Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors

1998 • 1,475 citations

Flow Cytometric Analysis of Respiratory Burst Activity in Phagocytes With Hydroethidine and 2′,7′-Dichlorofluorescin

1990 • 869 citations

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1996 • 868 citations

Superoxide Production and Expression of Nox Family Proteins in Human Atherosclerosis

2002 • 838 citations

Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells

1994 • 637 citations

Superoxide Production in Vascular Smooth Muscle Contributes to Oxidative Stress and Impaired Relaxation in Atherosclerosis

1998 • 631 citations

Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

1998 • 489 citations

Significant Levels of Oxidants are Generated by Isolated Cardiomyocytes During Ischemia Prior to Reperfusion

1997 • 391 citations

Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals

2001 • 367 citations

In Vivo Evidence for Microvascular Oxidative Stress in Spontaneously Hypertensive Rats

1995 • 341 citations

Production and Actions of Superoxide in the Renal Medulla

2001 • 295 citations

The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study

2002 • 273 citations

Ischemic preconditioning alters real-time measure of O₂ radicals in intact hearts with ischemia and reperfusion

2003 • 263 citations

Manganese Superoxide Dismutase Deficiency Exacerbates Cerebral Infarction After Focal Cerebral Ischemia/Reperfusion in Mice

2002 • 246 citations

Mitochondrial membrane potential and hydroethidine‐monitored superoxide generation in cultured cerebellar granule cells

1997 • 224 citations

Transferrin Receptor-dependent Iron Uptake Is Responsible for Doxorubicin-mediated Apoptosis in Endothelial Cells

2002 • 217 citations

Oxidative Stress, Mitochondrial Function, and Acute Glutamate Excitotoxicity in Cultured Cerebellar Granule Cells

1999 • 185 citations

Oxidative Stress–Induced Iron Signaling Is Responsible for Peroxide-Dependent Oxidation of Dichlorodihydrofluorescein in Endothelial Cells

2003 • 156 citations

Detection of superoxide anion using an isotopically labeled nitrone spin trap: potential biological applications

2000 • 148 citations

Exacerbation of Delayed Cell Injury After Transient Global Ischemia in Mutant Mice With CuZn Superoxide Dismutase Deficiency

1999 • 141 citations

In Vivo Evidence for Antioxidant Potential of Estrogen in Microvessels of Female Spontaneously Hypertensive Rats

2002 • 130 citations

Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical

2001 • 115 citations

The Role of Tetrahydrobiopterin in the Regulation of Neuronal Nitric-oxide Synthase-generated Superoxide

2002 • 93 citations

Increased NADPH Oxidase Activity, gp91phox Expression, and Endothelium-Dependent Vasorelaxation During Neointima Formation in Rabbits

2002 • 91 citations

Gene Transfer of Endothelial Nitric Oxide Synthase Reduces Angiotensin II–Induced Endothelial Dysfunction

2000 • 72 citations

Increased mitochondrial superoxide generation in neurons from trisomy 16 mice: a model of Down’s syndrome

2000 • 71 citations

Proton magnetic resonance studies of ethidium bromide and its sodium borohydride reduced derivative

1972 • 67 citations

Further studies on the formation of oxygen radicals by potassium superoxide in aqueous medium for biochemical investigations

1986 • 38 citations

Detection of reactive oxygen species by flow cytometry after spinal cord injury

2002 • 33 citations

In vitro quantitation of biological superoxide and hydrogen peroxide generation

2002 • 30 citations