citations

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1989 • 95 citations

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Methylphenidate-Enhanced Antidepressant Response to Citalopram in the Elderly: A Double-Blind, Placebo-Controlled Pilot Trial

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Psychostimulants for Secondary Depression in Medical Illness

1991 • 87 citations

Combined Treatment With Methylphenidate and Citalopram for Accelerated Response in the Elderly

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1992 • 82 citations

Effects of Methylphenidate in HIV-Related Depression: A Comparative Trial with Desipramine

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Can Methylphenidate Reduce Fall Risk in Community‐Living Older Adults? A Double‐Blind, Single‐Dose Cross‐Over Study

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Potentiation of Opioid Analgesia by Psychostimulant Drugs

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A phase II study of methylphenidate for the treatment of fatigue

2005 • 76 citations

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1994 • 76 citations

Psychostimulants in post-stroke depression

1991 • 73 citations

Use of methylphenidate in patients with cancer

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Stereoselective disposition of methylphenidate in children with attention-deficit disorder.

1987 • 68 citations

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METHYLPHENIDATE IN STROKE PATIENTS WITH DEPRESSION

1992 • 55 citations

An expert opinion on methylphenidate treatment for attention deficit hyperactivity disorder in pediatric patients with epilepsy

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Enantioselective Aspects of the Disposition of dl-threo-Methylphenidate after the Administration of a Sustained-Release Formulation to Children with Attention Deficit-Hyperactivity Disorder

1989 • 53 citations

Methylphenidate in depressed medically ill patients.

1991 • 52 citations

Successful methylphenidate treatment of apathy after subcortical infarcts

1995 • 51 citations

Successful palliation of hypoactive delirium due to multi-organ failure by oral methylphenidate

2000 • 51 citations

Use of a Depression Screening Tool and a Fluoxetine-Based Algorithm to Improve the Recognition and Treatment of Depression in Cancer Patients

2002 • 48 citations

Treatment of Depression With Methylphenidate in Patients Difficult to Wean From Mechanical Ventilation in the Intensive Care Unit

2000 • 47 citations

An Evaluation of the Effects of Methylphenidate on Outcomes in Adult Epilepsy Patients

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Single-Dose Pharmacokinetics of Methylphenidate in CYP2D6 Extensive and Poor Metabolizers

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Psychostimulant Treatment of Geriatric Depressive Disorders Secondary to Medical Illness

1990 • 45 citations

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Treatment of Apathy With Methylphenidate

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The effect of methylphenidate on test performance in the cognitively impaired aged

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Methylphenidate May Treat Apathy Independent of Depression

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1992 • 32 citations

Elderly depressed females as a possible subgroup of patients responsive to methylphenidate.

1986 • 32 citations

Psychostimulants and delirium in patients receiving palliative care

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Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD

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Does Chirality Matter?

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Effects of methylphenidate on cognition and apathy in normal pressure hydrocephalus: A case study and review

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Central Nervous System Stimulants as

1992 • 25 citations

Central nervous system stimulants as symptomatic treatments for AIDS-related neuropsychiatric impairment.

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Methylphenidate Improves HIV-1-Associated Cognitive Slowing

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Methylphenidate in Post Liver Transplant Patients

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DOUBLE-BLIND EVALUATION OF METHYLPHENIDATE (RITALIN) HYDROCHLORIDE

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Long-term Methylphenidate Use in the Medically Ill Patient With Organic Mood Syndrome

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Treatment of Apathy With Methylphenidate

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Methylphenidate in mildly depressed outpatients

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Methylphenidate in mild depression: a double-blind controlled trial.

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Cerebral vasculitis following oral methylphenidate intake in an adult: A case report

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Algorithm for the treatment of major depression in patients with advanced cancer.

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Comparison between methylphenidate and placebo as adjuvant in care and rehabilitation of geriatric patients.

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Protracted Administration of Methylphenidate (Ritalin)

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Anti-Depressant Chemotherapy, 1965 Rapid Response to Serotonin Precursor Potentiated by Ritalin

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Supraventricular Tachycardia Associated With Methylphenidate Treatment in a Heart Transplant Recipient

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Methylphenidate in a Patient with Depression and Respiratory Insufficiency

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Methylphenidate Treatment of Minor Depression in Very Old Patients

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NARCOTICS PLUS METHYLPHENIDATE (RITALIN) FOR ADVANCED CANCER PAIN

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Some problems concerning the apparent multiplicity of monoamine oxidase [proceedings].

1977 • 2 citations