Upregulation and activation of PKCα by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKCα and Src inhibitors

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Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

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Src family kinases in tumor progression and metastasis.

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The hunting of the Src

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The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy.

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Overexpression of ErbB2 Blocks Taxol-Induced Apoptosis by Upregulation of p21Cip1, which Inhibits p34Cdc2 Kinase

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PKC at a glance

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Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

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Activation of the Akt/Mammalian Target of Rapamycin/4E-BP1 Pathway by ErbB2 Overexpression Predicts Tumor Progression in Breast Cancers

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MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype.

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Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Cα

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Signaling Pathways Responsible for Cancer Cell Invasion as Targets for Cancer Therapy

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High PKC α and Low E-Cadherin Expression Contribute to High Migratory Activity of Colon Carcinoma Cells

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Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma.

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Roles of plakoglobin end domains in desmosome assembly

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Combined trastuzumab and paclitaxel treatment better inhibits ErbB‐2‐mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone

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ErbB2 Promotes Src Synthesis and Stability: Novel Mechanisms of Src Activation That Confer Breast Cancer Metastasis

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Interaction of estrogen receptor α with protein kinase C α and c-Src in osteoblasts during differentiation

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The future of cytotoxic therapy: selective cytotoxicity based on biology is the key

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Combination of an Src Kinase Inhibitor with a Novel Pharmacological Antagonist of the Urokinase Receptor Diminishes in Vitro Colon Cancer Invasiveness

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Inhibition of Protein Kinase Cα Enhances Anticancer Agent-Induced Loss of Anchorage-Independent Growth Regardless of Protection against Apoptosis by Bcl-2

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