Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: Further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Smoothing and Differentiation of Data by Simplified Least Squares Procedures.

1964 • 18,746 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

[64] The measurement of membrane potential and ΔpH in cells, organelles, and vesicles

1979 • 807 citations

Molecular cloning, primary structure, and expression of the human growth factor-activatable antiporter

1989 • 774 citations

The multidrug transporter, a double-edged sword.

1988 • 763 citations

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.

1970 • 752 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Is the multidrug transporter a flippase?

1992 • 720 citations

Primary structure and transmembrane orientation of the murine anion exchange protein

1985 • 552 citations

Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport.

1984 • 434 citations

36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO

1991 • 432 citations

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling.

1986 • 342 citations

Lymphocyte membrane potential assessed with fluorescent probes

1980 • 336 citations

Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein

1992 • 328 citations

Cloning and characterization of band 3, the human erythrocyte anion-exchange protein (AE1).

1989 • 308 citations

Characterization of a new drug-resistant human myeloma cell line that expresses P-glycoprotein.

1986 • 275 citations

Immunohistochemical detection and quantitation of P-glycoprotein in multiple drug-resistant human myeloma cells: association with level of drug resistance and drug accumulation

1989 • 212 citations

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil.

1988 • 205 citations

cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger.

1990 • 191 citations

Ion transport, membrane potential, and cytoplasmic pH in lymphocytes: changes during activation

1989 • 187 citations

Cloning and characterization of a murine band 3-related cDNA from kidney and from a lymphoid cell line.

1988 • 186 citations

Dual-wavelength ratiometric fluorescence measurements of membrane potential

1989 • 179 citations

Cloning and structural characterization of a human non-erythroid band 3-like protein.

1986 • 155 citations

Increased Cytosolic pH in Multidrug-Resistant Human Lung Tumor Cells: Effect of Verapamil

1989 • 120 citations

Phospholipid asymmetry in large unilamellar vesicles induced by transmembrane pH gradients

1989 • 113 citations

Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye.

1990 • 104 citations

Analysis of the steady-state and initial rate of doxorubicin efflux from a series of multidrug resistant cells expressing different levels of P-glycoprotein

1992 • 102 citations

Cellular transport of anthracyclines by passive diffusion

1985 • 102 citations

Lipophilic cations: a group of model substrates for the multidrug-resistance transporter

1992 • 94 citations

Energy-dependent reduced drug binding as a mechanism of Vinca alkaloid resistance in human leukemic lymphoblasts.

1983 • 82 citations

Ion selectivity of temperature-induced and electric field induced pores in dipalmitoylphosphatidylcholine vesicles

1985 • 74 citations

Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells

1990 • 72 citations

Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene.

1989 • 64 citations

Membrane potential differences between adriamycin-sensitive and -resistant cells as measured by flow cytometry

1989 • 57 citations

Correction of altered plasma membrane potentials

1988 • 47 citations

Unidirectional K⁺ fluxes in rat thymocytes stimulated by concanavalin A

1976 • 38 citations