High Levels of Wilms' Tumor Gene (wt1) mRNA in Acute Myeloid Leukemias Are Associated With a Worse Long-Term Outcome

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Evaluation of survival data and two new rank order statistics arising in its consideration.

1966 • 7,595 citations

Proposals for the Classification of the Acute Leukaemias F<scp>rench</scp>‐A<scp>merican</scp>‐B<scp>ritish</scp> (FAB) C<scp>o‐operative</scp> G<scp>roup</scp>

1976 • 5,620 citations

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

WT-1 is required for early kidney development

1993 • 1,976 citations

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

The candidate Wilms' tumour gene is involved in genitourinary development

1990 • 884 citations

Absolute mRNA quantification using the polymerase chain reaction (PCR). A novel approach by aPCR aidedtranscipttitration assay (PATTY)

1989 • 659 citations

Alternative splicing and genomic structure of the Wilms tumor gene WT1.

1991 • 628 citations

WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia

1994 • 575 citations

Repression of the Insulin-Like Growth Factor II Gene by the Wilms Tumor Suppressor WT1

1992 • 535 citations

Expression of the Wilms' tumor gene (WT1) in human leukemias.

1992 • 354 citations

Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.

1988 • 301 citations

Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis

1996 • 268 citations

Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias.

1995 • 263 citations

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.

1992 • 226 citations

Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1.

1995 • 206 citations

The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains

1993 • 198 citations

Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product.

1994 • 193 citations

Long-term follow-up of minimal residual disease in leukemia patients by monitoring WT1 (Wilms tumor gene) expression levels

1996 • 187 citations

Mutations in the Wilms' tumor gene WT1 in leukemias

1996 • 176 citations

Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus.

1993 • 171 citations

The WT1 Wilms' tumor suppressor gene: How much do we really know?

1996 • 168 citations

Expression of the candidate Wilm's tumor gene, WT1, in human leukemia cells.

1993 • 152 citations

The Wilms' tumor suppressor gene WT1 is negatively autoregulated.

1994 • 133 citations

The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells.

1994 • 115 citations

Expression of the Wilms' tumor suppressor gene WT1 during mouse embryogenesis.

1993 • 113 citations

Downregulation of Wilms' tumor gene (wt1) during myelomonocytic differentiation in HL60 cells

1994 • 109 citations

Wilms' tumor gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells.

1994 • 87 citations

Expression of the WT1 Wilms' tumor gene by normal and malignant human melanocytes

1994 • 74 citations

Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product

1994 • 70 citations

Inactivation of the remaining allele of the WT1 gene in a Wilms' tumour from a WAGR patient.

1992 • 60 citations

Interleukin-2 Bolus Infusion as Late Consolidation Therapy in 2nd Remission of Acute Myeloblastic Leukemia

1995 • 52 citations

WT1: a novel tumor suppressor gene inactivated in Wilms' tumor.

1992 • 48 citations

The Wilms' tumor gene is frequently expressed in acute myeloblastic leukemias and may provide a marker for residual blast cells detectable by PCR

1995 • 47 citations

Molecular mechanisms possibly affecting WT1 function in human ovarian tumors

1994 • 43 citations

RNA polymerase chain reaction detects different levels of four alternatively spliced WT1 transcripts in Wilms' tumors.

1992 • 39 citations

Bone marrow-derived T-cell clones obtained from untreated acute myelocytic leukemia exhibit blast directed autologous cytotoxicity

1995 • 26 citations

Cytogenetics and oncogenes in leukemia

1994 • 7 citations