Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris.

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Lymphocyte responses and cytokines

1994 • 1,860 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

A genome-wide search for human type 1 diabetes susceptibility genes

1994 • 1,294 citations

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

1991 • 1,014 citations

A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 • 707 citations

Induction of Pemphigus in Neonatal Mice by Passive Transfer of IgG from Patients with the Disease

1982 • 667 citations

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

1993 • 383 citations

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

1988 • 378 citations

Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic.

1992 • 337 citations

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones.

1994 • 323 citations

Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association.

1995 • 310 citations

Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes

1994 • 246 citations

A Newly Characterized HLA DQ _β Allele Associated with Pemphigus Vulgaris

1988 • 230 citations

Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris.

1990 • 226 citations

HLA class II allelic variation and susceptibility to pemphigus vulgaris.

1988 • 211 citations

Correlation of peptide specificity and IgG subclass with pathogenic and nonpathogenic autoantibodies in pemphigus vulgaris: a model for autoimmunity.

1995 • 200 citations

HLA Class II region nucleotide sequences, 1995

1995 • 145 citations

Sequence analysis of the HLA-DRß and HLA-DQß loci from three Pemphigus vulgaris patients

1988 • 113 citations

Pocket 4 of the HLA-DR(α,β 1*0401) molecule is a major determinant of T cells recognition of peptide.

1995 • 104 citations

Neonatal Pemphigus Vulgaris

1986 • 98 citations

Autoantibodies against adhesion molecules and structures in blistering skin diseases.

1995 • 80 citations

HLA‐DQA1, ‐DQB1 and ‐DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR‐RFLP method

1994 • 49 citations

Acidic residues in the DRβ chain third hypervariable region are required for stimulation of a DR(α,β1∗0402)-restricted T-cell clone

1994 • 14 citations

Genetics of RA: the HLA shared epitope hypothesis and its implications.

1991 • 6 citations

The Immunopathogenesis and Immunogenetics of Rheumatoid Arthritis

1989 • 3 citations