Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

2000 • 3,559 citations

Mitochondrial Complex I Deficiency in Parkinson's Disease

1990 • 2,147 citations

MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE

1989 • 1,717 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

2000 • 1,526 citations

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

1994 • 1,214 citations

Peroxynitrite formation from macrophage-derived nitric oxide

1992 • 1,118 citations

[23] Oxidative chemistry of peroxynitrite

1994 • 981 citations

Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

1977 • 854 citations

Persistent inhibition of cell respiration by nitric oxide: Crucial role ofS-nitrosylation of mitochondrial complex I and protective action of glutathione

1998 • 825 citations

Nitric Oxide Inhibits Electron Transfer and Increases Superoxide Radical Production in Rat Heart Mitochondria and Submitochondrial Particles

1996 • 726 citations

Differential Inhibitory Action of Nitric Oxide and Peroxynitrite on Mitochondrial Electron Transport

1996 • 719 citations

Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pressure Stopped-Flow Technique, and Pulse Radiolysis

1997 • 620 citations

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase

1995 • 540 citations

Irreversible Inhibition of Mitochondrial Complex I by 1‐Methyl‐4‐Phenylpyridinium: Evidence for Free Radical Involvement

1992 • 371 citations

Inhibition of Electron and Energy Transfer in Mitochondria

1963 • 363 citations

A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: Its use in the simultaneous fluorimetric assay of cellular activation processes

1984 • 322 citations

Swelling and contraction of the mitochondrial matrix. I. A structural interpretation of the relationship between light scattering and matrix volume.

1985 • 237 citations

Reversal of nitric oxide-, peroxynitrite- and S-nitrosothiol-induced inhibition of mitochondrial respiration or complex I activity by light and thiols

2000 • 194 citations

Endogenous peroxynitrite mediates mitochondrial dysfunction in rat diaphragm during endotoxemia

1999 • 186 citations

The Regulation of Mitochondrial Oxygen Uptake by Redox Reactions Involving Nitric Oxide and Ubiquinol

1999 • 183 citations

The reaction of nitric oxide with ubiquinol: kinetic properties and biological significance

1999 • 155 citations

[20] Regulation of mitochondrial respiration by adenosine diphosphate, oxygen, and nitric oxide

1999 • 139 citations

Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage

2000 • 76 citations

Determination of the structures of respiratory enzyme complexes from mammalian mitochondria

1995 • 42 citations

Continuous exposure to high concentrations of nitric oxide leads to persistent inhibition of oxygen consumption by J774 cells as well as extraction of oxygen by the extracellular medium

2000 • 38 citations

Inhibition of electron and energy transfer in mitochondria by 19-nor-ethynyltestosterone acetate

1970 • 29 citations

Continuous exposure to high concentrations of nitric oxide leads to persistent inhibition of oxygen consumption by J774 cells as well as extraction of oxygen by the extracellular medium

2000 • 14 citations

The action of bothrops neuwiedii phospholipase A2 on mitochondrial phospholipids and electron transfer

1973 • 9 citations

Aberrant Oxygen Metabolism in Neoplastic Cells Injured by Cytotoxic Macrophages

1985 • 1 citations