Vitamin E Inhibits Abdominal Aortic Aneurysm Formation in Angiotensin II–Infused Apolipoprotein E–Deficient Mice

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.

1996 • 1,132 citations

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

2002 • 967 citations

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

2002 • 842 citations

Guidelines for the treatment of abdominal aortic aneurysms: Report of a subcommittee of the Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery

2003 • 804 citations

Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase and Components of Nitric Oxide/cGMP Signaling

2002 • 679 citations

Inflammation and Matrix Metalloproteinases in the Enlarging Abdominal Aortic Aneurysm

1995 • 671 citations

Role of NADH/NADPH Oxidase–Derived H ₂ O ₂ in Angiotensin II–Induced Vascular Hypertrophy

1998 • 616 citations

Rupture Rate of Large Abdominal Aortic Aneurysms in Patients Refusing or Unfit for Elective Repair

2002 • 570 citations

Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice

1998 • 509 citations

Ghrelin Inhibits Proinflammatory Responses and Nuclear Factor-κB Activation in Human Endothelial Cells

2004 • 485 citations

Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response.

1990 • 412 citations

Aortic Dissection Precedes Formation of Aneurysms and Atherosclerosis in Angiotensin II-Infused, Apolipoprotein E-Deficient Mice

2003 • 409 citations

Role of NADPH Oxidase in the Vascular Hypertrophic and Oxidative Stress Response to Angiotensin II in Mice

2001 • 336 citations

Non‐antioxidant molecular functions of α‐tocopherol (vitamin E)

2002 • 299 citations

Antagonism of AT2 receptors augments Angiotensin II‐induced abdominal aortic aneurysms and atherosclerosis

2001 • 285 citations

Angiotensin II–accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice

2003 • 272 citations

Oxidative Stress in Human Abdominal Aortic Aneurysms

2002 • 258 citations

Angiotensin II–accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice

2003 • 242 citations

The Role of Inflammation in Nonspecific Abdominal Aortic Aneurysm Disease

1991 • 236 citations

Cytokines that activate proteolysis are increased in abdominal aortic aneurysms.

1994 • 200 citations

Activation of Matrix Metalloproteinase-2 by Overexpression of Manganese Superoxide Dismutase in Human Breast Cancer MCF-7 Cells Involves Reactive Oxygen Species

2002 • 180 citations

Quantification of Atherosclerosis in Mice

2003 • 175 citations

Urokinase-Type Plasminogen Activator Plays a Critical Role in Angiotensin II–Induced Abdominal Aortic Aneurysm

2003 • 172 citations

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease

2002 • 161 citations

α-Tocopherol Enrichment of Monocytes Decreases Agonist-Induced Adhesion to Human Endothelial Cells

1998 • 127 citations

Angiotensin II Increases Urokinase-Type Plasminogen Activator Expression and Induces Aneurysm in the Abdominal Aorta of Apolipoprotein E-Deficient Mice

2001 • 121 citations

Report of a subcommittee of the Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery

2003 • 104 citations

Flow Loading Induces Macrophage Antioxidative Gene Expression in Experimental Aneurysms

2002 • 99 citations

The Effect of α-Tocopherol on Monocyte Proatherogenic Activity

2001 • 98 citations

Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II

2002 • 98 citations

17β-Estradiol Attenuates Development of Angiotensin II–Induced Aortic Abdominal Aneurysm in Apolipoprotein E–Deficient Mice

2003 • 96 citations

Oxysterol-induced activation of macrophage NADPH-oxidase enhances cell-mediated oxidation of LDL in the atherosclerotic apolipoprotein E deficient mouse: inhibitory role for vitamin E

2002 • 95 citations

Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: A study of the transcription profile with complementary DNA microarray

2002 • 89 citations

Regulation of angiotensin II‐stimulated osteopontin expression in cardiac microvascular endothelial cells: Role of p42/44 mitogen‐activated protein kinase and reactive oxygen species*

2001 • 78 citations

Vitamin E Reduces Progression of Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice With Established Vascular Lesions

2003 • 74 citations

Dietary β-Carotene and α-Tocopherol Combination Does Not Inhibit Atherogenesis in an ApoE–Deficient Mouse Model

1999 • 59 citations

Antioxidant Enzyme Activity in Human Abdominal Aortic Aneurysmal and Occlusive Disease

1999 • 49 citations

An Improved Assay Method for Serum Vitamins A and E Using Fluorometry

1978 • 30 citations

Antioxidant Enzyme Activity in Human Abdominal Aortic Aneurysmal and Occlusive Disease

1999 • 30 citations

Supplementation with Vitamin E and/or Zinc does not Attenuate Atherosclerosis in Apolipoprotein E-deficient Mice fed a High-Fat, High-Cholesterol Diet

2001 • 27 citations

Decrease of Plasma Vitamin E (α‐Tocopherol) Levels in Patients with Abdominal Aortic Aneurysm

1996 • 18 citations

Novel indices of oxidant stress in cardiovascular disease: specific analysis of F2-isoprostanes

1997 • 16 citations

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