Essential role for the Menkes ATPase in activation of extracellular superoxide dismutase: implication for vascular oxidative stress

Superoxide Dismutase

1969 • 12,578 citations

Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

1999 • 1,573 citations

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

2003 • 1,435 citations

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

2003 • 1,341 citations

Oxidative Stress and Cardiovascular Injury

2003 • 916 citations

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1996 • 868 citations

Metallochaperones, an Intracellular Shuttle Service for Metal Ions

2000 • 790 citations

Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

2003 • 761 citations

Oxidative Stress and Cardiovascular Injury

2003 • 719 citations

Metal Ion Chaperone Function of the Soluble Cu(I) Receptor Atx1

1997 • 675 citations

Superoxide Production in Vascular Smooth Muscle Contributes to Oxidative Stress and Impaired Relaxation in Atherosclerosis

1998 • 631 citations

A Role for the Saccharomyces cerevisiae ATX1 Gene in Copper Trafficking and Iron Transport

1997 • 403 citations

Extracellular superoxide dismutase and cardiovascular disease

2002 • 342 citations

The molecular basis of copper-transport diseases

2001 • 298 citations

Interactions Between Nitric Oxide and Lipid Oxidation Pathways

2001 • 258 citations

Functional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation

1998 • 225 citations

Extracellular Superoxide Dismutase Is a Major Determinant of Nitric Oxide Bioavailability

2003 • 224 citations

The Menkes copper transporter is required for the activation of tyrosinase

2000 • 213 citations

Biochemical characterization and intracellular localization of the Menkes disease protein

1996 • 205 citations

Validation of Lucigenin as a Chemiluminescent Probe to Monitor Vascular Superoxide as Well as Basal Vascular Nitric Oxide Production

1999 • 187 citations

Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase

2003 • 183 citations

Extracellular Superoxide Dismutase (EC-SOD) Binds to Type I Collagen and Protects Against Oxidative Fragmentation

2004 • 176 citations

Vitamin E Inhibits Abdominal Aortic Aneurysm Formation in Angiotensin II–Infused Apolipoprotein E–Deficient Mice

2005 • 167 citations

Vascular expression of extracellular superoxide dismutase in atherosclerosis.

1998 • 159 citations

Gene Transfer of Extracellular Superoxide Dismutase Reduces Arterial Pressure in Spontaneously Hypertensive Rats

2003 • 156 citations

Mechanisms of Copper Incorporation into Human Ceruloplasmin

2002 • 152 citations

HAH1 Is a Copper-binding Protein with Distinct Amino Acid Residues Mediating Copper Homeostasis and Antioxidant Defense

1998 • 147 citations

Genetically Reduced Antioxidative Protection and Increased Ischemic Heart Disease Risk

2003 • 146 citations

A murine model of Menkes disease reveals a physiological function of metallothionein

1996 • 134 citations

Copper Induces the Assembly of a Multiprotein Aggregate Implicated in the Release of Fibroblast Growth Factor 1 in Response to Stress

2001 • 114 citations

Fibulin-5 Is a Novel Binding Protein for Extracellular Superoxide Dismutase

2004 • 102 citations

pH-dependent migration of copper(II) to the vacant zinc-binding site of zinc-free bovine erythrocyte superoxide dismutase

1979 • 96 citations

Menkes Protein Contributes to the Function of Peptidylglycine α-Amidating Monooxygenase

2002 • 94 citations

Spontaneous aortic aneurysms in blotchy mice.

1975 • 90 citations

Functional analysis and intracellular localization of the human menkes protein (MNK) stably expressed from a cDNA construct in Chinese hamster ovary cells (CHO-K1)

1998 • 89 citations

Menkes syndrome and animal models

1998 • 88 citations

IV. Wilson’s disease and Menkes disease

1999 • 81 citations

Supplying Copper to the Cuproenzyme Peptidylglycine α-Amidating Monooxygenase

2003 • 78 citations

Role of Antioxidant-1 in Extracellular Superoxide Dismutase Function and Expression

2005 • 75 citations

Furin Proteolytically Processes the Heparin-binding Region of Extracellular Superoxide Dismutase

2002 • 67 citations

Intracellular localization and loss of copper responsiveness of Mnk, the murine homologue of the Menkes protein, in cells from blotchy (Mo blo) and brindled (Mo br) mouse mutants

1999 • 60 citations

Localization of presenilin–nicastrin complexes and γ‐secretase activity to the trans‐Golgi network

2003 • 59 citations

Functional Evaluation of Nonphagocytic NAD(P)H Oxidases

2002 • 52 citations

A Novel Role for the Immunophilin FKBP52 in Copper Transport

2004 • 46 citations

Nitric oxide, free radicals and cell signalling in cardiovascular disease

1997 • 41 citations

Abnormal Cellular Copper Metabolism in the Blotchy Mouse

1978 • 36 citations

Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects β-amyloid peptide production

2004 • 35 citations

Copper metabolism in mottled mouse mutants. The effect of copper therapy on lysyl oxidase activity in brindled (Mobr) mice

1982 • 31 citations